(CA2972230) [Problem] To provide a pharmaceutical composition for treating various cancers in which mitochondrial complex I is involved, in particular, colon cancer, leukemia and/or malignant lymphoma. [Solution] With the intention of creating pharmaceutical compositions for treating various cancers, the inventors confirmed, on the basis of the result of intensive investigation, that pharmaceutical compositions, which contain specific bicyclic nitrogen-containing aromatic heterocyclic amide compounds having an AMPK activation effect and mitochondrial complex I inhibition effect as active ingredients, have a therapeutic effect on various cancers in which mitochondrial complex I is involved, in particular, colon cancer, leukemia and/or malignant lymphoma, thereby completing the present invention.
(CA2972230) Claims [Claim 1] A pharmaceutical composition for treating cancer selected from colorectal cancer, leukemia, and malignant lymphoma, the composition comprising: a compound selected from (5-{1-[(6-methoxypyridin-3-yl)methyl]piperidin-4-yl}- 1H-
(CA2972230) LEGAL DETAILS FOR CA2972230 Actual or expected expiration date=2035-12-08 Legal state=ALIVE Status=PENDING Event publication date=2015-12-08 Event code=CA/APP Event indicator=Pos Event type=Examination events Application details Application country=CA CA2972230 Application date=2015-12-08 Standardized application number=2015CA-2972230 Event publication date=2016-06-16 Event code=CA/A1 Event type=Examination events Application laid open Publication country=CA Publication number=CA2972230 Publication stage Code=A1 Publication date=2016-06-16 Standardized publication number=CA2972230
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