Method of monitoring biofouling in membrane separation systems 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2004115757 A1 2004-06-17 [US20040115757] / 2004-06-17
申请号/申请日
2003US-10721667 / 2003-11-25
发明人
HO BOSCO P;WU MAY W;ZEIHER E H KELLE;CHATTORAJ MITA;
申请人
NALCO;
主分类号
IPC分类号
A01N-001/00A01N-001/02B01D-065/02B01D-065/10C02FC12Q-001/02C12Q-001/04G01N-021/78G01N-033/18
摘要
(US20040115757) Methods for monitoring and/or controlling biofouling in membrane separation systems are provided.  The present invention utilizes measurable amounts of fluorogenic agent(s) added to a feed stream to monitor and/or control the level of microbial growth during membrane separation and, thus, the purification of such feed stream during membrane separation.
机翻摘要
暂无翻译结果,您可以尝试点击头部的翻译按钮。
地址
代理人
代理机构
;
优先权号
2002US-10201088 2002-07-23 2003US-10721667 2003-11-25
主权利要求
(US20040115757) 1. A method of monitoring biofouling in a reverse osmosis membrane separation system including a reverse osmosis membrane capable of separating a feed stream into at least a first stream and a second stream comprising the steps of:providing a fluorogenic agent;  adding the fluorogenic agent to the feed stream;  providing a fluorometer to detect the fluorescent signal of the fluorogenic agent in at least one of the feed stream, the first stream and the second stream;  reacting the fluorogenic agent with at least one microorganism within the reverse osmosis membrane separation system;  forming a reacted fluorogenic agent;  using the fluorometer to measure the fluorescent signal of at least one of the fluorogenic agent and the reacted fluorogenic agent in at least one of the first stream and the second stream and optionally the feed stream;  and monitoring biofouling in the reverse osmosis membrane separation system based on the change in the signal of the fluorogenic agent, or the reacted fluorogenic agent or a combination of both signals measured. 2. The method of claim 1 wherein the membrane separation system is selected from the group consisting of a cross-flow reverse osmosis membrane separation system and a dead-end flow reverse osmosis membrane separation system. 3. The method of claim 1 wherein the fluorogenic agent is selected from the group consisting of acetic acid ester of pyrene 3,6,8-trisulfonic acid;  carboxyfluorescein diacetate;  3-carboxyumbelliferyl beta -D-galactopyranoside;  3-carboxyumbelliferyl beta -D-glucuronide;  9H-(1,3-dichloro-9,0-dimethylacridine-2-one-7-yl), D-glucuronide;  9H-(1,3-dichloro-9,9-dimethylacridin-2-one-7-yl);  resorufin beta -D-galactopyranoside;  fluorescein di-beta -D-galactopyranoside;  fluorescein di-beta -D-glucuronide;  resorufin beta -D-glucuronide;  fluorescein diphosphate;  resazurin;  resazurin, sodium salt;  4-methylumbelliferyl phosphate;  4-methylumbelliferyl beta -D-glucuronide;  pyranine phosphate;  pyrene 3,6,8-trisulfonic acid 1-phosphate;  and combinations thereof. 4. The method of claim 1 wherein the fluorogenic agent is selected from the group consisting of resazurin, 4-methylumbelliferyl phosphate, pyranine phosphate and combinations thereof. 5. The method of claim 1 wherein the fluorogenic agent is resazurin. 6. The method of claim 1 wherein the fluorogenic agent is added into the feed stream in an amount from about 5 ppt to 500 ppm. 7. The method of claim 1 wherein the fluorogenic agent is added into the feed stream in an amount from about 0.5 ppb to 5 ppm. 8. The method of claim 1 wherein the fluorogenic agent is added into the feed stream in an amount from about 5 ppb to about 500 ppb. 9. The method of claim 1 wherein biofouling is monitored by determining a ratio of the fluorescent signal of the reacted fluorogenic agent to the fluorescent signal of the fluorogenic agent in at least one of the first stream and the second stream. 10. The method of claim 9 further comprisingdetermining the rate of change of the ratio of the fluorescent signal of the reacted fluorogenic agent to the fluorescent signal of the fluorogenic agent in at least one of the first stream and the second stream to monitor biofouling. 11. The method of claim 1 further comprising the step of:determining the optimal amount of biocontrol treatment based on the change in the signal of the fluorogenic agent, or the reacted fluorogenic agent, or a combination of both signals measured;  and applying the optimal amount of biocontrol treatment to the membrane separation system. 12. The method of claim 11 wherein the biocontrol treatment is selected from the group consisting of biocides, biocontrol agents, biocontrol methods and combinations thereof. 13. The method of claim 12 wherein the biocides are selected from the group consisting of oxidizing biocides, non-oxidizing biocides and combinations thereof. 14. The method of claim 12 wherein the biocontrol agents are selected from the group consisting of bio-dispersants, bio-detergents, chaotropic agents, surfactants, chelating agents, enzymatic cleaners and combinations thereof. 15. The method of claim 12 wherein the biocontrol methods are selected from the group consisting of ultrasound, electric fields and air backwashes. 16. The method of claim 1 wherein the microorganisms are selected from the group consisting of planktonic microorganisms, sessile microorganisms and combinations thereof. 17. The method of claim 1 further comprising the addition of an inert fluorescent tracer to the feed stream to monitor biofouling in the membrane separation system based on the change in the signal of the fluorogenic agent or the reacted fluorogenic agent relative to the signal of the inert fluorescent tracer.
