(AU2018269387) Delayed release feed-through veterinary compositions with ovicidal and larvicidal activity against susceptible and resistant strains of parasites in ruminants' feces, use of these compositions, method for delaying the release of these compositions 机翻标题: 暂无翻译,请尝试点击翻译按钮。

源语言标题
(AU2018269387) Delayed release feed-through veterinary compositions with ovicidal and larvicidal activity against susceptible and resistant strains of parasites in ruminants' feces, use of these compositions, method for delaying the release of these compositions
公开号/公开日
AU2018269387 / 2019-11-07
申请号/申请日
AU2018269387 / 2018-04-26
发明人
DA ROCHA FLAVIA SETTEDA ROCHA FLAVIO ALVES;
申请人
CHAMPION;
主分类号
IPC分类号
A01N-043/40 A01N-043/60 A61K-009/14 A61K-009/16 A61K-009/48
摘要
(AU2018269387) A veterinary composition is disclosed and is based on anthelmintic compounds, particularly from the benzimidazole group, with delayed release properties, preferably in the form of granules or pellets, to be added to feed or feed supplements offered to ruminants in order to control eggs and larvae of helminths, preferably from the genus
机翻摘要
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地址
代理人
(AU2018269387) Watermark Intellectual Property Pty Ltd ([AU])
代理机构
;
优先权号
2017BR-0010598 2017US-15823965 2018WO-US29492
主权利要求
(AU2018269387) 1. A composition for the control of eggs and larvae of a helminth that develops in ruminant feces, comprising: (a) at least one benzimidazole compound; (b) at least one hydrophobic polymer; (c) at least one particulate solid carrier, and (d) optionally, at least one hydrophilic polymer. 2. The composition of claim 1, wherein said helminth is of the Haemonchus genre, and the ruminant feces is from the suborder of Ruminantia. 3. The composition of claim 1, wherein the benzimidazole compound is thiabendazole, fenbendazole, albendazole, triclabendazole, cambendazole, parbendazole, mebendazole, flubendazole, oxfendazole, carbendazim, fuberidazole, triazoxide, ricobendazole, oxilbendazole, or a derivative thereof, or any combination thereof. 4. The composition of claim 1, wherein the benzimidazole compound is thiabendazole, fenbendazole, or albendazole, or any combination thereof. 5. The composition of claim 1, wherein the hydrophobic polymer is ethylcellulose, zein, a methyl methacrylate copolymer, or any combination thereof. 6. The composition of claim 1, wherein the hydrophilic polymer is present. 7. The composition of claim 1, wherein the particulate solid carrier is microcrystalinne cellulose, calcium phosphate, calcium sulfate, mannitol, kaolin, or any combination thereof. 8. The composition of claim 1, further comprising a stabilizer, a flavoring agent, a flavor enhancer, a preservative, a tensoactive, a lubricant, a diluent, a lubricant, a pH adjustment agent, or an antioxidant, or any combination thereof. 9. A feed or feed supplement composition comprising a) feed or feed supplement offered to animals and b) an efficacious amount of said composition of claim 1. 10. The feed or feed supplement composition of claim 9, wherein the feed is ground or pelletized. 11. The feed or feed supplement composition of claim 9, wherein the feed supplement is sodium chloride, mineralized salt, calcium phosphate, a vitamin concentrate, a protein supplement, or any combination thereof. 12. A kit for controlling nematodes that develop in ruminant's feces comprising a canister containing the composition of claim 1 and a dosing device. 13. The kit of claim 12 further comprising written instructions for its use. 14. The kit of claim 12, wherein the canister contains about 300 g of said composition and a 25g-dosing device for dosing of said composition. 15. The kit of claim 12, wherein said canister is a pail containing about 6 kg of said composition and a 25g-dosing device for dosing of said composition. 16. A method to control eggs and larvae of helminths present in ruminants' feces, said method comprising administering to an animal, by oral route, through means of feed or feed supplement, the composition of claim 1. 17. The method of claim 16, wherein said method enhances zootechnical performance of ruminants by means of controlling eggs and infective larvae in their habitat. 18. The composition of claim 1, wherein said benzimidazole compound is present in an amount of from 0.1 wt% to about 20 wt%, based on the total weight of said composition. 19. The composition of claim 1, wherein said benzimidazole compound is present in an amount of from 0.1 wt% to about 20 wt%, said hydrophobic polymer is present in an amount of from about 5 wt% to about 55 wt%, said hydrophilic polymer is present in an amount of from 0 wt% to about 40 wt% and said particulate solid carrier is present in an amount of from 40 wt% to about 75 wt%, based on a total weight of said composition. 20. The composition of claim 1, wherein said benzimidazole compound in said composition is bioactively released on a delayed release basis. 21. The composition of claim 20, wherein said delayed release is from about 10 hours to 72 hours from consumption of the composition by an animal. 22. The method of claim 16, wherein said composition is delayed released with respect to said benzimidazole compound such that the release occurs in the feces of said ruminant. 23. The method of claim 16, wherein said animal after 10 hours to 72 hours has a residue of said benzimidazole compound of less than 100 ppm. 24. The method of claim 16, wherein said animal after 10 hours to 72 hours has a residue of said benzimidazole compound of less than 1 ppm. 25. The composition of claim 1, wherein said hydrophilic polymer is present and is hypromellose, polyvinylpyrrolidone, carragenine, hydroxipropilmethylcellulose, or any combination thereof 26. The composition of claim 1, wherein one or more of the following is additional present in the composition: starch, talcum powder, calcium carbonate, silicon dioxide, ethyl citrate, or any combination. 27. The composition of claim 1, wherein said benzimidazole compound is present in an amount of from 0.1 wt% to about 20 wt%, said hydrophobic polymer is present in an amount of from about 5 wt% to about 55 wt%, said hydrophilic polymer is present in an amount of from 2.5 wt% to about 30 wt% and said particulate solid carrier is present in an amount of from 40 wt% to about 75 wt%, based on a total weight of said composition.
法律状态
PENDING
专利类型码
A1
国别省市代码
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