Carotenoid Compound Coming From Plant And Containing Natural Astaxanthin, Preparation Method Therefor, And Composition 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2016331699 A1 2016-11-17 [US20160331699] / 2016-11-17
申请号/申请日
2014US-15024783 / 2014-09-23
发明人
XU XINDE;SHAO BIN;PENG YONGJIAN;WANG SHENGNAN;
申请人
ZHEJIANG MEDICINE;
主分类号
IPC分类号
A61K-031/122A61K-036/71C07C-403/24
摘要
(US20160331699) The present invention provides a high-content carotenoid compound from adonis amurensis.  The content of the total carotenoid of the carotenoid compound is greater than 95%.  The content of all-trans (3S, 3′S)-carotenoid is greater than 80%.  The carotenoid crystals have a high purity, and can be used in multiple forms in the fields of a dietary supplement of a human being, a food additive, a feed additive and a cosmetic product.  In addition, the present invention also provides a method for manufacturing the compound.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2013CN-0440119 2013-09-24 2014WO-CN00862 2014-09-23
主权利要求
(US20160331699) We claim: 1.  A high-content carotenoid compound from flower, stem and fruit of adonis amurensis, characterized in that, the content of the total carotenoid in the high-content carotenoid compound is higher than 95 wt %, wherein the proportion of all-trans (3S, 3'S)-astaxanthin in the total carotenoid is higher than 80 wt %, the all-trans (3S, 3'S)-astaxanthin has the molecular structure as shown in formula (I):   00007 2. The high-content carotenoid compound according to claim 1, characterized in that, the total carotenoid comprises semi-astacene, astacene and adonirubin. 3. The high-content of carotenoid compound according to claim 2, characterized in that, the proportion of the total content of semi-astancene and astacene in the total carotenoid is less than 10 wt %, and the proportion of adonirubin in the total carotenoid is less than 10 wt %. 4. A composition comprising the high-content carotenoid compound according to claim 1. 5. The composition according to claim 4, characterized in that, further comprising one or more of vegetable oil, modified starch, sucrose, dextrin and gelatin. 6. A composition comprising the high-content carotenoid compound according to claim 2. 7. The composition according to claim 6, further comprising one or more of vegetable oil, modified starch, sucrose, dextrin and gelatin. 8. A composition comprising the high-content carotenoid compound according to claim 3. 9. The composition according to claim 8, further comprising one or more of vegetable oil, modified starch, sucrose, dextrin and gelatin. 10. A method of preparing a high-content carotenoid compound by using adonis amurensis extract as raw material comprising the steps of: (a) mixing Adonis amurensis extract with alcohol(s) solvent and fully dissolving, to obtain a mixed solution;   (b) heating the mixed solution of step (a) to 25.about.75 deg. C., and dropwise adding an alkali solution to the reaction, and the reaction time is 0.5.about.6.0 hr;   (c) adding a mixture of alcohols solvent and water to obtain a reaction solution, after completion of step (b);   (d) filtering the reaction solution of step (c) to obtain a filter cake, and then washing the filter cake with a mixture of alcohols solvent and water; and   (e) drying the filter cake of step (d) in vacuum to obtain a carotenoid compound;   wherein, in the high-content carotenoid compound, the content of the total carotenoid is higher than 95 wt %, the proportion of the all-trans (3S, 3'S) astaxanthin in the carotenoid is higher than 80 wt %, the all-trans (3S, 3'S)-astaxanthin has the molecular structure as shown in formula (I):    11. The method according to claim 10, characterized in that, in step (a), the ratio of the volume of the alcohols solvent to the weight of Adonis amurensis extract is 5.about.50 times, preferably, the ratio of the volume of the alcohols solvent to the weight of Adonis amurensis extract is 25.about.40 times. 12. The method according to claim 10, characterized in that, in step (b), the concentration of the alkali solution of the reaction is 0.01.about.2.50 mol/L after adding dropwise the alkali solution, preferably is 1.00.about.2.00 mol/L. 13. The method according to claim 10, characterized in that, the alcohols solvent in step (a) is ethanol, propylene glycol or glycerol; and the alkali solution in step (b) is sodium hydroxide solution, potassium hydroxide solution or sodium methoxide solution. 14. The method according to claim 10, characterized in that, the volume ratio of the alcohols solvent to water in step (c) is 1:5.about.10; and the volume ratio of the alcohols solvent to water in the step (d) is 2.about.3:1.
法律状态
(US20160331699) LEGAL DETAILS FOR US2016331699  Actual or expected expiration date=2034-09-23    Legal state=ALIVE    Status=PENDING     Event publication date=2014-09-23  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US15024783  Application date=2014-09-23  Standardized application number=2014US-15024783     Event publication date=2016-11-17  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2016331699  Publication stage Code=A1  Publication date=2016-11-17  Standardized publication number=US20160331699
专利类型码
A1
国别省市代码
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