法律状态
(US20040115757) LEGAL DETAILS FOR US2004115757  Actual or expected expiration date=2009-04-13    Legal state=DEAD    Status=LAPSED     Event publication date=2003-11-25  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US72166703  Application date=2003-11-25  Standardized application number=2003US-10721667     Event publication date=2003-11-25  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: FERNANDEZ, SUSAN EMILY    Event publication date=2003-11-25  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1651     Event publication date=2003-11-25  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: 7593-CO1    Event publication date=2003-11-25  Event code=US/ENT  Event type=Administrative notifications  Entity Status Set to Undiscounted Business Entity Status: UNDISCOUNTED    Event publication date=2003-11-25  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=2003-11-25  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2004-03-18  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2004-04-21  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=2004-06-17  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2004115757  Publication stage Code=A1  Publication date=2004-06-17  Standardized publication number=US20040115757     Event publication date=2004-09-15  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=2005-01-13  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=2005-04-18  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2005-10-19  Event code=US/AINEA  Event type=OAI  Event type=Examination events  Informal or Non-Responsive Amendment after Examiner Action    Event publication date=2005-10-19  Event code=US/CTNFR  Event type=Examination events  Event type=OAI  Response after Non-Final Action    Event publication date=2005-10-19  Event code=US/136G  Event type=OAO  Request for Extension of Time - Granted    Event publication date=2005-11-28  Event code=US/CTNFR  Event type=Examination events  Event type=OAI  Response after Non-Final Action    Event publication date=2006-02-06  Event code=US/CTFR  Event type=Examination events  Event type=OA  Event type=OAO  Final Rejection    Event publication date=2006-08-02  Event code=US/RCEX  Event type=Examination events  Event type=RCE  Event type=OAI  Request for Continued Examination (RCE)    Event publication date=2006-08-31  Event code=US/DRCECAP  Event type=RCE  Event type=OAO  Disposal for a RCE / CPA / R129    Event publication date=2006-09-18  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2006-12-18  Event code=US/CTNFR  Event type=Examination events  Event type=OAI  Response after Non-Final Action    Event publication date=2007-03-02  Event code=US/CTFR  Event type=Examination events  Event type=OA  Event type=OAO  Final Rejection    Event publication date=2007-05-24  Event code=US/DC  Event indicator=Neg  Event type=Examination events  Terminal Disclaimer Filed    Event publication date=2007-05-24  Event code=US/RCEX  Event type=Examination events  Event type=RCE  Event type=OAI  Request for Continued Examination (RCE)    Event publication date=2007-06-01  Event code=US/DRCECAP  Event type=RCE  Event type=OAO  Disposal for a RCE / CPA / R129    Event publication date=2007-08-17  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2007-11-15  Event code=US/CTNFR  Event type=Examination events  Event type=OAI  Response after Non-Final Action    Event publication date=2007-11-20  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment  Effective date of the event=2002-07-23  CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE TO ONDEO NALCO COMPANY, ONDEO NALCO CENTER, NAPERVILLE, IL 60563-1198 PREVIOUSLY RECORDED ON  REEL 014853 FRAME 0304 ASSIGNORS:HO, BOSCO P. WU, MAY W. ZEIHER, E. H. KELLE AND OTHERS REEL/FRAME:020136/0699     Event publication date=2007-11-21  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment  Effective date of the event=2003-11-04  CHANGE OF NAME ASSIGNOR:ONDEO NALCO COMPANY REEL/FRAME:020144/0167     Event publication date=2008-03-11  Event code=US/CTFR  Event type=Examination events  Event type=OA  Event type=OAO  Final Rejection    Event publication date=2008-05-19  Event code=US/RCEX  Event type=Examination events  Event type=RCE  Event type=OAI  Request for Continued Examination (RCE)    Event publication date=2008-06-07  Event code=US/DRCECAP  Event type=RCE  Event type=OAO  Disposal for a RCE / CPA / R129    Event publication date=2008-09-26  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2009-04-13  Event code=US/ABNOA  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=OAO  Abandoned -- Failure to Respond to an Office Action
专利类型码
A1
国别省市代码
若您需要申请原文,请登录。

最新评论

暂无评论。

登录后可以发表评论

意见反馈
返回顶部