Microcapsules 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2002136773 A1 2002-09-26 [US20020136773]US8173159 B2 2012-05-08 [US8173159] / 2002-09-262012-05-08
申请号/申请日
2001US-09873418 / 2001-06-05
发明人
SCHER HERBERT BENSON;CHEN JINLING;MAZEAUD ISABELLE;KANNE DAVID BRAUN;SHIRLEY IAN MALCOLM;WADE PHILIP;PADGET JOHN CHRISTOPHER;WALLER ANNE;
申请人
SYNGENTA;
主分类号
IPC分类号
A01N-025/00A01N-025/28A01N-037/20A01N-037/26A01N-053/00A01N-053/06A01N-053/08A61K-009/16A61K-009/48A61K-009/50B01J-013/14B01J-013/16B01J-013/18C09D-011/00
摘要
(US8173159) A novel microcapsule comprising an encapsulated material which is enclosed within a solid permeable shell of a polymer resin having surface modifying compounds capable of reacting with isocyanate incorporated therein is disclosed.  The process for producing such microcapsules is likewise disclosed.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2000US-60209719 2000-06-05 2000US-60209734 2000-06-05 2001US-09873418 2001-06-05
主权利要求
(US8173159) What is claimed is: 1.  A microcapsule comprising an encapsulated liquid enclosed within a solid permeable shell of a polymer resin wherein said polymer resin is made by the polymerisation of a urea formaldehyde prepolymer, in which the methylol ( -- CH2OH) groups have optionally been partially etherified by reaction with a C4-C10 alkanol, and the polymer resin has incorporated therein at least one surface modifying compound having a moiety  -- X as defined below which reacts with the methylol or etherified methylol moieties in the urea formaldehyde prepolymer;   and wherein said surface modifying compound is of formula (IA), (IB), (IC), (ID), (IIA), (IIB), (IIC), (IIIA), (IIIB), (IIIC), (IIID) or (IVA) or is a sulfonate polyester polyol    X -- Y1 -- Z  (IA)       R4 -- O(PO)r(EO)s -- X  (IB)       R4' -- (PO)r'(EO)s'(PO)t -- -X  (IC)       X-(EO)a(PO)b -- X'  (IIA)       X -- (PO)a'(EO)b'(PO)c -- X'  (IIB)       X -- Y2 -- C(Z)(R6) -- Y2' -- X'  (IIIA)       X -- Y -- NH -- Y' -- Z  (IVA)    wherein the sulfonate polyester polyol is prepared by reacting sodium sulphoisophthalic acid, adipic acid, cyclohexane dimethanol, methoxy-polyethylene glycol (MW 750) and trimethylol propane to give a product having a hydroxyl number in the range of from 150 to 170;   and wherein in formulae (IA), (IB), (IC), (IIA), (IIB), (IIC), (IIIA), (IIIB), (IIIC), (IIID) and (IVA) above; Z if present is sulphonate, carboxylate, phosphonate, phosphate, quaternary ammonium, betaine, oxyethylene or an oxyethylene-containing polymer;   and wherein in formulae (ID) above Z is sulphonate, phosphonate, phosphate, quaternary ammonium, betaine, oxyethylene or an oxyethylene-containing polymer;   and each X or X' is, independently, hydroxyl, thiol, a group  -- NHA wherein A is hydrogen or C1 to C4 alkyl, or a group  -- CO -- OR where R is hydrogen or a hydrocarbyl moiety having 1-30 carbon atoms optionally linked or substituted by one or more halo, amino, ether or thioether groups or combinations of these;   and wherein in formula (IA) Y1 is a moiety linking X and Z and is a straight or branched alkyl chain containing from 1 to 20 carbon atoms or is naphthyl, cyclopentyl or cyclohexyl;   and wherein in formula (IB) R4 is an end-capping group which is C1 to C4 alkyl, r and s are independently from 0 to 3000, provided that s is not 0 and the total of r+s is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively which may be arranged in random or block formation;   and wherein in formula (IC) R4' is an end-capping group which is C1 to C4 alkyl, r', s' and t are, independently, from 0 to 2000, provided that s' is not 0 and the total of r'+s'+t is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively;   and wherein formula (ID) X and Z are as defined above; or X and Z are adjacent substituents which together with the carbon atom to which they are bound form a cyclic anhydride capable of ring-opening;   and wherein in formula (IIA) a and b are independently from 0 to 3000, provided that a is not 0 and the total of a+b is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively which may be arranged in random or block formation;   and wherein in formula (IIB) a', b' and c are, independently, from 0 to 2000, provided that b' is not 0 and the total of a'+b'+c is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively;   and wherein in formula (IIC) R14 and R15, which may be the same or different, are hydrogen, C1 to C20 straight or branched chain alkyl, aryl or C1 to C4 