SUBSTITUTED ACIDS [HOMOTETRAM]- AND [HOMOTETRONICOS] FOR [HETARILA], ITS PROCESS FOR PREPARATION, ITS APPLICATIONS AND ITS INTERMEDIATE, COMPOSITION [PRAGUICIDA], [MICROBICIDA] AND HERBICIDE AND ITS PROCESS OF PREPARATION, AND NOT THERAPEUTICAL PROCESS WI 机翻标题: 暂无翻译,请尝试点击翻译按钮。

源语言标题
(BR200116661) Ácidos homotetram- e homotetrônicos substituídos por hetarila, seu processo para preparação, suas aplicações e seus intermediários, composição praguicida, microbicida e herbicida e seu processo de preparação, e processo não terapeutico para
公开号/公开日
BR0116661 A 2003-09-23 [BR200116661] BRPI0116661 A1 2003-09-23 [BRPI0116661] BRPI0116661 A2 2011-08-23 [BR200116661] BRPI0116661 B1 2012-11-13 [BR200116661] / 2003-09-23 2003-09-23 2011-08-23 2012-11-13
申请号/申请日
2001BR-0016661 / 2001-12-21
发明人
FISCHER REINER; ULLMANN ASTRID; TRAUTWEIN AXEL; DREWES MARK WILHELM; ERDELEN CHRISTOPH; DAHMEN PETER; FEUCHT DIETER; PONTZEN ROLF; LOESEL PETER
申请人
BAYER CROPSCIENCE
主分类号
IPC分类号
A01N-043/78;A01N-047/16;C07D-277/20;C07D-277/30;C07D-417/04;C07D-417/06;C07D-417/12;C07D-417/14;C07D-491/052;C07D-491/107
摘要
(BR200116661)
The present invention relates to new hetaryl-substituted homotetramic and homotetronic acids of the formula (I) in which A, B, Q1, Q2, W, G and Het have the meanings stated in the disclosure, to a plurality of processes for their preparation, and to their use as pesticides, microbicides, and herbicides.
 (From US7566731 B2)
机翻摘要
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地址
代理人
代理机构
优先权号
2001DE-1000175 2001-01-04 2001WO-EP15258 2001-12-21
主权利要求
(BR200116661)

