(EP2814820) The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation. In one embodiment, the invention provides aminopyrazine derivatives having the following formula: (From US9266842 B2)
(EP2814820) 1. An aminopyrazine according to Formula (I), (see diagram) wherein X is CR **1 or N; Y is selected from CF 3, -C(O)-NR **3R **4; O-R **6; SO 2-R **6; R **1 is selected from H and halogen; R **2 is selected from SO 2-R **5 and -C(O)-R **10; R **3 and R **4 are independently selected from H and optionally substituted C 1-C 6 alkyl; R **5 is selected from -NR **7R **8 and R **9; R **6 is optionally substituted C 1-C 6 alkyl; R **7 and R **8 are independently selected from H and optionally substituted C 1-C 6 alkyl; R **9 is optionally substituted C 1-C 6 alkyl or optionally substituted C 3-C 8 cycloalkyl; R **10 is -NR **11R **12; R **11 and R **12 are independently selected from H and optionally substituted C 1-C 6 alkyl or NR **11R **12 form together an optionally substituted heterocycloalkyl; as well as pharmaceutically acceptable salts, complexes, hydrates, solvates, or polymorphs, tautomers, geometrical isomers, optically active forms thereof, wherein optionally substituted refers to groups substituted with from 1 to 5 substituents selected from the group consisting of "C 1-C 6 alkyl," " "C 3-C 8-cycloalkyl," "amino," "halogen," hydroxy, and nitro.
(EP2814820) LEGAL DETAILS FOR EP2814820 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Event publication date=2013-02-15 Event code=EP/APP Event indicator=Pos Event type=Examination events Application details Application country=EP EP13712926 Application date=2013-02-15 Standardized application number=2013EP-0712926 Event publication date=2014-12-24 Event code=EP/A1 Event type=Examination events Application published with search report Publication country=EP Publication number=EP2814820 Publication stage Code=A1 Publication date=2014-12-24 Standardized publication number=EP2814820 Event publication date=2014-12-24 Event code=EP/17P Event indicator=Pos Event type=Examination events Request for examination filed Pruefungsantrag gestellt Effective date of the event=2014-09-09 Event publication date=2014-12-24 Event code=EP/AK Event indicator=Pos Event type=Designated states Designated contracting states: Benannte vertragsstaaten AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Event publication date=2014-12-24 Event code=EP/AX Event indicator=Pos Event type=Designated states Extension of the European patent to Request for extension of the european patent to BA ME Event publication date=2015-09-30 Event code=EP/17Q Event indicator=Pos Event type=Examination events First examination report Erster pruefungsbescheid Effective date of the event=2015-08-31 Event publication date=2016-04-20 Event code=EP/INTG Event indicator=Pos Event type=Examination events Announcement of intention to grant Effective date of the event=2016-03-29 Event publication date=2016-07-20 Event code=EP/B1 Event indicator=Pos Event type=Event indicating In Force Patent specification Publication country=EP Publication number=EP2814820 Publication stage Code=B1 Publication date=2016-07-20 Standardized publication number=EP2814820 Event publication date=2016-07-20 Event code=EP/AK Event indicator=Pos Event type=Designated states Designated contracting states: Benannte vertragsstaaten AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Event publication date=2016-07-20 Event code=EP/AX Event indicator=Pos Event type=Designated states Extension of the European patent to Request for extension of the european patent to BA ME Event publication date=2017-06-28 Event code=EP/26N Event indicator=Pos Event type=No opposition filed Event type=Event indicating In Force No opposition filed Kein einspruch eingelegt Effective date of the event=2017-04-21 MEMBER STATE LEGAL DETAILS FOR AL Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=AL Event publication date=2017-02-20 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-20 Year of payment of annual fees=5 Corresponding cc: Designated or member state=AL MEMBER STATE LEGAL DETAILS FOR AT Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=AT Corresponding appl: AT813974 Event publication date=2016-08-15 Event code=EP/REG Event code=AT/REF Event indicator=Pos Event type=Entry into national phase Reference to a national code Reference to at number (ep patent enters austrian national phase) Nennung der e-nummer (ep patent tritt in at nationale phase ein) Corresponding cc: Designated or member state=AT Effective date of the event=2016-08-15 MEMBER STATE LEGAL DETAILS FOR BE Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=BE Event publication date=2017-02-16 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-16 Year of payment of annual fees=5 Corresponding cc: Designated or member state=BE MEMBER STATE LEGAL DETAILS FOR BG Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=BG Event publication date=2017-02-23 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-23 Year of payment of annual fees=5 Corresponding cc: Designated or member state=BG MEMBER STATE LEGAL DETAILS FOR CH Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=CH Event publication date=2016-07-29 Event code=EP/REG Event code=CH/EP Event indicator=Pos Event type=Entry into national phase Reference to a national code Entry in the national phase Eintritt in die nationale phase Corresponding cc: Designated or member state=CH Event publication date=2016-08-31 Event code=EP/REG Event code=CH/NV Event type=Change of name or address Reference to a national code New agent Neuer vertreter/nouveaux mandataires/nuovi mandatari Corresponding cc: Designated or member state=CH Representative: REUTELER AND CIE S.A., CH Event publication date=2017-02-22 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-22 Year of payment of annual fees=5 Corresponding cc: Designated or member state=CH MEMBER STATE LEGAL DETAILS FOR CY1118074 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=CY