(US8598119) The invention claimed is: 1. A method for the treatment of one or more 5-HT2A-related disorders, comprising administering to a patient in need thereof a Compound of Formula I: wherein X is O, -- NH or -- N(CH3); and Y is -- O -- or -- C(O) -- , in free or pharmaceutically acceptable salt form, in a dose which selectively blocks the 5-HT2A receptor. 2. The method according to claim 1 wherein said one or more disorders is psychosis. 3. The method according to claim 1 wherein said one or more disorders is schizophrenia. 4. The method according to claim 1 wherein said one or more disorders is depression. 5. The method according to claim 1 wherein said patient is unable to tolerate the side effects of conventional antipsychotic drugs. 6. The method according to claim 5 wherein said antipsychotic drugs are selected from the group consisting of haloperidol, aripiparazole, clozapine, olanzapine, quetiapine, risperidone and zipasidone. 7. The method according to claim 1 wherein said one or more disorders is depression and said patient is a patient suffering from psychosis or Parkinson's disease. 8. The method according to claim 1 wherein said one or more disorders is sleep disorder and said patient is suffering from depression. 9. The method according to claim 1 wherein said one or more disorders is sleep disorder and said patient is suffering from psychosis. 10. The method according to claim 1 wherein said one or more disorders is sleep disorder and said patient is suffering from Parkinson's disease. 11. The method according to claim 1 wherein said one or more disorders is sleep disorder and said patient is suffering from depression and psychosis or Parkinson's disease. 12. The method according to claim 1 wherein at least one of the disorders is dyskinesia. 13. The method of claim 12 wherein the disorder is levodopa-induced dyskinesia in a patient suffering from Parkinson's disease. 14. The method according to claim 1, further comprising one or more therapeutic agents selected from the group consisting of compounds that modulate GABA activity, a GABAB agonist, a 5-HT modulator, a melatonin agonist, an ion channel modulator, a serotonin-2 antagonist/reuptake inhibitor (SARIs), an orexin receptor antagonist, an H3 agonist, a noradrenergic antagonist, a galanin agonist, a CRH antagonist, human growth hormone, a growth hormone agonist, estrogen, an estrogen agonist, a neurokinin-1 drug, an anti-depressant, and an antipsychotic agent, in free or pharmaceutically acceptable salt form. 15. The method according to claim 1, further comprising administering one or more therapeutic agents selected from the group consisting of modafinil, armodafinil, doxepin, alprazolam, bromazepam, clobazam, clonazepam, clorazepate, diazepam, flunitrazepam, flurazepam, lorazepam, midazolam, nitrazepam, oxazepam, temazapam, triazolam, indiplon, zopiclone, eszopiclone, zaleplon, Zolpidem, gabaxadol, vigabatrin, tiagabine, EVT 201, estazolam, ketanserin, risperidone, eplivanserin, volinanserin pruvanserin, MDL 100907, HY10275, APD125, AVE8488, repinotan, sarizotan, eptapirone, buspirone, MN-305, melatonin, ramelteon, VEC-162, PD-6735, agomelatine, lamotrigine, gabapentin, pregabalin, orexin, a 1,3-biarylurea, SB-334867-a, GW649868, a benzamide derivative, Org 50081, ritanserin, nefazodone, serzone, trazodone, Casopitant, amitriptyline, amoxapine, bupropion, citalopram, clomipramine, desipramine, doxepin, duloxetine, escitaloprame, fluoxetine, fluvoxamine, imipramine, isocarboxazid, maprotiline, mirtazapine, nefazodone, nortriptyline, paroxetine, phenlzine sulfate, protiptyline, sertraline, tranylcypromine, trazodone, trimipramine, velafaxine, chlorpromazine, haloperidol, droperidol, fluphenazine, loxapine, mesoridazine molidone, perphenazine, pimozide, prochlorperazine promazine, thioridazine, thiothixene, trifluoperazine, clozapine, aripiparazole, olanzapine, quetiapine, risperidone, ziprasidone and paliperidone, in free or pharmaceutically acceptable salt form. 16. A method for the treatment of one or more sleep disorders comprising administering to a patient in need thereof a Compound of Formula I: wherein X is O, -- NH or -- N(CH3); and Y is -- O -- or -- C(O) -- , in free or pharmaceutically acceptable salt form, in an amount that selectively blocks the 5-HT2A receptor, such that it a) is sufficient to block said 5-HT2A receptor; and b) either does not block, or minimally blocks the dopamine D2 receptor. 