1. Compounds, characterized by the fact having the formula (I) wherein
Het represents
W represents oxygen or N -D, X is hydrogen, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 3 -C 6 -alqueniloxi, nitro, cyano or phenyl optionally substituted by halogen, C1 - C6-alkyl, C 1 -C 6 -alkoxy, C 1 -C 4 -halogenoalquila, Ci-C4 haloalkoxy, nitro or cyano, Y represents halogen, C 1 -C 6 -alkyl, Ci-C 6 -halogenoalquila, C 1 -C 6 -alkoxy, C 1 -C 6 haloalkoxy groups, or
V '
V
V 3 V 3 V 1 represents hydrogen, halogen, C 1 -C 12 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkylthio, C 1 -C 6 -alquilsulfinila, C 1 -C 6 -alquilsulfonila, Ci-C 4 -halogenoalquila, C 1 -C 4 haloalkoxy, nitro, cyano or represents phenyl, phenoxy, phenoxy-C 1 -C 4 -alkyl, phenyl-C 1 -C 4 -alkoxy, phenylthio-C1 4 -0-alkyl or phenyl-Ci-C4-alkylthio in each case optionally substituted one or more times by halogen, C1 -C6 -alkyl, C1 -C6 -alkoxy, C 1 -C 4 -halogenoalquila, C 1 - C 4 haloalkoxy, nitro or cyano, V 2 and V 3 represent independent of each other, hydrogen, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, Ci-C 4 -halogenoalquila or C 1 - C 4 haloalkoxy,
V 1 and V 2 together represent in common with the carbon atoms to which they are attached a cycle with 5 or 6 members optionally substituted by C 1 -C 4 -alkyl or halogen, in which optionally one to three carbon atoms may be replaced by oxygen, sulfur or nitrogen,
A represents hydrogen or represents C 1 -C1 2-alkyl, C3-C8-alkenyl, 0 1 -C 6 -alkoxy-C 1 -C 4 -alkyl, C 3 -cicloalquila 8 -0 or C 3 -C 6 -cycloalkyl - C 1 -C 4 -alkyl optionally substituted by halogen, C 1 -C 4 -alkyl or C l - C alkoxy, in which optionally one or two ring members not directly - ing neighbors are replaced by oxygen and / or sulfur or represents phenyl, benzyl, hetaryl having 5 to 6 ring atoms or hetaryl-C 1 -C a -alkyl having 5 to 6 ring atoms in each case optionally substituted by halogen, C 1 -C 6 -alkyl, 0 -halogenoalquila 1 -C 6, C 1 -C 6 -alkoxy, Ci-Cs-haloalkoxy, cyano or nitro, B represents hydrogen or C 1 -C 6 -alkyl, a, B and the carbon atom to which they are attached, represent C 3 -C 10 saturated -cicloalquila or C s -C 10 unsaturated cycloalkyl in which optionally one ring member is replaced by oxygen or sulfur and which are optionally substituted once or twice by C l -CS-alkyl, C -cicloalquila 3 -C 8 -cycloalkyl, C 1 -C 6 -halogenoalquila, C 1 -C 6 -alkoxy, C 1 -CS-alkylthio, halogen or phenyl, D represents hydrogen, represents C l -CS-alkyl, C 3 -C 8 -alquenula, C 3 -C 8 -alquinila, C 1 -C 6 -alkoxy-C 2 -C 6 -alkyl in each case optionally substituted by halogen, represents C 3 -C 8 -cicloalquila or C 3 -C 6 - -Ca cycloalkyl-C l-alkyl optionally substituted by halogen, C 1 -C 4 -alkyl, C 1 -C 4 alkoxy or C 1 -C 4 -halogenoalquila in which optionally one ring member is replaced by oxygen or sulfur, A and Q 1 represent common -alcanodiila C 3 -C 6 optionally substituted by C l -Ca -alkyl or C 1 -C 4 -alkoxy, D and Q 1 represent common C 3 -C 6 -alcanodiila in each case optionally substituted once or twice by identical or different C1 -C4 - alkyl, C 1 -C 4 -alkoxy or
Q 1 represents hydrogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy-C1 -C2 alkyl, C 3 -C 8 -cicloalquila optionally substituted by fluorine, chlorine, C1 -C4 - alkyl, C 1 - -halogenoalquila C 2 or C 1 -C 4 -alkoxy, in which optionally one methylene group is replaced by oxygen or sulfur or represents phenyl optionally substituted by halogen, Ci-C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 2 - halogenoalquila, C 1 -C 20 haloalkoxy, cyano or nitro, or Q 2 represents hydrogen or CrC 4 -alkyl,
Q1 and Q2 represent in common with the carbon atom to which they are attached, C 3 -C 7 -cicloalquila in which optionally one ring member is replaced by oxygen or sulfur, optionally substituted by C 1 -C 6 0-alkyl, C 1 -C 6 -alkoxy or C 1 -C 2 -halogenoalquila, G represents hydrogen (a) or one of the groups 4 DRO 2 -) LR 'it G)) --- - MR (c) just-- R3 (d) // Q., US 5 (e)
R6
--- C / U 1:17
And (f)
OR
(G) in particular (a), (b), (c) or (g) in which E represents a metal ion or an ammonium ion, L represents oxygen or sulfur and M represents oxygen or sulfur, R 1 represents Ci -C 20 -alkyl, C 2 -C 20 -alquenila, -C8 -alkoxy-C 1 -C 8 -alkyl, C 1 -C 8 -alkylthio-C 1 -C 8 -alkyl, poly-C 8 -C -alkoxy-Ci-C 8 -alkyl, in each case optionally substituted by halogen, or represents C 3 -C 8 - cycloalkyl optionally substituted by halogen, Ci-C6-alkyl or C1-C6-alkoxy, in which optionally one or more not directly neighboring ring members are replaced by oxygen and / or sulfur, represents phenyl optionally substituted by halogen, cyano -, nitro, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -halogenoalquila C i -C 6 haloalkoxy, C 1 -C 6 -alkylthio or C 6 -C -alquilsulfonila represents phenyl-C 1 -C 6 -alkyl optionally substituted by halogen, nitro, cyano, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, Ci-C 6 -halogenoalquila or C 1 -C 6 haloalkoxy, represents hetaryl having 5 or 6 members optionally substitutes tuted by halogen, C 1 -C 6 -alkyl or trifluormetila, represents phenoxy-C 1 -C 6 -alkyl optionally substituted by halogen or C 1 -C 6 -alkyl or represents hetariloxi-Ci-C6-alkyl having 5 or 6 members optionally substituted by halogen, amino or C 1 -C 6 -alkyl, R 2 is C 1 -0 20 -alkyl, C 2 -C 20 -alquenila, C1 -C8 -alkoxy-C2 r C alkyl, poly-C 1 -C 8 -alkoxy-C2 -C8 alkyl in each case optionally substituted by halogen, represents C 3 -C 8 -cicloalquila optionally substituted by halogen, C 1 -C 6 -alkyl or C 1 -C 6 -alkoxy or represents phenyl or benzyl in each case optionally substituted by halogen, cyano, nitro, C -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -halogenoalquila or C 1 -C 6 haloalkoxy, R 3 is C i -C 