The effect of microwave irradiation on carbodiimide-mediated esterifications on solid support 机翻标题: 暂无翻译,请尝试点击翻译按钮。

来源
Tetrahedron
年/卷/期
2001 / V.57 / N.18
页码
3915-3920
作者单位
Institute of Chemistry,Karl-Franzens-University Graz,Heinrichstrasse 28,A-8010 Graz,Austria;
作者
Alexander Stadler;
摘要
The esterification of a polymer-supported alcohol (PS Wang resin) with benzoic acid was investigated using microwave irradiation.Activation of the carboxylic acid was carried out using diisopropylcarbodiimide,either via the O-acylisourea or symmetrical anhydride protocols.In the microwave-assisted solid-phase coupling using the O-acylisourea method the main product of the reaction was 1-benzoyl-1,3-diisopropylrea,formed by rearrangement of the thermolabile isourea intermediate.On the other hand,significant rate enhancements were observed for the coupling of benzoic anhydride to Wang resin using microwave flash heating in 1-methyl-2-pyrrolidone as solvent.Reaction times were reduced from 2 to 3 days using conventional conditions,to 10min by microwave dielectric beating.
机翻摘要
暂无翻译结果,您可以尝试点击头部的翻译按钮。
正文
Alexander Stadler; Institute of Chemistry,Karl-Franzens-University Graz,Heinrichstrasse 28,A-8010 Graz,Austria; Tetrahedron; V.57 N.18 2001; 3915-3920
若您需要申请原文,请登录。

最新评论

暂无评论。

登录后可以发表评论

意见反馈
返回顶部