Para-substituted indanyl and tetralinyl derivatives 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US20180215740 A1 2018-08-02 [US20180215740] / 2018-08-02
申请号/申请日
2016US-15746029 / 2016-07-13
发明人
DATTA GOPAL KRISHNA;BINDSCHAEDLER PASCAL;VON DEYN WOLFGANG;RACK MICHAEL;KOERBER KARSTEN;
申请人
BASF;
主分类号
IPC分类号
A01N-043/10A01N-043/20A01N-043/36A01N-043/40A01N-043/54A01N-043/78A01N-043/80C07D-207/20C07D-261/04C07D-333/24C07D-403/12C07D-409/12C07D-413/12C07D-417/12
摘要
(US20180215740) is also disclosed.  Additionally, the use of compounds of formula I or formula II for the production of active compounds is disclosed.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2015EP-0177883 2015-07-22 2016WO-EP66603 2016-07-13
主权利要求
(US20180215740) 1. Compounds of formula I   wherein the variables have the following meaning:   X Cl, Br, or I;   R1 H, OR11, or NR12R13; R11 a) H; b) C1-C6-alkyl, C3-C8-cycloalkyl, C2-C6-alkenyl, C3-C8-cycloalkenyl, C2-C6-alkynyl;   which groups are unsubstituted, or substituted by halogen, CN, NO2, phenyl, S(O)mRA, ORB, NRBRC, S(O)mNRBRC, Si(RB)2RC, C(.dbd.O)RB, C(.dbd.O)NRBRC, C(.dbd.O)ORB, C(.dbd.S)RB, C(.dbd.S)NRBRC, C(.dbd.S)ORB, C(.dbd.S)SRB, C(.dbd.NRB)RC, C(.dbd.NRB)NRCRD;   c) phenyl, which is unsubstituted, or substituted by RA; or   d) a 3-, 4-, 5-, 6-, or 7-membered saturated, partially unsaturated or fully unsaturated heterocycle, which heterocycle comprises one, or more, same, or different heteroatoms O, N(O)n, or S(O)m;   wherein   RA a) C1-C6-alkyl, C3-C8-cycloalkyl-C1-C4-alkyl, C1-C4-alkyl-C3-C8-cycloalkyl, C3-C8-cycloalkyl, C2-C6-alkenyl, C2-C6-alkynyl, phenyl; which groups are unsubstituted, or substituted by halogen, CN, OH, NO2, phenyl, or C1-C6-alkyl-phenyl;   b) a 3-, 4-, 5-, 6-, or 7-membered saturated, partially unsaturated or fully unsaturated heterocycle, which heterocycle comprises one, or more, same, or different heteroatoms O, N(O)n, and S(O)m, wherein none, one, or more ring members are replaced by C(.dbd.O), or C(.dbd.S), and which heterocycle is unsubstituted, or substituted by halogen, CN, N3, NO2, SCN, SF5, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-alkoxy-C1-C6-alkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, or C2-C6-haloalkynyl;    RB, RC, RD are independently from one another, as defined for RA, or H; or two substituents RB, RC, or RD, together with the atom, or the atoms to which they are bound, form a 3, 4, 5, 6, or 7-membered saturated, partially unsaturated, or fully unsaturated carbocycle, or heterocycle, which cycles are unsubstituted, or substituted by RA, and wherein the heterocycle comprises one, or more, same, or different heteroatoms O, N(O)n, or S(O)m, and wherein none, one, or more ring members are replaced by C(.dbd.O), or C(.dbd.S);    R12 H, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, phenyl; which groups are unsubstituted, or substituted by RE;   R13 a) H, C1-C6-alkyl, C1-C6-alkoxy, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C6-alkyl, phenyl; which groups are unsubstituted, or substituted by RE; b) a group Z-A, wherein Z is a chemical bond, CH2, CH2CH2 or C.dbd.O; and A is a 3-, 4-, 5-, 6- or 7-membered saturated, partially unsaturated or fully unsaturated heterocycle, which heterocycle is unsubstituted or substituted by RF and comprises one, or more, same, or different heteroatoms O, N(O)n, and S(O)m, and wherein none, one, or more ring members are replaced by C(.dbd.O), or C(.dbd.S), C(.dbd.NRB), or C(.dbd.NORB);   c) a group S(O)mRA, S(O)mN(RB)RC, N(RB)RC, N(RB)C(.dbd.O)ORC, N(RB)C(.dbd.O)N(RC)RD, N(RB)C(.dbd.S)ORC, N(RB)C(.dbd.S)N(RC)RD, C(.dbd.O)N(RB)RC, C(.dbd.S)N(RB)RC, C(.dbd.O)ORA, C.dbd.NORA, C.dbd.NRARB, C.dbd.NRBRC; or wherein R12 and R13, together with the N-atom to which they are bound, form a 3, 4, 5, 6, or 7-membered saturated, partially unsaturated, or fully unsaturated carbocycle, or heterocycle, which cycles are unsubstituted, or substituted by RF, and wherein the heterocycle comprises one, or more, same, or different heteroatoms O, N(O)n, and S(O)m, and wherein none, one, or more ring members are replaced by C(.dbd.O), or C(.dbd.S), C(.dbd.NRB), or C(.dbd.NORB);    or wherein R12 and R13, together with the N-atom to which they are bound, form a group .dbd.S(RB)RC, .dbd.NRB, .dbd.NORB, or .dbd.NN(RB)RC;   RE a) halogen, CN, N3, NO2, SCN, SF5, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6-haloalkynyl, Si(RB)2RC, OR11, OSO2RA, S(O)mRA, S(O)mN(RB)RC, N(RB)RC, C(.dbd.O)N(RB)RC, C(.dbd.O)N(RB)N(RC)RD, C(.dbd.O)NORB, C(.dbd.S)N(RB)RC, C(.dbd.O)ORA; b) phenyl, which is unsubstituted, or substituted by RA; or   c) two substituents RE, together with the atom, or the atoms to which they are bound, form a 3, 4, 5, 6, or 7-membered saturated, partially unsaturated, or fully unsaturated carbocycle, or heterocycle, which cycles are unsubstituted, or substituted by RA, and wherein the heterocycle comprises one, or more, same, or different heteroatoms O, N(O)n, or S(O)m, and wherein none, one, or more ring members are replaced by C(.dbd.O), or C(.dbd.S), C(.dbd.NRB), or C(.dbd.NORB);    RF