8 -alkyl optionally substituted by halogen or represents phenyl or benzyl in tuted each case optionally substitutes by halogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 4 -halogenoalquila, C1 -C4 haloalkoxy, cyano or nitro, R 4 and R 5 represent independent one another, Ci-C 8 -alkyl, C 1 -C 8 -alkoxy, 0 1 -C 8 -alkylamino, di (Ci-C8-alkyl) amino, C 1 -C 8 -alkylthio, C2 C8 -alqueniltio, C 3 -C 7 -cicloalquiltio in each case optionally substituted by halogen or represents phenyl, benzyl, phenoxy or phenylthio each case optionally substituted by halogen, nitro, cyano, C 1 -C 4 -alkoxy, C 1 -C 4 haloalkoxy, C 1 -C 4 -alkylthio, C 1 -C 4 -halogenoalquiltio, Ci-C 4 -alkyl or C 1 -C 4 -halogenoalquila, R 6 and R 7 independently of one another represent hydrogen, represent C 1 -C 8 -alkyl C r C r cycloalkyl, C 1 -C 8 -alkoxy, C 3 -C 8 -alquenila, C 1 -C 8 -alkoxy-C 1 -C 8 -alkyl in each case optionally substituted by halogen, represent optionally substituted phenyl by halogen, C1-C8 halogenoalquila, C 1 -C 8 -alkyl or C 1 -C 8 -alkoxy, represent benzyl optionally substituted by halogen, C 1 -C 8 -alkyl, Ci-C 8 or C 1 -C -halogenoalquila 8 -alkoxy or together with the N atom to which they are attached represent a radical C 3 -C 6 -alkylene, optionally substituted by Ci-C4-alkyl in which optionally one carbon atom is replaced by oxygen or sulfur.
2. Compounds of formula (I) according to claim 1, characterized by the fact that:
Y
Het represents C
W represents oxygen or N -D, X is hydrogen, chlorine, bromine, Ci-C4-alkyl or phenyl optionally substituted once to twice by fluorine, chlorine, bromine, C1 0 4 -alkyl, C 1 -C 2 - haloalkoxy, nitro or cyano, Y represents chlorine, bromine, C 1 -C 4 -alkyl, C 1 -C 4 -halogenoalquila, C 1 -C 4 -alkoxy, C 1 -C 4 haloalkoxy groups, or
V '
OR
V 1 represents hydrogen, fluorine, chlorine, bromine, C 1 -C 6 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 2 -halogenoalquila, Ci-C2 haloalkoxy, nitro, cyano or represents phenyl, phenoxy, phenoxy-C l -C 2 -alkyl, phenyl-C 1 -C 2 -alkoxy, phenylthio-C1-C2-alkyl or phenyl-Ci-C2-alkylthio in each case optionally substituted once or twice by fluorine, chlorine, bromo, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C1 -C2 halogenoalquila, C 1 -C 2 haloalkoxy, nitro or cyano, V 2 represents hydrogen, fluorine, chlorine, bromine, C 1 - C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 2 -halogenoalquila or Ci-C2 haloalkoxy, V 1 and V 2 together represent in common with the carbon atoms to which they are attached a cycle with 5 or 6 membered optionally substituted by fluorine or methyl, wherein optionally one Qu two carbon atoms may be replaced by oxygen, a represents hydrogen, represents Ci-C8-alkyl, Ci-C4-alkoxy-
C 1 -C 2 -alkyl in each case optionally substituted by fluorine, represents C 5 -C 6 -cicloalquila or C 3 -C 6 -cycloalkyl-Ci-C2-alkyl optionally substituted by from fluorine, chlorine, methyl, ethyl or methoxy, in which optionally one ring member is replaced by oxygen or sulfur or represents phenyl or benzyl in each case optionally substituted by fluorine, chlorine, bromine, C 1 - C 4 -alkyl, C 1 -C 2 -halogenoalquila C 1 -C 4 -alkoxy or Ci-C2 haloalkoxy, B represents hydrogen or C 1 -C 4 -alkyl, a, B and the carbon atom to which they are attached represent saturated C 5 -C 7 -cicloalquila in which optionally one ring member is replaced by oxygen and which is optionally substituted once by C 1 -C 4 -alkyl, trifluormetila or C 1 -C 4 -alkoxy, D represents hydrogen, represents C 1 -C 6 -alkyl C 3 -C 6 -alquenila, C 1 -C 4 -alkoxy-C 2 -C 3 -alkyl in each case optionally substituted by fluorine, represents C 3 -C 7 -cicloalquila or C 3 -C 6 -cycloalkyl-C -C 2 -alkyl optionally substituted by C 1 -C 2 -alkyl, fluorine or chlorine, in which optionally one methylene group is replaced by oxygen, a and Q 1 together represent C 3 -C 4 -alcanodiila, D and Q 1 together represent 0 -C 3 -alcanodiila 4, Q 1 is hydrogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy-C 1 -C 2 -alkyl or represent C 3 -C 6 optionally substituted by -cicloalquila methyl or methoxy, in which optionally one methylene group is replaced by oxygen, Q 2 represents hydrogen, methyl or ethyl,
Q 1 and Q 2 represent together with the carbon to which they are attached, C 5 -C 6 saturated -cicloalquila, optionally substituted by C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy, in which possibly a member of ring is replaced by oxygen, G represents particularly preferably hydrogen (a) or one of the groups R 1 2 3 4 DRO (b) R (c) SOF RP
(D) // R 6
(and),
And (f) or N to '(g) L
in particular (a), (b), (c) or (g) in which
E represents a metal ion or an ammonium ion, L represents oxygen or sulfur and M represents oxygen or sulfur, R 1 represents C 1 -C 16 -alkyl, C 2 -C 16 -alquenila, C 1 -0 4 -alquiltio- C 1 -C 2 -alkyl in each case optionally substituted by fluorine or chlorine, or represents C 3 -C 7 -cicloalquila optionally substituted by fluorine, chlorine, C 1 -C 6 -alkyl or C 1 -0 5 -alkoxy, in which optionally one or two ring members not directly neighbors are replaced by oxygen and / or sulfur, represents phenyl optionally substituted by fluorine, chlorine, bromine, cyano, nitro, C l -Ca -alkyl, C 1 -C 4 -alkoxy, trifluormetila or trifluoromethoxy, represents pyridyl or thienyl optionally substituted in each case 1 5 tuted by fluorine, chlorine, bromine, methyl, ethyl or trifluormetila, R 2 is C 1 -C 16 -alkyl, C 2 -C 1 -C 6 or C -alquenila C 1 -C 4 -alkoxy-C 2 -alkyl in each case optionally substituted by fluorine, represents C 3 -C 7 -cicloalquila optionally substituted by I - IIIa, ethyl or methoxy or represents phenyl or benzyl in each case optionally substituted by fluorine, chlorine, bromine, cyano, nitro, C l -Ca -alkyl, C 1 -C 