公开号/公开日

US5441934 A 1995-08-15 [US5441934] / 1995-08-15

申请号/申请日

1993US-08171383 / 1993-12-20

发明人

KRAPCHO KAREN J;JACKSON JOHN R H;JOHNSON JANICE H;DELMAR ERIC G;KRAL JR ROBERT M;

申请人

FMC CORPORATION;NPS PHARMACEUTICALS;

主分类号

IPC分类号

A01H-005/00A01N-037/20A01N-037/44A01N-037/46A01N-063/00A01N-063/02C07K-001/20C07K-014/00C07K-014/435C07K-016/00C07K-016/18C12N-001/21C12N-005/10C12N-015/09C12N-015/82C12P-021/02C12R-001/19

摘要

(US5441934) This invention provides a family of insecticidally effective peptides which may be isolated from Tegenaria spider venom, DNA encoding such insecticidally effective peptides and methods for controlling invertebrate pests.

机翻摘要

暂无翻译结果，您可以尝试点击头部的翻译按钮。

地址

代理人

代理机构

;

优先权号

1992US-07826925 1992-01-24 1993US-08171383 1993-12-20

主权利要求

(US5441934) What is claimed: 19.  A method of controlling invertebrate pests comprising contacting said pests with an insecticidally effective amount of an insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:3. 1. A substantially purified insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:3 and agriculturally or horticulturally acceptable salts thereof. 2. The insecticidally effective peptide of claim 1 wherein the peptide is derived from a spider of the genus Tegenaria. 3. The insecticidally effective peptide of claim 2 wherein the species of spider is Tegenaria agrestis. 4. The peptide of claim 1 further comprising a signal sequence comprising sequence defined in SEQ ID NO:6. 5. The peptide of claim 4 comprising sequence defined in SEQ ID NO:4. 6. A substantially purified insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:9 and agriculturally or horticulturally acceptable salts thereof. 7. The insecticidally effective peptide of claim 6 wherein the peptide is derived from a spider of the genus Tegenaria. 8. The insecticidally effective peptide of claim 7 wherein the species of spider is Tegenaria agrestis. 9. The peptide of claim 6 further comprising a signal sequence comprising sequence defined in SEQ ID NO:6. 10. The peptide of claim 9 comprising sequence defined in SEQ ID NO:10. 11. A substantially purified insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:14 and agriculturally or horticulturally acceptable salts thereof. 12. The insecticidally effective peptide of claim 11 wherein the peptide is derived from a spider of the genus Tegenaria. 13. The insecticidally effective peptide of claim 12 wherein the species of spider is Tegenaria agrestis. 14. The peptide of claim 11 further comprising a signal sequence comprising sequence defined in SEQ ID NO:6. 15. The peptide of claim 14 comprising sequence defined in SEQ ID NO:13. 16. The recombinantly produced peptide comprising SEQ ID NO:3 produced by the method comprising: a) culturing recombinant host cells wherein a recombinant expression vector transformed or transfected or otherwise applied in said host cells has a DNA sequence encoding said peptide, wherein the vector is capable of effecting the expression of said coding sequence in transformed cells;  and b) recovering said insecticidally effective peptide from the recombinant host cell culture or host organism. 17. The recombinantly produced peptide comprising SEQ ID NO:9 produced by the method comprising: a) culturing recombinant host cells wherein a recombinant expression vector transformed or transfected or otherwise applied in said host cells has a DNA sequence encoding said peptide, wherein the vector is capable of effecting the expression of said coding sequence in transformed cells;  and b) recovering said insecticidally effective peptide from the recombinant host cell culture or host organism. 18. The recombinantly produced peptide comprising SEQ ID NO:14 produced by the method comprising: a) culturing recombinant host cells wherein a recombinant expression vector transformed or transfected or otherwise applied in said host cells has a DNA sequence encoding said peptide, wherein the vector is capable of effecting the expression of said coding sequence in transformed cells;  and b) recovering said insecticidally effective peptide from the recombinant host cell culture or host organism. 20. A method of controlling invertebrate pests comprising contacting said pests with an insecticidally effective amount of an insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:9. 21. A method of controlling invertebrate pests comprising contacting said pests with an insecticidally effective amount of an insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:14. 22. An insecticidal composition comprising an insecticidally effective amount of an insecticidally effective comprising amino acid sequence defined in SEQ ID NO:3 and agriculturally or horticulturally acceptable salts thereof in an agriculturally or horticulturally acceptable carrier therefor. 23. An insecticidal composition comprising an insecticidally effective amount of an insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:9 and agriculturally or horticulturally acceptable salts thereof in an agriculturally or horticulturally acceptable carrier therefor. 24. An insecticidal composition comprising an insecticidally effective amount of an insecticidally effective peptide comprising amino acid sequence defined in SEQ ID NO:14 and agriculturally or horticulturally acceptable salts thereof in an agriculturally or horticulturally acceptable carrier therefor. 25. The peptide of claim 1 conjugated to a label or carrier. 26. The peptide of claim 6 conjugated to a label or carrier. 27. The peptide of claim 11 conjugated to a label or carrier.

