(CN105968402) 本发明涉及种以Pickering高内相乳液为模板制备的3D多孔支架材料及其制备方法。本发明以明胶纳米颗粒为乳液稳定剂,水为连续相,有机溶剂为分散相,将可聚合的功能单体、引发剂和交联剂溶于连续相,采用均质乳化形成水包油型(O/W)Pickering高内相乳液,再通过聚合反应制得3D多孔支架材料。本发明制备的3D多孔支架材料不仅具有较高的孔隙率和丰富的多层次孔道结构,而且具有良好的机械性能和生物相容性,可作为细胞培养支架广泛用于生物医学材料领域。
(CN105968402) 1. As a template to Pickering high internal phase emulsion A prepared 3D porous scaffold material, characterized in prepared by: Formulated (1) with water, gelatin nanoparticles, functional monomers, initiator and a crosslinking agent consisting of a continuous phase, wherein the gelatin nanoparticles and a functional monomer concentration range being 5-15 mg/mL and a 2.5-5.0 mol/L ; (2) at 9000-20000 rpm and stirring 1:3 volume ratio in accordance with the continuous and disperse-mixed to form O/W Pickering 1:9 type high internal phase emulsion 15 minutes and the resultant product was hermetically sealed with nitrogen ; (3), is reacted under conditions again at 50 Ć 24-48 hours 24 hours with water and ethanol are alternately extracted ; (4), to give the 3D porous scaffold samples were finally freeze-dried material.
(CN105968402) LEGAL DETAILS FOR CN105968402 Actual or expected expiration date=2036-06-07 Legal state=ALIVE Status=PENDING Event publication date=2016-06-07 Event code=CN/APP Event indicator=Pos Event type=Examination events Application details Application country=CN CN201610392975 Application date=2016-06-07 Standardized application number=2016CN-0392975 Event publication date=2016-09-28 Event code=CN/A Event type=Examination events Published application Publication country=CN Publication number=CN105968402 Publication stage Code=A Publication date=2016-09-28 Standardized publication number=CN105968402 Event publication date=2016-09-28 Event code=CN/C06 Event indicator=Pos Event type=Examination events Publication Event publication date=2016-10-26 Event code=CN/C10 Event type=Examination events Request of examination as to substance
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