COULD CO-ADMINISTRATION OF VITAMINS E AND C INCREASE TOTAL ANTIOXIDANT CAPACITY? A SYSTEMATIC REVIEW AND META-ANALYSIS 机翻标题: 暂无翻译,请尝试点击翻译按钮。

来源
Current topics in nutraceutical research
年/卷/期
2018 / 16 / 4
页码
253-262
ISSN号
1540-7535
作者单位
Lorestan Univ Med Sci, Nutr Hlth Res Ctr, Khorramabad, Iran;Lorestan Univ Med Sci, Nutr Hlth Res Ctr, Khorramabad, Iran;Lorestan Univ Med Sci, Nutr Hlth Res Ctr, Khorramabad, Iran;Lorestan Univ Med Sci, Student Res Comm, Khorramabad, Iran;Lorestan Univ Med Sci, Student Res Comm, Khorramabad, Iran;Qazvin Univ Med Sci, Student Res Comm, Qazvin, Iran;Lorestan Univ Med Sci, Student Res Comm, Khorramabad, Iran;Lorestan Univ Med Sci, Student Res Comm, Khorramabad, Iran;Qazvin Univ Med Sci, Student Res Comm, Qazvin, Iran;Lorestan Univ Med Sci, Nutr Hlth Res Ctr, Khorramabad, Iran;
作者
Saboori, Somayeh;Falahi, Ebrahim;Birjandi, Mehdi;Hesami, Sepideh;Veisi, Fatemeh;Hosseini, Mohammad Ali;Aghayan, Maryam;Mohiti, Sara;Rasouli, Ahmad;Rad, Esmaeil Yousefi;
摘要
The aim of this meta-analysis was to assess effects of supplementation with vitamin E, vitamin C or a combination of the two vitamins on total antioxidant capacity (TAC) in clinical trial studies. A systematic search was carried out for clinical trials. in PubMed Scopus and Cochrane Library databases published up to July 2017. Of 4176 relevant studies searched, only 17 studies with 9, 8 and 10 arms selected respectively for the meta-analysis assessing the effects of vitamin E, vitamin C and a combination of the two vitamins on TAC. Pooled effects analysis showed that co-administration of vitamins E and C could significantly increase TAC by 0.09 mmol/l (95% CI = 0.03, 0.16; P < 0.001). In sub-group analysis based on the supplementation dose and trial duration, no differences were seen in TAC between the groups. Meta regression analysis showed that the baseline TAC included a significant association with the effects of vitamin E (P = 0.001), vitamin C (P < 0.001) and a combination of the two vitamins (P = 0.004) on the final TAC. Results of the current meta-analysis showed that co-administration of vitamins E and C could significantly increase the TAC.
机翻摘要
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关键词/主题词
Meta-analysis;TAC;Total antioxidant capacity;Vitamin C;Vitamin E;
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