公开号/公开日

AU2015372560 A1 2017-07-20 [AU2015372560] / 2017-07-20

申请号/申请日

2015AU-0372560 / 2015-12-23

发明人

GELLER BRUCE L;GREENBERG DAVID;

申请人

OREGON STATE UNIVERSITY;UNIVERSITY OF TEXAS;

主分类号

IPC分类号

A61K-048/00C07F-009/6533C07H-019/16

摘要

(AU2015372560) Provided are antisense oligonucleotides targeted against bacterial genes involved in biochemical pathways and/or cellular processes, and related compositions and methods of using the oligonucleotides and compositions, alone or in combination with other antimicrobial agents, for instance, in the treatment of an infected mammalian subject.  Embodiment's of the present disclosure relate, in part, to the discovery that the antisense targeting of bacterial genes involved in biochemical pathways and/or cellular processes can, inter alia, increase the antibiotic susceptibility of otherwise antibiotic-resistant pathogenic bacteria, and reduce the ability of certain pathogenic bacteria to grow.

机翻摘要

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地址

代理人

代理机构

;

优先权号

2014US-62098713 2014-12-31 2015WO-US00280 2015-12-23

主权利要求

法律状态

(AU2015372560) LEGAL DETAILS FOR AU2015372560  Actual or expected expiration date=2035-12-23    Legal state=ALIVE    Status=PENDING     Event publication date=2015-12-23  Event code=AU/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=AU AU2015372560  Application date=2015-12-23  Standardized application number=2015AU-0372560     Event publication date=2017-07-20  Event code=AU/A1  Event indicator=Pos  Event type=Examination events  Open to public inspection  Publication country=AU  Publication number=AU2015372560  Publication stage Code=A1  Publication date=2017-07-20  Standardized publication number=AU2015372560

专利类型码

A1

国别省市代码

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