The testing of vented explosion of methane-air mixtures was conducted in a custom-designed 4.5-m 3 steel chamber. Methane concentrations in the mixed gas varied between 7 and 13 vol% and the static hysteresis time was set as 0, 1, and 5 min to characterize strong, medium and weak turbulence levels. The effects of concentration and initial turbulence on pressure characteristics and flame development were investigated. It is found that the quasi-static pressure in the chamber during vented explosion can be divided into three stages: pressure release, Helmholtz oscillation, and acoustic oscillation. The Helmholtz oscillation at a frequency of about 20–40 Hz is produced after the peak pressure P 1 caused by the pressure release at all concentrations; however, the acoustic oscillation at a frequency of about 300 Hz only occurs after Helmholtz oscillation when the concentration is near the optimum. In the early stage of internal flame development, the cellular structure is generated due to hydrodynamic instability and diffusive-thermal instability, and the flame front is distorted owing to the instability caused by venting. Initial turbulence distorts the flame front, significantly increases the peak pressure, and stimulates the generation of acoustic oscillation at the upper and lower limits of concentration. Under the influence of initial high turbulence, the internal flame propagation distance has a power function relationship with time, and the turbulence acceleration factor and distance also show a power function relationship.