一种​以​Pickering​高​内​相​乳液​为​模板​制备​的​3D​多孔​支架​材料

源语言标题
(CN105968402) 一种​以​Pickering​高​内​相​乳液​为​模板​制备​的​3D​多孔​支架​材料
公开号/公开日
CN105968402 A 2016-09-28 [CN105968402] / 2016-09-28
申请号/申请日
2016CN-0392975 / 2016-06-07
发明人
TAN HUAN;WEI TAO;LIN WEI;MU CHANGDAO;WEI JINGJING;
申请人
CHENGDU UNIVERSITY;
主分类号
IPC分类号
C08F-220/56C08F-220/58C08F-289/00C08J-009/28C12N-005/00
摘要
(CN105968402) 本​发明​涉及​种​以​Pickering​高​内​相​乳液​为​模板​制备​的​3D​多孔​支架​材料​及其​制备​方法。本​发明​以​明胶​纳米​颗粒​为​乳液​稳定剂,水​为​连续​相,有机​溶剂​为​分散相,将​可​聚合​的​功能​单体、引发​剂​和​交​联​剂​溶于​连续​相,采用​均质​乳化​形成​水​包​油​型(O/W)Pickering​高​内​相​乳液,再通过​聚合反应​制得​3D​多孔​支架​材料。本​发明​制备​的​3D​多孔​支架​材料​不仅​具有​较高​的​孔隙​率​和​丰富​的​多层次​孔道​结构,而且​具有​良好​的​机械性能​和​生物​相容性,可作​为​细胞培养​支架​广泛​用于​生物​医学​材料​领域。
地址
代理人
代理机构
;
优先权号
2016CN-0392975 2016-06-07
主权利要求
(CN105968402) 1. As a template to Pickering high internal phase emulsion A prepared 3D porous scaffold material, characterized in prepared by: Formulated (1) with water, gelatin nanoparticles, functional monomers, initiator and a crosslinking agent consisting of a continuous phase, wherein the gelatin nanoparticles and a functional monomer concentration range being 5-15 mg/mL and a 2.5-5.0 mol/L ; (2) at 9000-20000 rpm and stirring 1:3 volume ratio in accordance with the continuous and disperse-mixed to form O/W Pickering 1:9 type high internal phase emulsion 15 minutes and the resultant product was hermetically sealed with nitrogen ; (3), is reacted under conditions again at 50 Ć 24-48 hours 24 hours with water and ethanol are alternately extracted ; (4), to give the 3D porous scaffold samples were finally freeze-dried material.
法律状态
(CN105968402) LEGAL DETAILS FOR CN105968402  Actual or expected expiration date=2036-06-07    Legal state=ALIVE    Status=PENDING     Event publication date=2016-06-07  Event code=CN/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=CN CN201610392975  Application date=2016-06-07  Standardized application number=2016CN-0392975     Event publication date=2016-09-28  Event code=CN/A  Event type=Examination events  Published application  Publication country=CN  Publication number=CN105968402  Publication stage Code=A  Publication date=2016-09-28  Standardized publication number=CN105968402     Event publication date=2016-09-28  Event code=CN/C06  Event indicator=Pos  Event type=Examination events  Publication    Event publication date=2016-10-26  Event code=CN/C10  Event type=Examination events  Request of examination as to substance
专利类型码
A
国别省市代码
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