3 -alkoxy, trifluormetila or trifluoromethoxy, R 3 represents C 6 -C -alkyl optionally substituted by fluorine or represents phenyl optionally substituted by fluorine, chlorine, bromine, C1-Ca-alkyl, C1-C4-alkoxy, trifluormetila, trifluoromethoxy, cyano or nitro, R 4 represents C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, Ci-C 6 -alkylamino, di- (C 1 -C 6 alkyl) amino, Ci-C 6 -alkylthio or represents phenyl, benzyl, phenoxy or phenylthio each case optionally substituted by fluorine, chlorine, bromine, nitro, cyano, C 1 -C 3 -alkoxy, trifluoromethoxy, C 1 -C 3 -alkyl or trifluormetila, R 5 represents C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy or C 1 - C -alkylthio, R 6 represents hydrogen, C 1 -C 6 -alkyl, C 3 -C 6 -cicloalquila, C 1 -C 6 -alkoxy, C 3 -C 6 -alquenila, Ci-C 6 -alkoxy-CI- C6-alkyl, represents phenyl optionally substituted by fluorine, chlorine, bromine, trifluormetila, Ci-C 4 -alkyl or C 1 -C 4 -alkoxy, represents benzyl optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, or trifluormetila methoxy, R7 is hydrogen, Ci-C 6 -alkyl or C 3 -C 6 -alquenila, R 6 and R 7 together with the N atom to which they are attached, a radical C 4 -C 6 -alkylene optionally substituted by methyl or ethyl, in which optionally one methylene group is replaced by oxygen or sulfur.
3. Compounds of formula (I) according to claim 1, characterized by the fact that:
.--. 5 - Y
Het represents C
W represents oxygen or N -D, X is chlorine, bromine, methyl, ethyl, n -propila, isopropyl, isobutyl or nbutila, Y represents methyl, ethyl, n -propila i -propila, n-butyl, i-butyl, tert-butyl or the group
V 1 represents hydrogen, fluorine, chlorine, bromine, methyl, ethyl, n - propyl, isopropyl, n-butyl, isobutyl, tert-butyl, methoxy, ethoxy, n-propoxy, isopropoxy, trifluormetila, trifluoromethoxy, V 2 represents hydrogen fluoro, chloro, methyl, ethyl, n -propila, isopropyl, methoxy, ethoxy, trifluormetila or trifluoromethoxy, A represents hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, metoximetila, etoximetila, B represents hydrogen, methyl or ethyl a, B and the carbon atom to which they are attached represent saturated C 5 -C 6 -cicloalquila in which optionally one ring member is replaced by oxygen and which is optionally substituted once with methyl, ethyl, n -propila, isopropyl, butyl, trifluormetila, methoxy, ethoxy, n-propoxy or n-butoxy,
D represents hydrogen, methyl, ethyl, propyl, isopropyl, allyl, 2-butenyl, metoxietila, etoxietila, cyclopropyl, cyclopentyl or cyclohexyl, A and Q 1 together represent C 3 -C 4 -alcanodiila, D and Q 'together represent C 3 -alcanodiila -C 4, Q 1 represents hydrogen, methyl, ethyl, propyl, isopropyl, cyclo - propyl, cyclopentyl or cyclohexyl, Q 2 represents hydrogen, methyl or ethyl, Q, ie, Q 2 represent together with the carbon atom to which are attached, C 5 -C 6 -cicloalquila optionally substituted by methyl, ethyl, propyl, isopropyl, methoxy, ethoxy, propoxy or butoxy, in which optionally one ring member is replaced by oxygen, G represents hydrogen (a) or of OLR 4 groups R 1 (b),, R 2 (c), SO 3 R (d)
- P., // R (e)
R6
And (f) OR
N 1: t7 (g) L
in particular (a), (b), (c) or (g) in which
E represents a metal ion or an ammonium ion, L represents oxygen or sulfur and M represents oxygen or sulfur, R 1 represents C 1 -C 14 -alkyl, C 2 -C 14 -alquenila, C1 -C4 -alkoxy-C1 C 2 -alkyl, C 1 -C 4 -alkylthio-C 1 -C 2 -alkyl in each case optionally substituted by fluorine or chlorine, or represents C 3 -C 6 -cicloalquila optionally substituted by fluorine, chlorine, methyl, ethyl or methoxy in which optionally one or two ring members not directly neighbors are replaced by oxygen and / or sulfur, represents phenyl optionally substituted by fluorine, chlorine, bromine, cyano, nitro, methyl, ethyl, isopropyl, tert-butyl, methoxy, trifluormetila or trifluoromethoxy, represents thienyl or pyridyl in each case optionally substituted by fluorine, chlorine, bromine or methyl, R 2 is C 1 -C 14 -alkyl, C 2 -C 14 -alquenila or C 1 -C 4 -alkoxy C 2 -C 3 -alkyl in each case optionally substituted by fluorine, represents C 3 -C 6 -cicloalquila optionally substituted by methyl, ethyl or methoxy, or represents phenyl or benzyl in each case optionally substituted by fluorine, chlorine, cyano, nitro, methyl, ethyl, isopropyl, tert-butyl, methoxy, trifluormetila or trifluoromethoxy, R 3 represents methyl, ethyl, n -propila, isopropyl optionally substituted by fluorine or represents phenyl optionally substituted by fluorine, chlorine, bromine, methyl, tert-butyl, methoxy, trifluormetila, trifluoromethoxy, cyano or nitro,
R4 represents Ci-C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -alkylamino, di- (C 1 -C 4 alkyl) amino, C 1 -C 4 -alkylthio or represents phenyl, phenoxy or phenylthio each case optionally substituted by fluorine, chlorine, bromine, nitro, cyano, C 1 - C 2 -alkoxy, trifluoromethoxy or C 1 -C 3 -alkyl, R 5 represents methyl, ethyl, methoxy, ethoxy, methylthio or ethylthio, R 6 and R 7 represent independently of one another hydrogen, represent C 1 -C 4 -alkyl, C 3 -C 6 -cicloalquila, C 1 -C 4 -alkoxy, C 3 -C 4 -alquenila R 7 is hydrogen, C 1 -C 4 -alkyl or C 3 -C 4 -alquenila, R 6 and R 7 together with the N atom to which they are attached, a radical C 5 -C 6 -alkylene, in which possibly a group methylene is replaced by oxygen or sulfur.
4. Compounds of formula (1) according to claim 1, characterized by the fact that:
Het represents W represents oxygen or N -D, X represents chlorine, methyl, ethyl, isopropyl or n -propila,
Y is
Cl
Cl
CF3
C 2 H 5 0
Cl
Cl
OR
A represents hydrogen or methyl, B represents hydrogen or methyl, A, B and the carbon atom to which they are attached represent C 6 -cicloalquila in which optionally one ring member is replaced by oxygen.

