Amblyomma maculatum-associated rickettsiae in vector tissues and vertebrate hosts during tick feeding 机翻标题: 暂无翻译,请尝试点击翻译按钮。

来源
Experimental & applied acarology
年/卷/期
2019 / 77 / 2
页码
187-205
ISSN号
0168-8162
作者单位
Mississippi State Univ, Inst Imaging & Analyt Technol, Mississippi State, MS 39762 USA;Mississippi State Univ, Lab Anim Resources, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Pathobiol & Populat Med, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA;
作者
Lawrence, Amanda M.;Willeford, Bridget V.;Varela-Stokes, Andrea S.;Lee, Jung Keun;Moraru, Gail M.;Stokes, John V.;Benton, Amanda N.;Wills, Robert W.;Nabors, Haley P.;Smith, Catherine L.;
摘要
Rickettsia parkeri, a causative agent of spotted fever rickettsiosis, is transmitted by Amblyomma maculatum (Gulf Coast tick), a tick that may also carry a non-pathogenic spotted fever group Rickettsia, Candidatus Rickettsia andeanae. Here, we evaluated R. parkeri and Candidatus R. andeanae in tissues from A. maculatum prior to, during, and after blood feeding on rabbits. Using colony-reared A. maculatum that were capillary-fed uninfected cells, R. parkeri, Candidatus R. andeanae, or both rickettsiae, we detected higher levels of Rickettsia spp. in the respective treatment groups. Rickettsial levels increased during blood feeding for both R. parkeri and Candidatus R. andeanae, with a greater increase in R. parkeri in co-infected ticks compared to singly-infected ticks. We detected transovarial transmission of Candidatus R. andeanae in egg and larval cohorts and confirmed vertical transmission of R. parkeri in one group of larvae. Rabbits from all Rickettsia-exposed groups seroconverted on immunofluorescent antibody testing using R. parkeri antigen. Visualization of Candidatus R. andeanae in tick salivary glands suggested potential transmission via tick feeding. Here, rickettsial levels in artificially infected ticks demonstrate changes during feeding and transovarial transmission that may be relevant for interpreting rickettsial levels detected in wild A. maculatum.
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关键词/主题词
Rickettsia parkeri;"Candidatus Rickettsia andeanae";Gulf Coast tick;Tick-feeding;
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