Method of inhibiting dopaminergic cell death 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2014323408 A1 2014-10-30 [US20140323408] / 2014-10-30
申请号/申请日
2014US-14271755 / 2014-05-07
发明人
SCHRATTENHOLZ ANDRÉ;
申请人
MIND NRG;MING NRG;
主分类号
IPC分类号
C07K-014/475
摘要
(US20140323408) Soluble Neuregulin-1 isoforms representing Posttranslational Neuregulin-1 modifications for reducing dopaminergic cell death.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2007US-60988576 2007-11-16 2008WO-EP09715 2008-11-17 2010US-12742983 2010-05-14 2014US-14271755 2014-05-07
主权利要求
(US20140323408) 1. A method of reducing dopaminergic cell death in a subject in need thereof, comprising administering to said subject an effective amount of recombinant soluble Type I Neuregulin-1 beta isoform which is an about 15 to about 35 kD N-terminal fragment of Type I Neuregulin-1 beta . 6. A method of promoting neuroprotection comprising administering a recombinant soluble Type I Neuregulin-1 beta isoform which is an about 15 to about 35 kD N-terminal fragment of Type I Neuregulin-1 beta to a subject in need thereof. 11. A method of enhancing memory in a subject in need thereof comprising administering to said subject a recombinant soluble Type I Neuregulin-1 beta isoform which is an about 15 to about 35 kD N-terminal fragment of Type I Neuregulin-1 beta . 16. A method of effecting antipsychotic activity in a subject in need thereof comprising administering to said subject a recombinant soluble Type I Neuregulin-1 beta isoform which is an about 15 to about 35 kD N-terminal fragment of Type I Neuregulin-1 beta .
法律状态
(US20140323408) LEGAL DETAILS FOR US2014323408  Actual or expected expiration date=2016-08-09    Legal state=DEAD    Status=LAPSED     Event publication date=2014-05-07  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US14271755  Application date=2014-05-07  Standardized application number=2014US-14271755     Event publication date=2014-05-07  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: ULM, JOHN D    Event publication date=2014-05-07  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1649     Event publication date=2014-05-07  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: MNRV-007C01US 323191-2087 Customer Nbr: 58249    Event publication date=2014-05-07  Event code=US/ENT  Event type=Administrative notifications  Business Entity Status: UNDISCOUNTED    Event publication date=2014-05-07  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=2014-05-07  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2014-05-07  Event code=US/ENTYSTA  Event type=Administrative notifications  Entity Status Set to Undiscounted    Event publication date=2014-05-22  Event code=US/APPFILEREC  Event type=Administrative notifications  Event type=OAO  Filing Receipt    Event publication date=2014-07-22  Event code=US/PTARDY  Event indicator=Pos  Event type=Examination events  Patent Term Adjustment - Ready for Examination    Event publication date=2014-07-25  Event code=US/RECEIPTUP  Event type=Administrative notifications  Event type=OAO  Filing Receipt - Updated    Event publication date=2014-08-05  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner in GAU    Event publication date=2014-10-30  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2014323408  Publication stage Code=A1  Publication date=2014-10-30  Standardized publication number=US20140323408     Event publication date=2014-10-30  Event code=US/PGPUBN  Event indicator=Pos  Event type=Examination events  Event type=OAO  PG-Pub Issue Notification    Event publication date=2015-04-14  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2015-06-26  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2015-07-10  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2015-10-16  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2016-01-06  Event code=US/CTFR  Event type=Examination events  Event type=OA  Event type=OAO  Final Rejection    Event publication date=2016-04-11  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: PROTEOSYS AG, GERMANY  Effective date of the event=2010-05-11  ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNOR:SCHRATTENHOLZ, ANDRE REEL/FRAME:038241/0359     Event publication date=2016-04-25  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: MING-NRG SA, SWITZERLAND  Effective date of the event=2014-02-11  ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNOR:PROTEOSYS AG REEL/FRAME:038506/0881     Event publication date=2016-05-11  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: MIND-NRG SA, SWITZERLAND  Effective date of the event=2014-02-11  CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 038506 FRAME: 0881.ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT ASSIGNOR:PROTEOSYS AG REEL/FRAME:038684/0686     Event publication date=2016-05-11  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment  Effective date of the event=2014-02-11  CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 038506 FRAME: 0881.ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT ASSIGNOR:PROTEOSYS AG REEL/FRAME:038684/0686     Event publication date=2016-07-08  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: MIND-NRG SARL, SWITZERLAND  Effective date of the event=2016-01-27  CHANGE OF NAME ASSIGNOR:MIND-NRG SA REEL/FRAME:039289/0137     Event publication date=2016-08-09  Event code=US/ABNOA  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=OAO  Abandoned -- Failure to Respond to an Office Action    Event publication date=2016-10-11  Event code=US/RECEIPTCOR  Event type=Administrative notifications  Event type=OAO  Filing Receipt - Corrected
专利类型码
A1
国别省市代码
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