法律状态

(US5441934) LEGAL DETAILS FOR US5441934  Actual or expected expiration date=2018-01-26    Legal state=DEAD    Status=LAPSED     Event publication date=1993-12-20  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US08171383  Application date=1993-12-20  Standardized application number=1993US-08171383     Event publication date=1993-12-20  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: MCELWAIN, ELIZABETH F    Event publication date=1993-12-20  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1803     Event publication date=1993-12-20  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: FMC0065    Event publication date=1993-12-20  Event code=US/SMALL  Event type=Administrative notifications  Appl Has Filed a Verified Statement of Micro to Small Entity Status Business Entity Status: SMALL    Event publication date=1993-12-20  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=1994-02-25  Event code=US/INCD  Event type=Examination events  Event type=OAO  Notice Mailed--Application Incomplete--Filing Date Assigned    Event publication date=1994-03-30  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: NPS PHARMACEUTICALS, INC., UTAH  Effective date of the event=1994-01-13  ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:KRAPCHO, KAREN J. JACKSON, JOHN R.H. JOHNSON, JANICE H. AND OTHERS REEL/FRAME:006906/0364     Event publication date=1994-03-30  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment Owner: FMC CORPORATION, PENNSYLVANIA  Effective date of the event=1994-01-13  ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:KRAPCHO, KAREN J. JACKSON, JOHN R.H. JOHNSON, JANICE H. AND OTHERS REEL/FRAME:006906/0364     Event publication date=1994-03-30  Event code=US/POAC  Event type=Change of name or address  Change in Power of Attorney (May Include Associate POA)    Event publication date=1994-05-04  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=1994-05-11  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=1994-06-20  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=1994-06-20  Event code=US/RESTREQ  Event type=Examination events  Event type=Corrections  Event type=OAO  Restriction/Election Requirement    Event publication date=1994-07-11  Event code=US/ELC  Event type=Examination events  Event type=OAI  Response to Election / Restriction Filed    Event publication date=1994-08-08  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=1994-10-07  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=1994-11-10  Event code=US/CTNFR  Event type=Examination events  Event type=OAI  Response after Non-Final Action    Event publication date=1994-11-10  Event code=US/POAC  Event type=Change of name or address  Change in Power of Attorney (May Include Associate POA)    Event publication date=1995-02-23  Event code=US/NOAM  Event indicator=Pos  Event type=Examination events  Event type=OAO  Mail Notice of Allowance    Event publication date=1995-07-10  Event code=US/ISSM  Event indicator=Pos  Event type=Examination events  Event type=OAO  Event type=Restitution or restoration  Issue Notification Mailed    Event publication date=1995-08-15  Event code=US/A  Event indicator=Pos  Event type=Event indicating In Force  Patents Granted before 2001-04-15  Publication country=US  Publication number=US5441934  Publication stage Code=A  Publication date=1995-08-15  Standardized publication number=US5441934     Event publication date=1999-03-09  Event code=US/REMI  Event type=Administrative notifications  Maintenance fee reminder mailed    Event publication date=1999-08-16  Event code=US/SULP  Event indicator=Pos  Event type=Restitution or restoration  Event type=Event indicating In Force  Surcharge for late payment    Event publication date=1999-08-16  Event code=US/FPAY  Event indicator=Pos  Event type=Event indicating In Force  Event type=Payment or non-payment notifications  Fee payment recorded   Annual fees payment date=1999-08-16     Year of payment of annual fees=4     Event publication date=1999-10-26  Event code=US/NMFP  Event type=Payment or non-payment notifications  Publication of First Notice of Maintenance Fees Payable. PAYMENT NOTICE YEAR:  Year of payment of annual fees=3     Event publication date=2002-08-27  Event code=US/NMFP  Event type=Payment or non-payment notifications  Publication of First Notice of Maintenance Fees Payable. PAYMENT NOTICE YEAR:  Year of payment of annual fees=7     Event publication date=2003-08-15  Event code=US/FP  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=Payment or non-payment notifications  Expired due to failure to pay maintenance fee  Effective date of the event=2003-08-15     Event publication date=2003-08-15  Event code=US/LAPS  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=Payment or non-payment notifications  Lapse for failure to pay maintenance fees    Event publication date=2003-08-15  Event code=US/EXP  Event indicator=Neg  Event type=Event indicating Not In Force  Patent expired    Event publication date=2006-08-29  Event code=US/NMFP  Event type=Payment or non-payment notifications  Publication of First Notice of Maintenance Fees Payable. PAYMENT NOTICE YEAR:  Year of payment of annual fees=11     Event publication date=2018-01-26  Event code=US/FP  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=Payment or non-payment notifications  Expired due to failure to pay maintenance fee

专利类型码

A

国别省市代码

登录后可以发表评论