aralkyl, wherein each aryl group may be optionally substituted by C1 to C4 alkyl, nitro or halo, and Y4 and Y4' which may be the same or different are     -- R8 --  or  -- R7-(L1)n-    wherein R7 and R8 are, independently, C1 to C10 straight or branched chain alkyl linking groups optionally substituted by halogen or C1 to C4 alkoxy and (L1)n is a polyoxyalkyene group wherein n is from 2 to 20 and A- is a suitable anion;   and wherein in formula (IIIA) R6 is hydrogen or a C1 to C4 alkyl group optionally substituted by ether or halogen and Y2 and Y2', which may be same or different, are independently     -- R7-(L1)n- or  -- R8     wherein R7 and R8 are, independently, C1 to C10 straight or branched chain alkyl linking groups optionally substituted by halogen or C1 to C4 alkoxy and (L1)n is polyoxyethylene, polyoxypropylene or polyoxybutylene where n is from 2 to 20;   and wherein in formula (IIIB) X and Z are as previously defined;   and wherein in formula (IIIC) Y3, Y3' and Y3'' individually represent a direct link between X or Z (as the case may be) and the ring structure or may be a group    -(L2)-R9 --     where L2 is an ester linking group  -- C(O) -- O --  and R9 is oxyethylene, oxypropylene or oxybutylene or polyoxyethylene, polyoxypropylene or polyoxybutylene having a degree of polymerisation from 2 to 20;   and wherein in formula (IIID) R10 is a C1 to C8 straight or branched chain alkyl group, the two groups X and X', which may be the same or different, may be attached to the same carbon atom in the alkyl chain or to different carbon atoms in the alkyl chain, -L5- is a linking group which is    -(L1)n- or  -- R8 --     wherein R8 and (L1)n are as defined above in relation to formula (IIIA) and R11 is C1 to C4 alkyl;   and wherein in formula (IVA) Y and Y' are each, independently, a straight or branched chain C1 to C10 alkyl group, a polyoxyethylene, polyoxypropylene or polyoxybutylene polymer chain of formula -(L1)n- as defined above or a group -(L2) -- R9 --  as defined above. 2. A microcapsule according to claim 1 wherein when  -- Z is sulphonate, carboxylate, phosphonate or phosphate it is present as a salt providing the  -- Z- anion; or   when  -- Z is quaternary ammonium it has the structure    [ -- NR1R2R3]+A'-    wherein R1, R2 and R3 are independently hydrogen or C1 to C4 alkyl and A'- is a suitable inorganic or organic anion, provided that not more than one of R1, R2 and R3 is hydrogen; or   when  -- Z is oxyetheylene or an oxyethylene-containing polymer, it is an oxyethylene polymer or is a random or block oxyethylene/oxypropylene copolymer containing an oxyethylene to oxypropylene ratio of greater than 1. 3. A microcapsule according to claim 1 wherein the polymer resin is made by the polymerisation of a urea formaldehyde prepolymer and the mole ratio of the surface modifying agent to the number of urea-formaldehyde repeat units in the urea formaldehyde prepolymer is between 1:40 to 1:4. 4. A microcapsule according to claim 1 wherein the encapsulated liquid comprises an agrochemical, an ink, a dye, a biologically active material or a pharmaceutical. 5. A modified process for the encapsulation of a liquid within a solid permeable shell of a polymer resin formed by polymerisation of a wall-forming material which comprises making said polymer resin by the polymerisation of a urea formaldehyde prepolymer in which the methylol ( -- CH2OH) groups have optionally been partially etherified by reaction with a C4-C10 alkanol, incorporating therein at least one surface modifying compound having a moiety  -- X which reacts with the methylol or etherified methylol moieties in the urea formaldehyde prepolymer;   wherein said surface modifying compound is of formula (IA), (IB), (IC), (ID), (IIA), (IIB), (IIC), (IIIA), (IIIB), (IIIC), (IIID) or (IVA) or is a sulfonate polyester polyol    X -- Y1 -- Z  (IA)       R4 -- O(PO)r(EO)s -- X  (IB)       R4' -- O(PO)r'(EO)s'(PO)t -- X  (IC)       X-(EO)a(PO)b -- X'  (IIA)       X -- (PO)a'(EO)b'(PO)cX'  (IIB)       X -- Y2 -- C(Z)(R6) -- Y2' -- X'  (IIIA)       X -- Y -- NH -- Y' -- Z  (IVA)    wherein the sulfonate polyester polyol is prepared by reacting sodium sulphoisophthalic acid, adipic acid, cyclohexane dimethanol, methoxy-polyethylene glycol (MW 750) and trimethylol propane to give a product having a hydroxyl number in the range of from 150 to 170;   and wherein in formulae (IA), (IB), (IC), (IIA), (IIB), (IIC), (IIIA), (IIIB), (IIIC), (IIID) and (IVA) above Z if present