(US9506094) 1. A method for producing an L-aminoacid comprising: (A) culturing a coryneform bacterium having an L-aminoacid producing ability in a medium; and (B) collecting the L-aminoacid from the medium, wherein the bacterium has been modified to increase the expression of a gene encoding a phosphate transporter, wherein the increased expression of the gene is obtained by increasing the copy number of the gene and/or modifying an expression control sequence of the gene, wherein said phosphate transporter is selected from the group consisting of: (a) a protein which comprises the aminoacid sequence of SEQ ID NO: 6 or SEQ ID NO: 26, (b) a protein which comprises all of SEQ ID NO: 6 or 26 except for the substitution, deletion, insertion or addition of 1 to 10 aminoacid residues, wherein said protein has phosphate transporter activity, (c) a protein which comprises all of SEQ ID NO: 6 or 26 except for the replacement of the aminoacid residue at a position corresponding to position 246 of SEQ ID NO: 6 with a serine residue, and (d) a protein which comprises all of SEQ ID NO: 6 or 26 except for (i) the replacement of the aminoacid residue at a position corresponding to position 246 of SEQ ID NO: 6 with a serine residue, and (ii) the substitution, deletion, insertion or addition of 1 to 10 aminoacid residues, wherein said protein has phosphate transporter activity. 7. A method for producing an L-aminoacid comprising: (A) culturing a coryneform bacterium having an L-aminoacid producing ability in a medium; and (B) collecting the L-aminoacid from the medium, wherein the bacterium has been modified to express a gene encoding a phosphate transporter, wherein said phosphate transporter is selected from the group consisting of: (a) a protein which comprises all of SEQ ID NO: 6 or 26 except for the replacement of the aminoacid residue at a position corresponding to position 246 of SEQ ID NO: 6 with a serine residue, and (b) a protein which comprises all of SEQ ID NO: 6 or 26 except for (i) the replacement of the aminoacid residue at a position corresponding to position 246 of SEQ ID NO: 6 with a serine residue, and (ii) the substitution, deletion, insertion or addition of 1 to 10 aminoacid residues, wherein said protein has phosphate transporter activity.
(US9506094) LEGAL DETAILS FOR US2015307907 Actual or expected expiration date=2034-05-13 Legal state=ALIVE Status=GRANTED Event publication date=2015-07-10 Event code=US/APP Event indicator=Pos Event type=Examination events Application details Application country=US US14796326 Application date=2015-07-10 Standardized application number=2015US-14796326 Event publication date=2015-07-10 Event code=US/EXMR Event type=Administrative notifications USPTO Examiner Name Primary Examiner: RAMIREZ, DELIA M Event publication date=2015-07-10 Event code=US/ART Event type=Administrative notifications USPTO Art Group ART=1652 Event publication date=2015-07-10 Event code=US/DK Event type=Examination events Attorney Docket Number Docket Nbr: US-513 Customer Nbr: 38108 Event publication date=2015-07-10 Event code=US/ENT Event type=Administrative notifications Business Entity Status: UNDISCOUNTED Event publication date=2015-07-10 Event code=US/AIA Event type=Administrative notifications First Inventor File Indicated: AIA=Yes Event publication date=2015-07-10 Event code=US/PTARDY Event indicator=Pos Event type=Examination events Patent Term Adjustment - Ready for Examination Event publication date=2015-07-10 Event code=US/PET Event type=APL Petition Entered Event publication date=2015-07-10 Event code=US/IDS Event type=Examination events Event type=OAI Information Disclosure Statement Filed Event publication date=2015-07-10 Event code=US/ENTYSTA Event type=Administrative notifications Entity Status Set to Undiscounted Event publication date=2015-07-22 Event code=US/APPFILEREC Event type=Administrative notifications Event type=OAO Filing Receipt Event publication date=2015-08-12 Event code=US/DOCK Event indicator=Pos Event type=Examination events Case Docketed to Examiner in GAU Event publication date=2015-09-11 Event code=US/AS Event type=Change of name or address Event type=Reassignment Assignment Owner: AJINOMOTO CO., INC., JAPAN Effective date of the event=2015-08-20 ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:HIRANO, SEIKO HAYASHI, KAZUYUKI REEL/FRAME:036538/0640 Event publication date=2015-09-14 Event code=US/IDS Event type=Examination events Event type=OAI Information Disclosure Statement Filed Event publication date=2015-10-29 Event code=US/A1 Event type=Examination events Application published Publication country=US Publication number=US2015307907 Publication stage Code=A1 Publication date=2015-10-29 Standardized publication number=US20150307907 Event publication date=2015-10-29 Event code=US/PGPUBN Event indicator=Pos Event type=Examination events Event type=OAO PG-Pub Issue Notification Event publication date=2016-01-12 Event code=US/CTNF Event type=Examination events Event type=OA Event type=OAO Non-Final Rejection Event publication date=2016-02-24 Event code=US/IDS Event type=Examination events Event type=OAI Information Disclosure Statement Filed Event publication date=2016-07-04 Event code=US/EXAC Event type=Examination events Event type=OAO Examiner's Amendment Communication Event publication date=2016-07-08 Event code=US/NOAM Event indicator=Pos Event type=Examination events Event type=OAO Mail Notice of Allowance Event publication date=2016-09-13 Event code=US/APRDY Event indicator=Pos Event type=Examination events Application Is Considered Ready for Issue Event publication date=2016-10-05 Event code=US/ISSM Event indicator=Pos Event type=Examination events Event type=OAO Issue Notification Mailed Event publication date=2016-10-24 Event code=US/PET Event type=APL Petition Entered Event publication date=2016-10-25 Event code=US/B2 Event indicator=Pos Event type=Event indicating In Force Granted patent as second publication Publication country=US Publication number=US09476076 Publication stage Code=B2 Publication date=2016-10-25 Standardized publication number=US9476076 Event publication date=2016-10-27 Event code=US/NOAC Event type=Examination events Event type=OAO Corrected Notice of Allowance Event publication date=2016-11-09 Event code=US/ISSM Event indicator=Pos Event type=Examination events Event type=OAO Issue Notification Mailed Event publication date=2016-11-29 Event code=US/B2 Event indicator=Pos Event type=Event indicating In Force Granted patent as second publication Publication country=US Publication number=US9506094 Publication stage Code=B2 Publication date=2016-11-29 Standardized publication number=US9506094 Event publication date=2016-11-29 Event code=US/ERNG All references to Patent No. 9,476,076 to SEIKO HIRANO of Kanagawa, JP for METHOD FOR PRODUCING L-AMINO ACID USING MICROORGANISM HAVING INCREASED PHOSPHATE TRANSPORTER ACTIVITY appearing in the Official Gazette of October 25, 2016 should be deleted since no patent was granted. Event publication date=2016-11-29 Event code=US/354 Event indicator=Pos Event type=Extension of term of duration of protection Patent term extended under 35 U.S.C 154(b) until/for Delays (A,B,C): 0 Overlap Delays: 0 Non Overlap Delays: 0 PTO Office Delays: 0 Applicant Delays: 0 Adjustment total: Number of days of extension=0
最新评论
暂无评论。