Cardiac muscle function and manipulation 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2017189489 A1 2017-07-06 [US20170189489] / 2017-07-06
申请号/申请日
2016US-15236302 / 2016-08-12
发明人
ZHOU MINGDONG;
申请人
ZENSUN (SHANGHAI) SCI & TECH;
主分类号
IPC分类号
A61K-038/18A61K-038/19A61K-048/00A61P-009/00C12N-005/077G01N-033/68G01N-033/74
摘要
(US20170189489) A method of causing cardiomyocyte growth and/or differentiation, the method comprising exposing a cardiomyocyte to neuregulin (NRG) thereby activating the MAP kinase pathway in the cardiomyocyte and causing growth and/or differentiation of the cardiomyocyte.  Use of neuregulin, neuregulin polypeptide, neuregulin derivatives, or compounds which mimic the activities of neuregulins in the treatment or management of heart disease and heart failure in a mammal.
机翻摘要
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地址
代理人
代理机构
;
优先权号
1998AU-0007850 1998-12-21 1999WO-AU01137 1999-12-21 2002US-09980672 2002-03-08 2006US-11429204 2006-05-04 2016US-15236302 2016-08-12
主权利要求
(US20170189489) 1. A method for treating heart failure in a mammal in need thereof, comprising administering an effective amount of a neuregulin or a neuregulin analog to the mammal, wherein the neuregulin or neuregulin analog is a neuregulin isoform or a polypeptide comprising a neuregulin EGF domain.
法律状态
(US20170189489) LEGAL DETAILS FOR US2017189489  Actual or expected expiration date=2019-12-21    Legal state=ALIVE    Status=PENDING     Event publication date=2016-08-12  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US15236302  Application date=2016-08-12  Standardized application number=2016US-15236302     Event publication date=2016-08-12  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: AUDET, MAURY A    Event publication date=2016-08-12  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1675     Event publication date=2016-08-12  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: 11748-064-999 Customer Nbr: 20583    Event publication date=2016-08-12  Event code=US/ENT  Event type=Administrative notifications  Business Entity Status: SMALL    Event publication date=2016-08-12  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=2016-08-12  Event code=US/APST  Event indicator=Pos  Event type=Examination events  PAIR Application Status    Event publication date=2016-08-12  Event code=US/ENTYSTA  Event type=Administrative notifications  Entity Status Set to Undiscounted    Event publication date=2016-08-24  Event code=US/APPFILEREC  Event type=Administrative notifications  Event type=OAO  Filing Receipt    Event publication date=2016-08-24  Event code=US/APPINC  Event type=Examination events  Event type=OAO  Notice Mailed--Application Incomplete--Filing Date Assigned    Event publication date=2016-08-24  Event code=US/SMALL  Event type=Administrative notifications  Appl Has Filed a Verified Statement of Micro to Small Entity Status    Event publication date=2017-03-23  Event code=US/PTARDY  Event indicator=Pos  Event type=Examination events  Patent Term Adjustment - Ready for Examination    Event publication date=2017-03-27  Event code=US/RECEIPTUP  Event type=Administrative notifications  Event type=OAO  Filing Receipt - Updated    Event publication date=2017-03-28  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner in GAU    Event publication date=2017-04-03  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2017-07-06  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2017189489  Publication stage Code=A1  Publication date=2017-07-06  Standardized publication number=US20170189489     Event publication date=2017-07-06  Event code=US/PGPUBN  Event indicator=Pos  Event type=Examination events  Event type=OAO  PG-Pub Issue Notification
专利类型码
A1
国别省市代码
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