D represents hydrogen or cyclopropyl, D and Q 1 together represent C 3 -C 4 -alcanodiila, Q 1 represents hydrogen or methyl, Q 2 represents hydrogen or methyl, Q 1 and Q 2 together with the carbon atom to which they are attached represent C 6 -cicloalquila in which optionally one ring member is replaced by oxygen, G represents hydrogen (a) or one of the groups
O
R i
OR 6 vile "R 2 (c) OR
R7 N (g)
(B) in which
M represents oxygen or sulfur, R 1 is C 4 -C 14 -alkyl, represents phenyl or pyridyl optionally substituted by chloro, R 2 is C 1 -C 4 -alkyl, phenyl or benzyl, R 6 and R 7 together with the atom N to which they are attached represent a radical C 5 -C 6 -alkylene, in which optionally one methylene group is replaced by oxygen.
5. Process for the preparation of compounds of formula (I) as defined in claim 1, characterized by the fact that to obtain (A) replaced tetrahydropyridin-2,4-diones or their enols of the formula (I-1-a) Q 2 0 1 D
Ni
THE
13
HO
In which Het
A, B, D, Q 1, Q 2 and Het have the meanings indicated above are condensed intramolecularly N-acilaminoacido esters of formula (II)
B \\,. 0O 2 R 8 IQ> \\ Q 2 N
In which Het
A, B, D, Q 1, Q 2 and Het have the meanings indicated above and R8 represents alkyl, in the presence of a diluent and in the presence of a condensed intramolecularly base, (B) substituted 5,6-dihydropyrones of formula ( I-2-a) Q 2 Q i
O
Het
(I-2-a)
HO
wherein A, B, Q 1, Q 2 and Het have the meanings indicated above, 0-acyl-hydroxycarboxylic acid esters of the formula (III)
In which Het
A, B, Q 1, Q 2 and Het have the meanings indicated above
R 8 represents alkyl, in the presence of a diluent and in the presence of a condensed intramolecularly base, (C) compounds of formulas (I-1-b) to (I-2-b) shown above in which A, B, Q 1, Q2, KW and Het have the meanings indicated above, compounds of formulas (I-1-a) to (I-2-a) shown above in which a, B, Q 1, Q 2, W and Het have the meanings given above in each case (C) are reacted with acid halides of the formula (IV) R 1 Hal
in which
R 1 has the meaning indicated above and Hal represents halogen or (V) in which R 1 has the meaning given above, optionally in the presence of a diluent and optionally in the presence of an acid binding agent; 

