Efficient mucosal vaccination mediated by the neonatal Fc receptor 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2016184425 A1 2016-06-30 [US20160184425] / 2016-06-30
申请号/申请日
2015US-14961938 / 2015-12-08
发明人
ZHU XIAOPING;YE LILIN;LU LI;
申请人
UNIVERSITY OF MARYLAND;
主分类号
IPC分类号
A61K-039/21A61K-039/245C07K-014/005C07K-014/315C07K-014/35C12N-007/00
摘要
(US20160184425) The present invention relates to methods and compositions for enhancing delivery of vaccine antigens to the mucosal epithelium, the composition comprising an antigen from an infectious agent fused with an Fc fragment of an immunoglobulin recognized by the neonatal receptors (FcRn).  The composition is effective in eliciting a protective long-term memory T cell immune response against infection at a distant mucosal site.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2011US-12932310 2011-02-23 2015US-14961938 2015-12-08
主权利要求
(US20160184425) 1. A vaccine comprising a fusion protein comprising an Fc fragment of an immunoglobulin recognized by the neonatal receptors (FcRn) in a subject fused to a desired antigen, wherein said vaccine is administered to a mucosal epithelium and i
法律状态
(US20160184425) LEGAL DETAILS FOR US2016184425  Actual or expected expiration date=2031-02-23    Legal state=ALIVE    Status=PENDING     Event publication date=2015-12-08  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US14961938  Application date=2015-12-08  Standardized application number=2015US-14961938     Event publication date=2015-12-08  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: LI, BAO Q    Event publication date=2015-12-08  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1648     Event publication date=2015-12-08  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: 001/446/SAP    Event publication date=2015-12-08  Event code=US/ENT  Event type=Administrative notifications  Business Entity Status: SMALL    Event publication date=2015-12-08  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=2015-12-08  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2015-12-08  Event code=US/ENTYSTA  Event type=Administrative notifications  Entity Status Set to Undiscounted    Event publication date=2015-12-22  Event code=US/APPFILEREC  Event type=Administrative notifications  Event type=OAO  Filing Receipt    Event publication date=2015-12-22  Event code=US/APPINC  Event type=Examination events  Event type=OAO  Notice Mailed--Application Incomplete--Filing Date Assigned    Event publication date=2015-12-22  Event code=US/SMALL  Event type=Administrative notifications  Appl Has Filed a Verified Statement of Micro to Small Entity Status    Event publication date=2016-02-03  Event code=US/PTARDY  Event indicator=Pos  Event type=Examination events  Patent Term Adjustment - Ready for Examination    Event publication date=2016-03-24  Event code=US/RECEIPTUP  Event type=Administrative notifications  Event type=OAO  Filing Receipt - Updated    Event publication date=2016-03-27  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner in GAU    Event publication date=2016-06-30  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2016184425  Publication stage Code=A1  Publication date=2016-06-30  Standardized publication number=US20160184425     Event publication date=2016-06-30  Event code=US/PGPUBN  Event indicator=Pos  Event type=Examination events  Event type=OAO  PG-Pub Issue Notification
专利类型码
A1
国别省市代码
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