Injectable compositions for the controlled delivery of pharmacologically active compound. 机翻标题: 暂无翻译,请尝试点击翻译按钮。

源语言标题
(MX2004PA003608) Composiciones inyectables para el suministro controlado de compuesto farmacologicamente activo.
公开号/公开日
MXPA04003608 A 2004-07-27 [MX2004PA003608] / 2004-07-27
申请号/申请日
2004MX-PA03608 / 2004-04-16
发明人
SUVA ROBERT;
申请人
IDEXX LABORATORIES;
主分类号
IPC分类号
A61K-009/00A61K-009/10A61K-031/137A61K-031/138A61K-031/165A61K-031/18A61K-031/245A61K-031/4704A61K-031/496A61K-031/505A61K-031/65A61K-031/7036A61K-031/7048A61K-047/10A61K-047/12A61K-047/14A61K-047/20A61K-047/22A61K-047/26A61K-047/32A61
摘要
(MX2004PA003608) The present invention provides compositions and methods for extending the release times and lowering the toxicity of pharmacologically active compounds.  The compounds comprise a salt of the pharmacologically active compound with a lipophilic counterion and a pharmaceutically acceptable water soluble solvent combined together to form an injectable composition.  The lipophilic counterion may be a saturated or unsaturated C8-C22 fatty acid, and preferably may be a saturated or unsaturated C10-C18 fatty acid.  When injected into a mammal, at least a portion of the composition precipitates and releases the active compound over time.  Thus, the composition forms a slowly releasing drug depot of the active compound in the mammal.  Therefore, the present invention enables one to provide a controlled dose administration of the active compound for a periods of up to 15 days or even longer.  Many compounds can be administered according to the present invention including, but not limited to, tilmicosin, oxytetracycline, metoprolol, fluoxetine, roxithromycin, and turbinafine.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2001US-60343625 2001-10-19
主权利要求

        
法律状态
(MX2004PA003608) LEGAL DETAILS FOR MXPA04003608  Actual or expected expiration date=2024-04-16    Legal state=ALIVE    Status=GRANTED     Event publication date=2004-04-16  Event code=MX/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=MX MXPA04003608  Application date=2004-04-16  Standardized application number=2004MX-PA03608     Event publication date=2004-07-27  Event code=MX/A  Event type=Examination events  Patent application  Publication country=MX  Publication number=MXPA04003608  Publication stage Code=A  Publication date=2004-07-27  Standardized publication number=MX2004PA003608     Event publication date=2007-05-11  Event code=MX/FG  Event indicator=Pos  Event type=Event indicating In Force  Grant or registration Concesion
专利类型码
A
国别省市代码
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