(D) compounds of formulas (I-1-c) to (I-2-c) shown above in which A, B, Q1, Q2, M, W and Het have the meanings indicated above and
(3) are reacted with carboxylic acid anhydrides of the formula
R 1 -R 1 -CO -00 -0 (V)
L represents oxygen, compounds of formulas (I-1-a) to (I-2-a) shown above in which A, B, Q 1, Q 2, W and Het have the meanings indicated above, are in each case reacted with chloroformic acid esters or chloroformic acid thioesters of the formula (VI) R 2 -M-CO-Cl (VI) in which
R 2 and M have the meanings given above, optionally in the presence of a diluent and optionally in the presence of an acid binding agent; 

(E) compounds of formulas (I-1-c) to (I-2-c) shown above in which A, B, Q 1, Q 2, R 2, M, W and Het have the meanings indicated above and L represents sulfur, compounds of formulas (I-1-a) to (I-2-a) shown above in which a, B, Q 1, Q 2, W and Het have the meanings indicated above, are in each case cloromonotioformico reacted with acid esters or cloroditioformico acid esters of formula (VII) Cl (M 2 -R (VII) wherein
M and R 2 have the meanings given above, optionally in the presence of a diluent and optionally in the presence of an acid binding agent
(F) compounds of the formulas (I-1-d) to (I-2-d) shown above in which A, B, Q 1, Q 2, R 3, W and Het have the meanings indicated above, compounds of formulas (I-1-a) to (I-2-a) shown above in which a, B, Q 1, Q 2, W and Het have the meanings given above in each case are reacted with sulphonic acid chlorides of formula (VIII) R 3 -s0 2 -Cl (VIII) in which R 3 has the meaning given above, optionally in the presence of a diluent and optionally in the presence of an acid binding agent; 