is sulphonate, carboxylate, phosphonate, phosphate, quaternary ammonium, betaine, oxyethylene or an oxyethylene-containing polymer;   and wherein in formulae (ID) above Z is sulphonate, phosphonate, phosphate, quaternary ammonium, betaine, oxyethylene or an oxyethylene-containing polymer; and each X or X' is, independently, hydroxyl, thiol, a group  -- NHA wherein A is hydrogen or C1 to C4 alkyl, or a group  -- CO -- OR where R is hydrogen or a hydrocarbyl moiety having 1-30 carbon atoms optionally linked or substituted by one or more halo, amino, ether or thioether groups or combinations of these;    and wherein in formula (IA) Y1 is a moiety linking X and Z and is a straight or branched alkyl chain containing from 1 to 20 carbon atoms or is naphthyl, cyclopentyl or cyclohexyl;   and wherein in formula (IB) R4 is an end-capping group which is C1 to C4 alkyl, r and s are independently from 0 to 3000, provided that s is not 0 and the total of r+s is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively which may be arranged in random or block formation;   and wherein in formula (IC) R4' is an end-capping group which is C1 to C4 alkyl, r', s' and t are, independently, from 0 to 2000, provided that s' is not 0 and the total of r'+s'+t is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively;   and wherein formula (ID) X and Z are as defined above; or X and Z are adjacent substituents which together with the carbon atoms to which they are bound form a cyclic anhydride capable of ring-opening;   and wherein in formula (IIA) a and b are independently from 0 to 3000, provided that a is not 0 and the total of a+b is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively which may be arranged in random or block formation;   and wherein in formula (IIB) a', b' and c are, independently, from 0 to 2000, provided that b' is not 0 and the total of a'+b'+c is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively;   and wherein in formula (IIC) R14 and R15, which may be the same or different, are hydrogen, C1 to C20 straight or branched chain alkyl, aryl or C1 to C4 aralkyl, wherein each aryl group may be optionally substituted by C1 to C4 alkyl, nitro or halo, and Y4 and Y4' which may be the same or different are     -- R8 --  or  -- R7-(L1)n-    wherein R7 and R8 are, independently, C1 to C10 straight or branched chain alkyl linking groups optionally substituted by halogen or C1 to C4 alkoxy and (L1)n is a polyoxyalkyene group wherein n is from 2 to 20 and A- is a suitable anion;   and wherein in formula (IIIA) R6 is hydrogen or a C1 to C4 alkyl group optionally substituted by ether or halogen and Y2 and Y2', which may be same or different, are independently     -- R7-(L1)n- or  -- R8 --     wherein R7 and R8 are, independently, C1 to C10 straight or branched chain alkyl linking groups optionally substituted by halogen or C1 to C4 alkoxy and (L1)n is polyoxyethylene, polyoxypropylene or polyoxybutylene where n is from 2 to 20;   and wherein in formula (IIIB) X and Z are as previously defined;   and wherein in formula (IIIC) Y3, Y3' and Y3'' individually represent a direct link between X or Z (as the case may be) and the ring structure or may be a group    -(L2)-R9 --     where L2 is an ester linking group  -- C(O) -- O --  and R9 is oxyethylene, oxypropylene or oxybutylene or polyoxyethylene, polyoxypropylene or polyoxybutylene having a degree of polymerisation from 2 to 20;   and wherein in formula (IIID) R10 is a C1 to C8 straight or branched chain alkyl group, the two groups X and X', which may be the same or different, may be attached to the same carbon atom in the alkyl chain or to different carbon atoms in the alkyl chain, -L5- is a linking group which is    -(L1)n- or  -- R8 --     wherein R8 and (L1)n are as defined above in relation to formula (IIIA) and R11 is C1 to C4 alkyl;   and wherein in formula (IVA) Y and Y' are each, independently, a straight or branched chain C1 to C10 alkyl group, a polyoxyethylene, polyoxypropylene or polyoxybutylene polymer chain of formula -(L1)n- as defined above or a group -(L2)-R9 --  as defined above. 