Immunogenic glycopeptide compounds, pharmaceutical compositions and uses thereof 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
WO2017048823 A1 2017-03-23 [WO201748823] / 2017-03-23
申请号/申请日
2016WO-US51702 / 2016-09-14
发明人
CHANG CHIH-LONG;WU CHAO-CHIH;
申请人
DCB;MACKAY MEMORIAL HOSPITAL OF TAIWAN PRESBYTERIAN CHURCH & MACKAY MEMORIAL SOCIAL WORK FOUND;
主分类号
IPC分类号
A61K-009/62A61K-038/03C07K-014/705
摘要
(WO201748823) Disclosed herein are immunogenic glycopeptide compounds for inducing immune responses to prevent and/or treat cancer.  Other aspects of the present disclosure are pharmaceutical compositions comprising the immunogenic glycopeptide compounds, and methods using the compounds for preventing and/or treating a cancer in a subject.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2015US-62220923 2015-09-18
主权利要求
(WO201748823) 1. An immunogenic glycopeptide compound, wherein the compound has structural formula (I): (I) wherein P is a carbohydrate antigen selected from Globo H, SSEA4, GD2, GD3, GM2, fucosyl GM1, lewis y Le(y), sialyl-Le(x), sialyl-Le(a), TF, Tn and sialyl-Tn; m = 1 to 4; Y is a pan-DR epitope comprising an amino acid sequence at least 80% identical to AKXVAAWTLKAAA (SEQ ID NO: 1), wherein X is an amino acid residue selected from cyclohexylalanine, phenylalanine, and tyrosine; and n = 1 to 5.
法律状态
(WO201748823) LEGAL DETAILS FOR WO2017048823  Actual or expected expiration date=2019-03-18    Legal state=ALIVE    Status=PENDING     Event publication date=2016-09-14  Event code=WO/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=WO WOUS2016051702  Application date=2016-09-14  Standardized application number=2016WO-US51702     Event publication date=2017-03-23  Event code=WO/A1  Event type=Examination events  Published application with search report  Publication country=WO  Publication number=WO2017048823  Publication stage Code=A1  Publication date=2017-03-23  Standardized publication number=WO201748823  LEGAL DETAILS FOR DESIGNATED STATE EP  Actual or expected expiration date=2035-09-18    Legal state=ALIVE    Status=PENDING   Corresponding cc:  Designated or member state=EP Corresponding appl: EP16847220    Event publication date=2017-05-10  Event code=WO/121  Event type=Designated states  EP: The EPO has been informed by wipo that ep was designated in this application Corresponding cc:  Designated or member state=EP
专利类型码
A1
国别省市代码
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