(G) compounds of the formulas (1-1-e) to (I-2-e) shown above, Q 2, r -. K 4, in which A, B, L, Q 1, R 5, W and Het have the meanings indicated above, compounds of formulas (I-1-a) to (I-2-a) shown above in which A, B, Q 1, Q 2, W and Het have the meanings indicated above, are in each case reacted with phosphorus compounds of the formula (IX) R 4 Hal-P.,. R5 (IX) in which
L, R 4 and R 5 have the meanings indicated above and Hal represents halogen, if appropriate in the presence of a diluent and if appropriate in the presence of an agent fastener acid, (H) compounds of formulas (1-1-0 through (1- 2-0 shown above in which a, B, E, Q 1, Q 2, W and Het have the meanings indicated above, compounds of formulas (I-1-a) to (I-2-a) shown above, in which a, B, Q 1, Q 2, W and Het have the meanings indicated above, are in each case reacted with metal compounds or amines of the formulas (X) or (XI) Me (OR11) t (X)
R13. R11,, R12 (XI) in which Me represents a mono- or divalent metal, t represents the number 1 or 2 and
R 11, R 12,.- 13 K independent of each other, represent hydrogen or alkyl optionally in the presence of a diluent, (I) compounds of the formulas (I-1-g) to (I-2-g) shown above in which a, B, L, Q 1, Q 2, R 6, R 7, W and Het have the meanings indicated above, compounds of the formula (1-1-a) to (I-2-a) shown above in which
A, B, Q 1, Q 2, W and Het have the meanings given above in each case (a) are reacted with isocyanates or isothiocyanates of the formula R 6 -N = C = L (XII), R 6 and L have the meanings indicated above, optionally in the presence of a diluent and if appropriate in the presence of a catalyst or (13) are reacted with carbamic acid chlorides or thiocarbamic acid chlorides of formula (XIII)
(XII) wherein
(XIII)
Cl
FR 7 'in which L, R 6 and R 7 have the meanings given above, optionally in the presence of a diluent and optionally in the presence of an acid binding agent.
6. Compound, characterized in that it has the formula
ASS)
Het in which A, B, D, Q 1, Q 2, Het and R 8 have the meanings indicated above.
7. Compound, characterized in that it has the formula
(XVI)
(XVI)
Het in which A, B, D, Q 1, Q 2 and Het have the meanings indicated above.
8. Compound, characterized in that it has the formula
(XX)
Het
(XX) in which A, B, D, Q 1, Q 2 and Het have the meanings indicated above.
9. Compound, characterized in that it has the formula
Het in which A, B, Q 1, Q 2, Het and R 8 have the meanings indicated above.
10. Composition pesticides, microbicides and herbicides, characterized by the fact that it contains an amount of at least one compound of formula (I) as defined in claim 1.
11. Non-therapeutic method of combating animal pests, unwanted growth of plants and fungi in plants or part of plants, characterized by the fact that it makes acting compounds of formula (I) as defined in claim 1 on pests and / or their habitat.
12. Non-therapeutic application of compounds of formula (I) as defined in claim 1, characterized by the fact that they are for combating animal pests, unwanted growth of plants and fungi in plants or parts of plants.
13. Process for preparing compositions of pesticides, microbicides and herbicides, characterized in that mixing compounds of formula (I) as defined in claim 1 with extenders and / or surface-active substances.
14. Application of compounds of formula (I) as defined in claim 1, characterized by the fact that it is for preparing com - positions pesticides, microbicides and herbicides.