6. A process according to claim 5 comprising (a) reacting the surface-modifying compound with a urea formaldehyde prepolymer thereby forming a modified surface-active intermediate;   (b) preparing an organic solution or oil phase comprising the matcrial liquid to be encapsulated, the modified surface-active intermediate, and;   (c) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and, optionally, a protective colloid, wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution; and either   (d) causing in situ polymerization and/or curing of the modified prepolymer in the organic solution of the discrete droplets at the interface with the aqueous solution by heating the emulsion for a sufficient period of time and optionally adjusting the pH to a suitable value to allow substantial completion of wall formation, thereby converting the organic solution droplets to capsules consisting of solid, permeable, polymer shells enclosing the material and having the surface modifying compound incorporated therein; or as an alternative to (d)   (e) causing polymerization at the oil-water interface by bringing together a prepolymer added through the aqueous continuous phase and capable of reacting with the wall forming material(s) in the discontinuous oil phase. 7. A process according to claim 5 comprising (a) preparing an organic solution or oil phase comprising the material to be encapsulated, the surface modifying compound and the wall-forming material;   (b) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and, optionally, a protective colloid, wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution; and either   (c) causing in situ polymerization and/or curing of the modified wall-forming material in the organic solution of the discrete droplets at the interface with the aqueous solution by heating the emulsion for a sufficient period of time and optionally adjusting the pH to a suitable value to allow substantial completion of wall formation, thereby converting the organic solution droplets to capsules consisting of solid, permeable, modified polymer shells enclosing the material; or as an alternative to (c)   (d) causing polymerization at the oil-water interface by bringing together a wall forming material added through the aqueous continuous phase and capable of reacting with the wall forming material(s) in the discontinuous oil phase. 8. A process according to claim 5 comprising (a) preparing an organic solution or oil phase comprising the liquid to be encapsulated and the urea-formaldehyde prepolymer;   (b) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and the surface-modifying compound(s), wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution; and   (c) causing in situ polymerization and/or curing of the urea-formaldehyde prepolymer so that the surface-modifying molecule(s) is incorporated into the wall by heating the emulsion for a sufficient period of time and optionally adjusting the pH to a suitable value, to allow substantial completion of wall formation, thereby converting the organic solution droplets to capsules consisting of solid, permeable, modified polymer shells enclosing the liquid. 9. A process according to claim 5 comprising (a) preparing an organic solution or oil phase comprising the material to be encapsulated and a first wall-forming material(s);   (b) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and the surface-modifying compound(s), wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution whereupon the surface modifying compounds(s) react at the interface with wall forming material from the organic phase; and   (c) causing polymerization at the oil-water interface by bringing together a second wall forming material added through the aqueous continuous phase and capable of reacting with the first wall forming material(s) in the discontinuous oil phase. 10. A process according to claim 5 wherein there is employed a combination of the processes selected from at least two of the following: 1) a process comprising a) reacting the surface-modifying compound with at least one wall-forming material thereby forming a modified surface-active intermediate;   b) preparing an organic solution or oil phase comprising the material to be encapsulated, the modified surface-active intermediate, and, optionally, additional wall-forming material;   c) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and, optionally, a protective colloid, wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution; and either   d) causing in situ polymerization and/or curing of the modified wall-forming material in the organic solution of the discrete droplets at the interface with the aqueous solution by heating the emulsion for a sufficient period of time and optionally adjusting the pH to a suitable value to allow substantial completion of wall formation, thereby converting