Administration of a selective il-6-trans-signalling inhibitor 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
CA2969301 A1 2016-06-09 [CA2969301] / 2016-06-09
申请号/申请日
2015CA-2969301 / 2015-12-01
发明人
COTTINGHAM IAN;PETRI NICLAS AXEL;
申请人
FERRING;
主分类号
IPC分类号
A61K-038/16A61K-038/20A61P-001/00C07K-014/715
摘要
(CA2969301) A selective IL-6-trans-signalling inhibitor can be used to treat a variety of IL-6- mediated conditions, including inflammatory diseases and cancer.  The inhibitor can safely be administered to humans at a variety of doses.  Moreover, the inhibitor lessens deleterious effects associated with other IL-6 inhibitors such as lowering neutrophil counts, platelet counts and levels of C-reactive protein.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2014US-62086054 2014-12-01 2015WO-IB02459 2015-12-01
主权利要求
(CA2969301) 1. A polypeptide dimer comprising two monomers, each monomer having at least 90% sequence identity to SEQ ID NO: 1, wherein the monomers comprise the gp130 D6 domain corresponding to the amino acids at positions 585-595 of SEQ ID NO:1, an Fc d
法律状态
(CA2969301) LEGAL DETAILS FOR CA2969301  Actual or expected expiration date=2035-12-01    Legal state=ALIVE    Status=PENDING     Event publication date=2015-12-01  Event code=CA/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=CA CA2969301  Application date=2015-12-01  Standardized application number=2015CA-2969301     Event publication date=2016-06-09  Event code=CA/A1  Event type=Examination events  Application laid open  Publication country=CA  Publication number=CA2969301  Publication stage Code=A1  Publication date=2016-06-09  Standardized publication number=CA2969301
专利类型码
A1
国别省市代码
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