Machine Translated
法律状态
(BR200116661)
LEGAL DETAILS FOR BR0116661

Actual or expected expiration date=2015-12-01   
Legal state=DEAD   
Status=LAPSED 



Event publication date=2001-12-21 
Event code=BR/APP 
Event indicator=Pos 
Event type=Examination events 
Application details

Application country=BR BR0116661 
Application date=2001-12-21 
Standardized application number=2001BR-0016661 



Event publication date=2003-09-23 
Event code=BR/A1 
Event indicator=Pos 
Event type=Examination events 
Published application

Publication country=BR 
Publication number=BRPI0116661 
Publication stage Code=A1 
Publication date=2003-09-23 
Standardized publication number=BRPI0116661 



Event publication date=2003-09-23 
Event code=BR/A 
Event type=Examination events 
Published application

Publication country=BR 
Publication number=BR0116661 
Publication stage Code=A 
Publication date=2003-09-23 
Standardized publication number=BR200116661 



Event publication date=2011-08-23 
Event code=BR/A2 
Event indicator=Pos 
Event type=Examination events 
Application for a patent of invention / pipeline patent published without search report

Publication country=BR 
Publication number=BRPI0116661 
Publication stage Code=A2 
Publication date=2011-08-23 
Standardized publication number=BR200116661 



Event publication date=2011-08-23 
Event code=BR/B07A 
Event type=Examination events 
Technical examination (opinion): publication of technical examination (opinion)
Ciencia de parecer: conhecimento de parecer tecnico



Event publication date=2012-04-17 
Event code=BR/B06F 
Event type=Administrative notifications 
Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
Exigencias tecnicas e formais: exigencia - art. 34 da lpi



Event publication date=2012-07-17 
Event code=BR/B09A 
Event type=Event indicating In Force 
Event type=Administrative notifications 
Decision: granting
Decisao: deferimento



Event publication date=2012-11-13 
Event code=BR/B1 
Event indicator=Pos 
Event type=Event indicating In Force 
Granted patent / Granted pipeline patent

Publication country=BR 
Publication number=BRPI0116661 
Publication stage Code=B1 
Publication date=2012-11-13 
Standardized publication number=BR200116661 



Event publication date=2012-11-13 
Event code=BR/B16A 
Event indicator=Pos 
Event type=Event indicating In Force 
Event type=Administrative notifications 
Patent or certificate of addition of invention granted
Concessao de patente ou certificado de adicao de invencao: concessao de    patente ou certificado de adicao de invencao
PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/11/2012, MEDIANTE O RECOLHIMENTO DA TAXA QUINQUENAL DE MANUTENCAO (ARTIGOS 119 E 120 DA LPI) E OBSERVADAS AS DEMAIS CONDICOES LEGAIS. 



Event publication date=2015-12-01 
Event code=BR/B21F 
Event indicator=Neg 
Event type=Event indicating Not In Force 
Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
Extincao de patente e certificado de adicao de invencao: extincao - art. 78 inciso iv da lpi
REFERENTE A 14A ANUIDADE. 



Event publication date=2016-03-29 
Event code=BR/B24J 
Event indicator=Neg 
Event type=Event indicating Not In Force 
Lapse because of non-payment of annual fees (definitively: art 78 iv lpi  resolution 113/2013 art. 12)
Manutencao da extincao - art. 78 inciso iv da lpi - artigo 12, da resolucao 113/2013
EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.
专利类型码
A A1 A2 B1
国别省市代码
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