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公开号/公开日
US2014154135 A1 2014-06-05 [US20140154135] US9241491 B2 2016-01-26 [US9241491] / 2014-06-05 2016-01-26
申请号/申请日
2013US-14085924 / 2013-11-21
发明人
BERENTSVEIG VLADIMIR; ERICKSON GARY; WEINBERGER RON
申请人
SABAN VENTURES
主分类号
IPC分类号
A01N-025/06;A01N-059/00;A61L-002/00;A61L-002/06;A61L-002/16;A61L-002/20;A61L-002/22;A61L-002/24;A61L-009/00;A62B-007/08;C01B-015/013
摘要
(US9241491)
A nebulant suitable for sterilization comprising finely divided liquid droplets suspended in a gas, said droplets including a solute, which is advantageously hydrogen peroxide and a solvent, for example water, wherein the droplets have a concentration of greater than 60 wt % of solute and an average diameter of less than 1.0 micron, preferably less than 0.8 microns. 
Sterilization using the nebulant may be carried out in suitably adapted apparatus by nebulizing a solution comprising a sterilizing agent in a solvent to form a nebulant of finely divided particles of the solution in a gas stream, said solution including a solvent having a lower boiling point than the sterilizing agent; subjecting the nebulant to energy of a kind and for a duration sufficient to vaporize solvent in preference to sterilizing agent, whereby to increase the concentration of the agent in the nebulant particles; removing the solvent vaporized from the gas stream at or above atmospheric pressure and, if necessary, cooling the nebulant to below 70° C.; and exposing a surface to be sterilized to the nebulant of concentrated sterilizing agent for a time sufficient to sterilize the surface.
机翻摘要
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地址
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代理机构
优先权号
2005AU-0904181 2005-08-04 2005AU-0904196 2005-08-04 2005AU-0904198 2005-08-04 2006AU-0900748 2006-02-15 2006WO-AU01113 2006-08-04 2008US-11997855 2008-02-04 2013US-14085924 2013-11-21
主权利要求
(US9241491)
What is claimed is:
1. 
A method for disinfecting or sterilizing a surface comprising the steps of: (1) nebulising a solution comprising a sterilizing agent in a solvent to form a nebulant of finely divided particles of the solution in a gas stream, said solution including a solvent having a lower boiling point than the sterilizing agent; 

(2) subjecting the nebulant to energy of a kind and for a duration sufficient to vaporize solvent in preference to sterilizing agent to increase the concentration of the sterilizing agent in the nebulant particles; 

(3) removing solvent vaporized in step (2) from the gas stream at or above atmospheric pressure and, optionally cooling the nebulant to below 70 deg. C.; and 

(4) exposing said surface to the nebulant of concentrated sterilizing agent from step (3) for a time sufficient to disinfect or sterilize the surface.
2. A method according to claim 1 wherein steps (1) to (4) are conducted at atmospheric pressure or above.
3. A method according to claim 2 wherein the surface is a mated surface or a lumen and wherein a 6 log reduction in micro-organism load in a mated surface sterilization test or a lumen sterilization test is achieved within 20 minutes exposure time to the nebulant from step (3) at atmospheric pressure.
4. A method according to claim 3 wherein a 6 log reduction in micro-organism load in a mated surface sterilization test is achieved within 10 minutes exposure time to the nebulant from step (3) at atmospheric pressure.
5. A method according to claim 1 wherein the sterilizing agent is selected from the group consisting of hydrogen peroxide, peracetic acid, and mixtures thereof.
6. A method according to claim 1 wherein the solvent is, or includes, water.
7. A method according to claim 6 wherein the solution in step (1) is 35% or less hydrogen peroxide in water.
8. A method according to claim 7 wherein water vapour is removed from the gas stream at or above atmospheric pressure in step (3) by a cold trap or condenser, a molecular sieve or desiccant, a semipermeable membrane device, or other water removal means operable at or above atmospheric pressure, while leaving the particles of concentrated peroxide solution in suspension in the gas stream.
9. A method according to claim 6 wherein step (2) includes heating the nebulant.
10. A method according to claim 9 wherein the nebulant is heated during passage over a heating element, which transfers sufficient energy to the solution particles to vaporize water therefrom.
11. A method according to claim 1 wherein the nebulising of step (1) is conducted with an ultrasonic transducer.
12. A method according to claim 1 wherein in step (3), the sterilizing agent concentration in the nebulant increases to 60% to 80% while the particles shrink to an average diameter of less than 1 micron.
13. A method according to claim 12 wherein the particles shrink to an average diameter of less than 0.8 micron.
14. A method according to claim 1 wherein the surface is exposed to nebulant from step (3) for a time sufficient to sterilize the surface.
15. Apparatus for disinfecting or sterilizing a surface comprising: (1) means adapted to produce a nebulant comprising finely divided particles of a solution suspended in a gas, the solution comprising a solute and a solvent; 

(2) means for supplying sufficient energy to the nebulant to selectively flash off at least some of the solvent as a vapour, whereby the concentration of solute in nebulant particles is increased; 

(3) means to separate solvent vapour from the nebulant after at atmospheric pressure, and optionally means for cooling the nebulant to below 70 deg. C.; and 

(4) means for exposing the surface to be disinfected or sterilized to the nebulant obtained from the solvent vapour separation means (3).
16. Apparatus according to claim 15 further comprising means for controlling the energy supplied to the nebulant, to ensure that solvent is vaporised in preference to solute.
17. Apparatus according to claim 16 wherein the means for nebulization are selected from the group comprising ultrasonic nebulizers, sprays, jet nebulizers and piezoelectric nebulizers, operated continuously or cyclically.
18. Apparatus according to claim 17 wherein the nebulizers are switched on and off cyclically.
19. Apparatus according to claim 16 wherein the means for supplying sufficient energy to the nebulant is by means selected from a heating element; infrared, laser, microwave, RF or other radiation generating means; induction heating means; heat exchanger; conduction means; convection means; and mechanical energy transfer means.
20. Apparatus according to claim 15 wherein the step of vapour removal is carried out by means selected from means for passing the gas through a drying agent, desiccant, or through suitable molecular sieves, membranes, means for passage through a centrifuge, and means of a suitable cyclonic separator.
法律状态
(US9241491)
LEGAL DETAILS FOR US2014154135

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专利类型码
A1 B2
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