Corresponding appl: CY161100998 Application date in the designated or member state=2016-10-10 Application number in the designated or member state=1998CY-1611009 Corresponding cc: Designated or member state=CY Corresponding pat: CY1118074 Publication stage code in the designated or member state=T1 Publication date in the designated or member state=2017-06-28 Publication number in the designated or member state=CY1118074 Event publication date=2017-06-28 Event code=CY/STCHG Patent status changed by the national office Corresponding cc: Designated or member state=CY MEMBER STATE LEGAL DETAILS FOR CZ Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=CZ Event publication date=2017-02-14 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-14 Year of payment of annual fees=5 Corresponding cc: Designated or member state=CZ MEMBER STATE LEGAL DETAILS FOR DE Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=DE Corresponding appl: DE602013009584 Event publication date=2016-09-01 Event code=EP/REG Event code=DE/R096 Event indicator=Pos Event type=Examination events Reference to a national code DPMA publication of mentioned EP patent grant Veroeffentlichung eines hinweises auf die ep-patenterteilung durch das dpma Corresponding cc: Designated or member state=DE Event publication date=2017-02-17 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-17 Year of payment of annual fees=5 Corresponding cc: Designated or member state=DE Event publication date=2017-04-21 Event code=EP/REG Event code=DE/R097 Event indicator=Pos Event type=No opposition filed Reference to a national code No opposition filed against granted patent, or EPO opposition proceedings concluded without decision Gegen die patenterteilung wurde kein einspruch erhoben, bzw. einspruchsverfahren ist beim epa ohne entscheidung abgeschlossen Corresponding cc: Designated or member state=DE MEMBER STATE LEGAL DETAILS FOR DK2814820 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=DK Corresponding appl: DK13712926 Application date in the designated or member state=2013-02-15 Application number in the designated or member state=2013DK-0712926 Corresponding cc: Designated or member state=DK Corresponding pat: DK2814820 Publication stage code in the designated or member state=T3 Publication date in the designated or member state=2016-10-03 Publication number in the designated or member state=DK2814820T Event publication date=2016-10-03 Event code=EP/REG Event code=DK/T3 Event indicator=Pos Event type=Event indicating In Force Reference to a national code Translation of EP patent Corresponding cc: Designated or member state=DK Effective date of the event=2016-09-29 Event publication date=2017-02-16 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-16 Year of payment of annual fees=5 Corresponding cc: Designated or member state=DK MEMBER STATE LEGAL DETAILS FOR EE Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=EE Corresponding appl: EEE012678 Event publication date=2016-12-15 Event code=EP/REG Event code=EE/FG4A Event indicator=Pos Event type=Examination events Reference to a national code Translation of the specification of european patent valid in estonia Estis kehtivate euroopa patentide patendikirjelduse tolked Corresponding cc: Designated or member state=EE Effective date of the event=2016-10-17 Event publication date=2017-02-20 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-20 Year of payment of annual fees=5 Corresponding cc: Designated or member state=EE MEMBER STATE LEGAL DETAILS FOR ES2589283 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=ES Corresponding appl: ES13712926 Application date in the designated or member state=2013-02-15 Application number in the designated or member state=2013ES-0712926T Corresponding cc: Designated or member state=ES Corresponding pat: ES2589283 Publication stage code in the designated or member state=T3 Publication date in the designated or member state=2016-11-11 Publication number in the designated or member state=ES2589283 Event publication date=2016-11-11 Event code=EP/REG Event code=ES/FG2A Event indicator=Pos Event type=Event indicating In Force Reference to a national code Definitive protection Proteccion definitiva Corresponding cc: Designated or member state=ES Effective date of the event=2016-11-11 Event publication date=2017-02-13 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-13 Year of payment of annual fees=5 Corresponding cc: Designated or member state=ES MEMBER STATE LEGAL DETAILS FOR FI Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=FI Event publication date=2017-02-13 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-13 Year of payment of annual fees=5 Corresponding cc: Designated or member state=FI MEMBER STATE LEGAL DETAILS FOR FR Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=FR Event publication date=2017-02-17 Event code=EP/REG Event code=FR/PLFP Event indicator=Pos Event type=Payment or non-payment notifications Event type=Restitution or restoration Reference to a national code Fee payment Derniere annuite payee Annual fees payment date=2017-02-17 Year of payment of annual fees=5 Corresponding cc: Designated or member state=FR Event publication date=2017-02-17 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-17 Year of payment of annual fees=5 Corresponding cc: Designated or member state=FR MEMBER STATE LEGAL DETAILS FOR GB Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=GB Event publication date=2016-07-20 Event code=EP/REG Event code=GB/FG4D Event indicator=Pos Event type=Event indicating In Force Reference to a national code European patent granted Corresponding cc: Designated or member state=GB Event publication date=2017-02-16 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-16 Year of payment of annual fees=5 Corresponding cc: Designated or member state=GB MEMBER STATE LEGAL DETAILS FOR GR Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=GR Corresponding appl: GR20160402396 Event publication date=2017-02-17 