Pharmaceutical composition comprising bicyclic nitrogen-containing aromatic heterocyclic amide compound as active ingredient 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
CA2972230 A1 2016-06-16 [CA2972230] / 2016-06-16
申请号/申请日
2015CA-2972230 / 2015-12-08
发明人
NAGASHIMA TAKEYUKI;
申请人
ASTELLAS PHARMA;
主分类号
IPC分类号
A61K-031/496A61K-031/497A61P-035/00A61P-043/00C07D-401/14
摘要
(CA2972230) [Problem] To provide a pharmaceutical composition for treating various cancers in which mitochondrial complex I is involved, in particular, colon cancer, leukemia and/or malignant lymphoma. [Solution] With the intention of creating pharmaceutical compositions for treating various cancers, the inventors confirmed, on the basis of the result of intensive investigation, that pharmaceutical compositions, which contain specific bicyclic nitrogen-containing aromatic heterocyclic amide compounds having an AMPK activation effect and mitochondrial complex I inhibition effect as active ingredients, have a therapeutic effect on various cancers in which mitochondrial complex I is involved, in particular, colon cancer, leukemia and/or malignant lymphoma, thereby completing the present invention.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2014JP-0249346 2014-12-09 2014JP-0249347 2014-12-09 2014JP-0249349 2014-12-09 2015WO-JP84456 2015-12-08
主权利要求
(CA2972230) Claims [Claim 1] A pharmaceutical composition for treating cancer selected from colorectal cancer, leukemia, and malignant lymphoma, the composition comprising: a compound selected from (5-{1-[(6-methoxypyridin-3-yl)methyl]piperidin-4-yl}- 1H-
法律状态
(CA2972230) LEGAL DETAILS FOR CA2972230  Actual or expected expiration date=2035-12-08    Legal state=ALIVE    Status=PENDING     Event publication date=2015-12-08  Event code=CA/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=CA CA2972230  Application date=2015-12-08  Standardized application number=2015CA-2972230     Event publication date=2016-06-16  Event code=CA/A1  Event type=Examination events  Application laid open  Publication country=CA  Publication number=CA2972230  Publication stage Code=A1  Publication date=2016-06-16  Standardized publication number=CA2972230
专利类型码
A1
国别省市代码
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