Acetylcholinesterase-based biosensing solutions for the detection of organophosphorus pesticides 机翻标题: 暂无翻译,请尝试点击翻译按钮。

会议集名/来源
Proceedings of the SPIE
出版年
2019
页码
111762V (9 pp.)
出版物地点
USA
会议日期
2019-05-26 - 2019-06-02
作者
Walter, Piotr 1;Pepłowski, Andrzej 1;Janczak, Daniel 1;Jakubowska, Małgorzata 1 1 Fac. of Mechatron., Warsaw Univ. of Technol., Warsaw, Warsaw University of Technology, Faculty of Mechatronics, Św. Andrzeja Boboli 8, Warsaw, 02-525, Poland
摘要
Numerous biosensing configurations have been researched for detection of organophosphorus pesticides in agricultural and household applications. Selectivity for the specific insecticide, sensitivity and low detection limit being the main challenges gives a great potential to targeted enzymatic biosensors. Acetylcholinesterase is being employed in receptors, because organophosphorus pesticides, such as malathion, display inhibitory effect towards it. Proteins within other structures can have decreased activity, be contaminated, denatured or have a diffusion barrier resulting in reduced interaction with the analyte. Choice of the immobilization method for the enzyme may be the most important aspect in the development of electrochemical biosensor. Numerous acetylcholinesterase based biosensing solutions for the detection of organophosphorus pesticides have been reviewed.
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关键词
biosensors;chemical sensors;enzymes;proteins
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