the organic solution droplets to capsules consisting of solid, permeable, polymer shells enclosing the material and having the surface modifying compound incorporated therein, or as an alternative to (d)   e) causing polymerization at the oil-water interface by bringing together a wall forming material added through the aqueous continuous phase and capable of reacting with the wall forming material(s) in the discontinuous oil phase;    2) a process comprising a) preparing an organic solution or oil phase comprising the material to be encapsulated, the surface modifying compound and the wall-forming material   b) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and, optionally, a protective colloid, wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution; and either   c) causing in situ polymerization and/or curing of the modified wall-forming material in the organic solution of the discrete droplets at the interface with the aqueous solution by heating the emulsion for a sufficient period of time and optionally adjusting the pH to a suitable value to allow substantial completion of wall formation, thereby converting the organic solution droplets to capsules consisting of solid, permeable, modified polymer shells enclosing the material; or as an alternative to (c)   d) causing polymerization at the oil-water interface by bringing together a wall forming material added through the aqueous continuous phase and capable of reacting with the wall forming material(s) in the discontinuous oil phase;    3) a process comprising a) preparing an organic solution or oil phase comprising the material to be encapsulated and the wall-forming material;   b) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and the surface-modifying compound(s), wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution; and   c) causing in situ polymerization and/or curing of the wall-forming material so that the surface-modifying molecule(s) is incorporated into the wall by heating the emulsion for a sufficient period of time and optionally adjusting the pH to a suitable value, to allow substantial completion of wall formation, thereby converting the organic solution droplets to capsules consisting of solid, permeable, modified polymer shells enclosing the material; and    4) a process comprising a) preparing an organic solution or oil phase comprising the material to be encapsulated and a first wall-forming material(s);   b) creating an emulsion of the organic solution in a continuous phase aqueous solution comprising water and the surface-modifying compound(s), wherein the emulsion comprises discrete droplets of the organic solution dispersed throughout the continuous phase aqueous solution, with an interface formed between the discrete droplets of organic solution and the aqueous solution whereupon the surface modifying compounds(s) react at the interface with wall forming material from the organic phase; and   c) causing polymerization at the oil-water interface by bringing together a second wall forming material added through the aqueous continuous phase and capable of reacting with the first wall forming material(s) in the discontinuous oil phase. 11. A process according to claim 5 wherein the encapsulated liquid comprises an agrochemical, an ink, a dye, a biologically active material or a pharmaceutical. 12. A method for modifying the soil mobility of an agrochemical, comprising: (a) encapsulating the agrochemical within a solid permeable shell of a polymer resin wherein: said polymer resin is made by the polymerisation of a urea formaldehyde prepolymer in which the methylol ( -- CH2OH) groups have optionally been partially etherified by reaction with a C4-C10 alkanol, incorporating therein at least one surface modifying compound having a moiety  -- X which reacts with the methylol or etherified methylol moieties in the urea formaldehyde prepolymer;   wherein said surface modifying compound is of formula (IA), (IB), (IC), (ID), (IIA), (IIB), (IIC), (IIIA), (IIIB), (IIIC), (IIID) or (IVA) or is a sulfonate polyester polyol    X -- Y1 -- Z  (IA)       R4 -- O(PO)r(EO)s -- X  (IB)       R4' -- O(PO)r'(EO)s'(PO)t -- X  (IC)       X-(EO)a(PO)b -- X'  (IIA)       X -- (PO)a'(EO)b'(PO)c -- X'  (IIB)       X -- Y2 -- C(Z)(R6) -- Y2' -- X'  (IIIA)       X -- Y -- NH -- Y' -- Z  (IVA)    wherein the sulfonate polyester polyol is prepared by reacting sodium sulphoisophthalic acid, adipic acid, cyclohexane dimethanol, methoxy-polyethylene glycol (MW 750) and trimethylol propane to give a product having a hydroxyl number in the range of from 150 to 170;   and wherein in formulae (IA), (IB), (IC), (IIA), (IIB), (IIC), (IIIA), (IIIB), (IIIC), (IIID) and (IVA) above Z if present is sulphonate, carboxylate, phosphonate, phosphate, quaternary ammonium, betaine, oxyethylene or an oxyethylene-containing polymer;   and wherein in formulae (ID) above Z is sulphonate, phosphonate, phosphate, quaternary ammonium, betaine, oxyethylene or an oxyethylene-containing polymer; and each X or X' is, independently, hydroxyl, thiol, a group  -- NHA wherein A is hydrogen or C1 to C4 alkyl, or a group  -- CO -- OR where R is hydrogen or a hydrocarbyl moiety having 1-30 carbon atoms optionally linked or substituted by one or more halo, amino, ether or thioether groups or combinations of these;    and wherein in formula (IA) Y1 is a moiety linking X and Z and is a straight or branched alkyl chain containing from 1 to 20 carbon atoms or is naphthyl, cyclopentyl or cyclohexyl;   and wherein in formula (IB) R4 is an end-capping group which is C1 to C4 alkyl, r and s are independently from 0 to 3000, provided that s is not 0 and the total of r+s is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively which may be arranged in random or block formation;   and wherein in formula (IC) R4' is an end-capping group which is C1 to C4 alkyl, r', s' and t are, independently, from 0 to 2000, provided that s' is not 0 and the total of r'+s'+t is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively;   and wherein formula (ID) X and Z are as defined above; or X and Z are adjacent substituents which together with the carbon atoms to which they are bound form a cyclic anhydride capable of ring-opening;   and wherein in formula (IIA) a and b are independently from 0 to 3000, provided that a is not 0 and the total of a+b is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively which may be arranged in random or block formation;   and wherein in formula (IIB) a', b' and c are, independently, from 0 to 2000, provided that b' is not 0 and the total of a'+b'+c is from 7 to 3000, and EO and PO represent oxyethylene and oxypropylene respectively;   and wherein in formula (IIC) R14 and R15, which may be the same or different, are hydrogen, C1 to C20 straight or branched chain alkyl, aryl or C1 to C4 aralkyl, wherein each aryl group may be optionally substituted by C1 to C4 alkyl, nitro or halo, and Y4 and Y4' which may be the same or different are     -- R8 --  or  -- R7-(L1)n-    wherein R7 and R8 are, independently, C1 to C10 straight or branched chain alkyl linking groups optionally substituted by halogen or C1 to C4 alkoxy and (L1)n is a polyoxyalkyene group wherein n is from 2 to 20 and A- is a suitable anion;   and wherein in formula (IIIA) R6 is hydrogen or a C1 to C4 alkyl group optionally substituted by ether or halogen and Y2 and Y2', which may be same or different, are independently     -- R7-(L1)n- or  -- R8 --     wherein R7 and R8 are, independently, C1 to C10 straight or branched chain alkyl linking groups optionally substituted by halogen or C1 to C4 alkoxy and (L1)n is polyoxyethylene, polyoxypropylene or polyoxybutylene where n is from 2 to 20;   and wherein in formula (IIIB) X and Z are as previously defined;   and wherein in formula (IIIC) Y3, Y3' and Y3'' individually represent a direct link between X or Z (as the case may be) and the ring structure or may be a group    -(L2)-R9 --     where L2 is an ester linking group  -- C(O) -- O --  and R9 is oxyethylene, oxypropylene or oxybutylene or polyoxyethylene, polyoxypropylene or polyoxybutylene having a degree of polymerisation from 2 to 20;   and wherein in formula (IIID) R10 is a C1 to C8 straight or branched chain alkyl group, the two groups X and X', which may be the same or different, may be attached to the same carbon atom in the alkyl chain or to different carbon atoms in the alkyl chain, -L5- is a linking group which is    -(L1)n- or  -- R8 --     wherein R8 and (L1)n are as defined above in relation to formula (IIIA) and R11 is C1 to C4 alkyl;   and wherein in formula (IVA) Y and Y' are each, independently, a straight or branched chain C1 to C10 alkyl group, a polyoxyethylene, polyoxypropylene or polyoxybutylene polymer chain of formula -(L1)n- as defined above or a group -(L2) -- R9 --  as defined above; and   (b) applying the encapsulated agrochemical to soil.
法律状态
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