Use of active substances for controlling virus infection in plants 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
WO2017121809 A1 2017-07-20 [WO2017121809] / 2017-07-20
申请号/申请日
2017WO-EP50583 / 2017-01-12
发明人
BALTZ RACHEL;BERNIER DAVID;JAY-BRIOUDES FLORENCE;KNOBLOCH THOMAS;VITEL MAXIME;VOINNET OLIVIER;
申请人
BAYER CROPSCIENCE;
主分类号
IPC分类号
A01N-043/08A01N-043/36A01N-043/40A01N-043/60A01N-043/84A01N-043/90A01P-015/00
摘要
(WO2017121809) The use of specific active substances, alone or in combination, for controlling virus infections in plants and a method for using said specific active substances for controlling said virus infections in the field of plant protection and the protection of materials are disclosed.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2016EP-0290008 2016-01-13
主权利要求
(WO2017121809) 1. Claims: A method for controlling viral diseases in plants, which comprises applying to the plants at least one compound of formula (I) :  - Rl is a phenyl that may be substituted with one or more halogens ; - R2 is a -NR'R" group wherein : - R' and R" are independently selected from the group consisting of (Ci-Ce)alkyl and (C3-C6)cycloalkyl, or - R' and R" together with the nitrogen atom to which they are attached form a 5- or 6-membered heterocycle chosen from pyrrolidine, piperidine, morpholine, or piperazine, wherein said heterocycle may be substituted with one or more substituents selected from the group consisting of halogen, (Ci- Ce)alkyl and (Ci-Ce)cyanoalkyl, or - R' and R" together with the nitrogen atom to which they are attached form an azabicycloalkyl that may be substituted with a (Ci-C6)haloalkyl. 2. The method according to claim 1, wherein Rl is selected from the group consisting of 3-chlorophenyl, 4-chlorophenyl, 4-bromophenyl, 2,3-dichlorophenyl and 3,4- dichlorophenyl. The method according to claim 1 or 2 wherein R2 is selected from the group consisting of -NEt2, -N(n-Pr)2, -N(c-pentyl)Me, piperidin-l-yl, pyrrolidin-l-yl, N-morpholino, 4,4-difluoropiperidin- 1 -yl, 4-(2-cyanoethyl)-piperazin- 1 -yl, 2,6-dimethylmorpholin-4-yl and 6-(trifluoromethyl)-3-azabicyclo[3.1.0]hex-3-yl. The method according to anyone of claims 1 to 3, wherein the control is based on a stimulation of the natural defense mechanism of plants against viruses. The method according to claim 4, wherein the natural defense mechanism of plants against viruses is a RNA-silencing based plant defense mechanism. The method according to anyone of the preceding claims, wherein said method is a preventive method. The method according to anyone of the preceding claims, wherein said plants are selected from the group consisting of cotton, flax, grapevine, fruit, vegetables, crop plants, ornamental plants for gardens and wooded area and genetically modified varieties of each of these plants. The method according to anyone of the preceding claims, wherein said plants are selected from the group consisting of Ribesioidae sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp., Actinidaceae sp., Lauraceae sp., Musaceae sp., Rubiaceae sp., Theaceae sp., Sterculiceae sp., Rutaceae sp. ; Solanaceae sp., Liliaceae sp., Asteraceae sp., Umbelliferae sp., Cruciferae sp., Chenopodiaceae sp., Cucurbitaceae sp., Alliaceae sp., Papilionaceae sp., Asteraceae sp., Brassicaceae sp., Fabacae sp. , Papilionaceae sp. , Solanaceae sp. and Chenopodiaceae sp.. The method according to anyone of the preceding claims, wherein said viruses are selected from the group consisting of the following families or genus: Caulimoviridae, Geminiviridae, Bromoviridae, Closteroviridae, Comoviridae Potyviridae, Sequiviridae, Tombusviridae, Rhabdoviridae, Bunyaviridae, Partitiviridae, Rheoviridae, Capillovirus, Carlavirus, Enamovirus, Furovirus, Hordeivirus, Idaeovirus, Luteovirus, Marafivirus, Potexvirus, Sobemovirus, Tenuivirus, Tobamovirus, Tobravirus, Trichovirus, Tymovirus