17. The method according to claim 16, wherein the sleep disorder is sleep maintenance insomnia. 18. The method according to claim 16, further comprising one or more therapeutic agents selected from the group consisting of compounds that modulate GABA activity, a GABAB agonist, a 5-HT modulator, a melatonin agonist, an ion channel modulator, a serotonin-2 antagonist/reuptake inhibitor (SARIs), an orexin receptor antagonist, an H3 agonist, a noradrenergic antagonist, a galanin agonist, a CRH antagonist, human growth hormone, a growth hormone agonist, estrogen, an estrogen agonist, a neurokinin-I drug, an anti-depressant, and an antipsychotic agent, in free or pharmaceutically acceptable salt form. 19. The method according claim 16, further comprising administering one or more therapeutic agents selected from the group consisting of modafinil, armodafinil, doxepin, alprazolam, bromazepam, clobazam, clonazepam, clorazepate, diazepam, flunitrazepam, flurazepam, lorazepam, midazolam, nitrazepam, oxazepam, temazapam, triazolam, indiplon, zopiclone, eszopiclone, zaleplon, Zolpidem, gabaxadol, vigabatrin, tiagabine, EVT 201, estazolam, ketanserin, risperidone, eplivanserin, volinanserin, pruvanserin, MDL 100907, HY10275, APD125, AVE8488, repinotan, sarizotan, eptapirone, buspirone, MN-305, melatonin, ramelteon, VEC-162, PD-6735, agomelatine, lamotrigine, gabapentin, pregabalin, orexin, a 1,3-biarylurea, SB-334867-a, GW649868, a benzamide derivative, Org 50081, ritanserin, nefazodone, serzone, trazodone, Casopitant, amitriptyline, amoxapine, bupropion, citalopram, clomipramine, desipramine, doxepin, duloxetine, escitaloprame, fluoxetine, fluvoxamine, imipramine, isocarboxazid, maprotiline, mirtazapine, nefazodone, nortriptyline, paroxetine, phenlzine sulfate, protiptyline, sertraline, tranylcypromine, trazodone, trimipramine, velafaxine, chlorpromazine, haloperidol, droperidol, fluphenazine, loxapine, mesoridazine molidone, perphenazine, pimozide, prochlorperazine promazine, thioridazine, thiothixene, trifluoperazine, clozapine, aripiparazole, olanzapine, quetiapine, risperidone, ziprasidone and paliperidone, in free or pharmaceutically acceptable salt form. 20. The method according to claim 16, wherein the effective amount of the Compound of Formula I administered is 0.5-10 mg. 21. The method according to claim 16, wherein the amount of the Compound of Formula I administered is 2.5-5 mg. 22. The method according to claim 16, wherein the amount of the Compound of Formula I administered is less than 5 mg. 23. The method according to claim 16, wherein the amount of the Compound of Formula I administered is less than 2.5 mg. 24. The method of claim 16 wherein the sleep disorder is insomnia in a patient suffering from depression. 25. The method according to claim 1, further comprising administering one or more therapeutic agents selected from a group consisting of as L-dopa, co-careldopa, duodopa, stalova, symmetrel, benzotropine, biperiden, bromocryiptine, entacapone, pergolide, pramipexole, procyclidine, ropinirole, selegiline and tolcapone. 26. The method according to claim 16, further comprising administering one or more therapeutic agents selected from a group consisting of as L-dopa, co-careldopa, duodopa, stalova, symmetrel, benzotropine, biperiden, bromocryiptine, entacapone, pergolide, pramipexole, procyclidine, ropinirole, selegiline and tolcapone. 27. The method according to claim 1, wherein the compound of Formula I has the structure: 28. The method according to claim 1, wherein the dose of said Compound of Formula I is from 2.5 mg to 50 mg. 29. The method according to claim 16, wherein the compound of Formula I has the structure:
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