a) halogen, CN, N3, NO2, SCN, SF5, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy-C1-C6-alkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6-haloalkynyl, Si(RB)2RC, OR11, OSO2RA, S(O)mRA, S(O)mN(RB)RC, N(RB)RC, C(.dbd.O)N(RB)RC, C(.dbd.O)N(RB)N(RC)RD, C(.dbd.O)NORB, C(.dbd.S)N(RB)RC, C(.dbd.O)ORA; b) phenyl, which is unsubstituted, or substituted by RA; or   c) two substituents RF, together with the atom, or the atoms to which they are bound, form a 3, 4, 5, 6, or 7-membered saturated, partially unsaturated, or fully unsaturated carbocycle, or heterocycle, which cycles are unsubstituted, or substituted by RA, and wherein the heterocycle comprises one, or more, same, or different heteroatoms O, N(O)n, and S(O)m, and wherein none, one, or more ring members are replaced by C(.dbd.O), or C(.dbd.S), C(.dbd.NRB), or C(.dbd.NORB);    k 1, or 2   m 0, 1, or 2;   n 0, or 1.00069 2. The compounds according to claim 1, wherein k is 1. 3. The compounds according to claim 1, wherein k is 2. 4. The compounds according to claim 1, wherein R1 is OR11, and R11 is H, C1-C6-alkyl, phenyl, or benzyl. 5. The compounds according to claim 4, wherein R11 is C1-C4-alkyl. 6. A process for the production of compounds I, as defined in claim 1, by reaction of compounds II with a reducing agent.   7. The process according to claim 6, wherein compounds II are produced by reaction of compounds V   with H2O, R11OH, or NHR12R13; wherein X is Cl, Br, or I, and U is halogen; and   wherein compounds V are produced by reaction of compounds III    with a halogenating agent, followed by cyclization in the presence of a Lewis acid. 8. The process according to claim 7, wherein compounds III are produced by reaction of compounds IV selected from IVa, IVb, or IVc   with hydrogen, followed by hydrolysis; wherein R2 is CN, or C(.dbd.O)ORA. 9. The process according to claim 8, wherein the hydrogen is produced in situ from a) a metal selected from alkali metals, and alkaline earth metals, or   b) a metal with a redox potential below 0 at a pH below 7.0. 10. (canceled) 11. Compounds of formula VI   produced from compounds of formula 1 as defined in claim 1, wherein R3 is H, or CH3, and k and R1 have a meaning as defined in claim 1.00074 12. Insecticidal compounds of formula XIV-A or XV-A   produced from compounds of formula 1 as defined in claim 1, wherein V is selected from CH, N, and NO, W is selected from O, S and CH2, and R7, R8, and R9 are independently hydrogen, halogen, halomethyl, or halomethoxy, wherein at most two substituents R7, R8, and R9 are H, and R1, R13, and k have a meaning as defined in claim 1.00075 13. (canceled) 14. (canceled) 15. (canceled) 16. The insecticidal compounds of claim 12, wherein the compounds of formula 1 are produced by reaction of compounds II with a reducing agent.
法律状态
(US20180215740) LEGAL DETAILS FOR US20180215740  Actual or expected expiration date=2036-07-13    Legal state=ALIVE    Status=PENDING     Event publication date=2016-07-13  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US15746029  Application date=2016-07-13  Standardized application number=2016US-15746029     Event publication date=2016-07-13  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: DANIEL, LAURA M    Event publication date=2016-07-13  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1624     Event publication date=2016-07-13  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: 27843-1221 0000078579US01    Event publication date=2016-07-13  Event code=US/CUST  Event type=Examination events  Attorney/Agent Customer Number Customer Nbr: 76656    Event publication date=2016-07-13  Event code=US/ENT  Event type=Administrative notifications  Entity Status Set to Undiscounted Business Entity Status: UNDISCOUNTED    Event publication date=2016-07-13  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=Yes     Event publication date=2018-01-19  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2018-01-19  Event code=US/PTARDY  Event indicator=Pos  Event type=Examination events  Patent Term Adjustment - Ready for Examination    Event publication date=2018-01-19  Event code=US/ENT  Event type=Administrative notifications  Entity Status Set to Undiscounted    Event publication date=2018-03-22  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2018-04-24  Event code=US/M903  Event indicator=Pos  Event type=Examination events  Event type=OAO  Notice of DO/EO Acceptance Mailed    Event publication date=2018-04-24  Event code=US/APPFILEREC  Event type=Administrative notifications  Event type=OAO  Filing Receipt    Event publication date=2018-06-27  Event code=US/DKNC  Event indicator=Pos  Event type=Examination events  Docketed New Case - Ready for Examination    Event publication date=2018-06-27  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=2018-08-02  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US20180215740  Publication stage Code=A1  Publication date=2018-08-02  Standardized publication number=US20180215740     Event publication date=2018-08-02  Event code=US/PGPUBN  Event indicator=Pos  Event type=Examination events  Event type=OAO  PG-Pub Issue Notification
专利类型码
A1
国别省市代码
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