and Umbravirus. The method according to anyone of the preceding claims, wherein said viruses are selected from the group consisting of Turnip mosaic virus, turnip crinkle virus, bean pod mottle virus, cauliflower mosaic virus, tobacco mosaic virus, tomato bushy stunt virus, rice ragged stunt virus, cucumber mosaic virus, barley yellow dwarf virus, beet yellows virus, lettuce yellows virus, maise mosaic virus, peanut stunt virus and potato virus Y. 11. The method according to anyone of the preceding claims, wherein the compound of formula (I) is applied by spraying to the plants. 12. The method according to anyone of the preceding claims, wherein the compound of formula (I) is applied to the plants in an amount ranging from 0.01 to 5kg ha. 13. Use of a compound of formula (I) as defined in claim 1, 2 or 3 for stimulating the natural defense mechanism of plants against viruses. 14. Use according to claim 13 for stimulating the RNA-silencing-based plant defense mechanism. 15. Use of a compound of formula (I) as defined in claim 1, 2 or 3 to improve agronomic traits and/or to provide resistance against pathogens, insect, pest and/or to provide stress tolerance in genetically modified plants transformed with an RNAi construct. 16. A compound of formula (I) :  wherein - Rl is a phenyl substituted with one or more halogens ; - R2 is a -NR'R" group wherein : - R' and R" are independently selected from the group consisting of (Ci-C6)alkyl and (C3-C6)cycloalkyl, or - R' and R" together with the nitrogen atom to which they are attached form a substituted piperidine or morpholine, wherein said substituted piperidine or morpholine is substituted with one or more substituents selected from the group consisting of halogen and (Ci-C6)alkyl, or - R' and R" together with the nitrogen atom to which they are attached form an azabicycloalkyl that may be substituted with a (Ci-C6)haloalkyl. 17. A compound of formula (I)  (I) wherein - Rl is a phenyl that may be substituted with one or more halogens ; - R2 is a -NR'R" group wherein : - R' and R" are independently selected from the group consisting of (Ci-Ce)alkyl and (C3-C6)cycloalkyl, or - R' and R" together with the nitrogen atom to which they are attached form a 5- or 6-membered heterocycle chosen from pyrrolidine, piperidine, morpholine, or piperazine, wherein said heterocycle may be substituted with one or more substituents selected from the group consisting of halogen, (Ci- Ce)alkyl and (Ci-Ce)cyanoalkyl, or - R' and R" together with the nitrogen atom to which they are attached form an azabicycloalkyl that may be substituted with a (Ci-C6)haloalkyl ; s a medicament.
法律状态
(WO2017121809) LEGAL DETAILS FOR WO2017121809  Actual or expected expiration date=2019-07-13    Legal state=ALIVE    Status=PENDING     Event publication date=2017-01-12  Event code=WO/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=WO WOEP2017050583  Application date=2017-01-12  Standardized application number=2017WO-EP50583     Event publication date=2017-07-20  Event code=WO/A1  Event type=Examination events  Published application with search report  Publication country=WO  Publication number=WO2017121809  Publication stage Code=A1  Publication date=2017-07-20  Standardized publication number=WO2017121809  LEGAL DETAILS FOR DESIGNATED STATE EP  Actual or expected expiration date=2037-01-12    Legal state=ALIVE    Status=PENDING   Corresponding cc:  Designated or member state=EP Corresponding appl: EP17701804    Event publication date=2017-09-13  Event code=WO/121  Event type=Designated states  EP: The EPO has been informed by wipo that ep was designated in this application Corresponding cc:  Designated or member state=EP
专利类型码
A1
国别省市代码
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