公开号/公开日

US2015218605 A1 2015-08-06 [US20150218605] / 2015-08-06

申请号/申请日

2015US-14687025 / 2015-04-15

发明人

HOSHINO YASUSHI;MIYAGAWA YUKIKO;SHIRAGA SEIZABURO;

申请人

AJINOMOTO;

主分类号

IPC分类号

C12P-013/08

摘要

(US20150218605) A method for producing an L-amino acid using a fatty acid as the carbon source is provided.  An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been introduced with the lcfA gene, in a medium containing a fatty acid, and collecting the L-amino acid from the medium.

机翻摘要

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地址

代理人

代理机构

;

优先权号

2012JP-0231582 2012-10-19 2013WO-JP78373 2013-10-18

主权利要求

(US20150218605) 1. A method for producing an L-aminoacid comprising: culturing a bacterium belonging to the family Enterobacteriaceae and having an L-aminoacid-producing ability in a medium comprising a fatty acid; and collecting the L-aminoacid from the medium, wherein the bacterium is a bacterium introduced with the lcfA gene, and the lcfA gene is a DNA selected from the group consisting of: (A) a DNA encoding a protein comprising the aminoacid sequence of SEQ ID NO: 18; (B) a DNA encoding a protein comprising the aminoacid sequence of SEQ ID NO: 18 including substitution, deletion, insertion, or addition of one or several aminoacid residues, and having an activity of generating a fatty acyl-CoA from a long chain fatty acid, and taking it up through the inner membrane; (C) a DNA comprising the nucleotide sequence of SEQ ID NO: 17; and (D) a DNA hybridizable under stringent conditions with a nucleotide sequence complementary to the nucleotide sequence of SEQ ID NO: 17, or with a probe that can be prepared from the nucleotide sequence, and encoding a protein having an activity of generating a fatty acyl-CoA from a long chain fatty acid, and taking it up through the inner membrane.

法律状态

(US20150218605) LEGAL DETAILS FOR US2015218605  Actual or expected expiration date=2016-07-12    Legal state=DEAD    Status=LAPSED     Event publication date=2015-04-15  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US14687025  Application date=2015-04-15  Standardized application number=2015US-14687025     Event publication date=2015-04-15  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: STEADMAN, DAVID J    Event publication date=2015-04-15  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1656     Event publication date=2015-04-15  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: US-533 Customer Nbr: 38108    Event publication date=2015-04-15  Event code=US/ENT  Event type=Administrative notifications  Business Entity Status: UNDISCOUNTED    Event publication date=2015-04-15  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=2015-04-15  Event code=US/PTARDY  Event indicator=Pos  Event type=Examination events  Patent Term Adjustment - Ready for Examination    Event publication date=2015-04-15  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2015-04-15  Event code=US/ENTYSTA  Event type=Administrative notifications  Entity Status Set to Undiscounted    Event publication date=2015-04-27  Event code=US/APPFILEREC  Event type=Administrative notifications  Event type=OAO  Filing Receipt    Event publication date=2015-05-15  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: AJINOMOTO CO., INC., JAPAN ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:HOSHINO, YASUSHI MIYAGAWA, YUKIKO SHIRAGA, SEIZABURO SIGNING DATES FROM 20150507 TO 20150508 REEL/FRAME:035647/0854     Event publication date=2015-05-18  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2015-06-23  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner in GAU    Event publication date=2015-07-08  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2015-08-06  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2015218605  Publication stage Code=A1  Publication date=2015-08-06  Standardized publication number=US20150218605     Event publication date=2015-08-06  Event code=US/PGPUBN  Event indicator=Pos  Event type=Examination events  Event type=OAO  PG-Pub Issue Notification    Event publication date=2015-10-27  Event code=US/CTFR  Event type=Examination events  Event type=OA  Event type=OAO  Final Rejection    Event publication date=2016-03-03  Event code=US/CTAV  Event type=OAO  Advisory Action (PTOL-303)    Event publication date=2016-04-06  Event code=US/CTAV  Event type=OAO  Advisory Action (PTOL-303)    Event publication date=2016-07-12  Event code=US/ABNOA  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=OAO  Abandoned -- Failure to Respond to an Office Action

专利类型码

A1

国别省市代码

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