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-17 Year of payment of annual fees=5 Corresponding cc: Designated or member state=GR Event publication date=2017-03-02 Event code=EP/REG Event code=GR/EP Event indicator=Pos Event type=Event indicating In Force Reference to a national code Ep patent validated in greece Corresponding cc: Designated or member state=GR Effective date of the event=2017-01-17 MEMBER STATE LEGAL DETAILS FOR HK1202859 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=HK Corresponding appl: HK15103337 Application date in the designated or member state=2015-04-01 Application number in the designated or member state=2015HK-0103337 Corresponding cc: Designated or member state=HK Corresponding pat: HK1202859 Publication stage code in the designated or member state=A1 Publication date in the designated or member state=2015-10-09 Publication number in the designated or member state=HK1202859 Event publication date=2015-10-09 Event code=EP/REG Event code=HK/DE Event type=Examination events Reference to a national code Requests to designate patent in hong kong Requests to record published in hong kong Corresponding cc: Designated or member state=HK Event publication date=2015-10-09 Event code=HK/STCHG Patent status changed by the national office Corresponding cc: Designated or member state=HK MEMBER STATE LEGAL DETAILS FOR HRP20161237 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=HR Corresponding appl: HRP20161237 Application date in the designated or member state=2016-09-28 Application number in the designated or member state=2016HR-0001237 Corresponding cc: Designated or member state=HR Corresponding pat: HRP20161237 Publication stage code in the designated or member state=T1 Publication date in the designated or member state=2016-11-04 Publication number in the designated or member state=HRP20161237 Event publication date=2017-02-09 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-09 Year of payment of annual fees=5 Corresponding cc: Designated or member state=HR MEMBER STATE LEGAL DETAILS FOR HUE029876 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=HU Corresponding appl: HUE13712926 Application date in the designated or member state=2013-02-15 Application number in the designated or member state=2013HU-E712926 Corresponding cc: Designated or member state=HU Corresponding pat: HUE029876 Publication stage code in the designated or member state=T2 Publication date in the designated or member state=2017-04-28 Publication number in the designated or member state=HUE029876 Event publication date=2017-02-17 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-17 Year of payment of annual fees=5 Corresponding cc: Designated or member state=HU Event publication date=2017-04-28 Event code=EP/REG Event code=HU/AG4A Event indicator=Pos Event type=Examination events Reference to a national code Filing of the translation of the text of european patents Eurpai szabadalmak szoevege forditasanak benyujtasa Corresponding cc: Designated or member state=HU MEMBER STATE LEGAL DETAILS FOR IE Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=IE Event publication date=2016-08-10 Event code=EP/REG Event code=IE/FG4D Event indicator=Pos Event type=Event indicating In Force Reference to a national code European patents granted designating ireland Corresponding cc: Designated or member state=IE Event publication date=2017-02-20 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-20 Year of payment of annual fees=5 Corresponding cc: Designated or member state=IE MEMBER STATE LEGAL DETAILS FOR IS Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=IS Event publication date=2017-02-13 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-13 Year of payment of annual fees=5 Corresponding cc: Designated or member state=IS MEMBER STATE LEGAL DETAILS FOR IT Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=IT Event publication date=2017-02-21 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-21 Year of payment of annual fees=5 Corresponding cc: Designated or member state=IT MEMBER STATE LEGAL DETAILS FOR LT Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=LT Event publication date=2017-02-10 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-10 Year of payment of annual fees=5 Corresponding cc: Designated or member state=LT MEMBER STATE LEGAL DETAILS FOR LU Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=LU Event publication date=2017-02-16 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-16 Year of payment of annual fees=5 Corresponding cc: Designated or member state=LU MEMBER STATE LEGAL DETAILS FOR LV Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=LV Event publication date=2017-02-13 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-13 Year of payment of annual fees=5 Corresponding cc: Designated or member state=LV MEMBER STATE LEGAL DETAILS FOR MC Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=MC Event publication date=2017-02-14 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-14 Year of payment of annual fees=5 Corresponding cc: Designated or member state=MC MEMBER STATE LEGAL DETAILS FOR NL Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=NL Event publication date=2016-10-28 Event code=EP/REG Event code=NL/FP Event type=Event indicating Not In Force Event type=Payment or non-payment notifications Reference to a national code Translation for ep filed (entry of ep into country) Description in original language not provided Corresponding cc: Designated or member state=NL Event publication date=2017-02-16 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-16 Year of payment of annual fees=5 Corresponding cc: Designated or member state=NL MEMBER STATE LEGAL DETAILS FOR NO Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=NO Event publication date=2016-11-14 Event code=EP/REG Event code=NO/T2 Event indicator=Pos Event type=Entry into national phase Reference to a national code Entry of ep patent into national phase of norway Europeisk patent (b1) med virking i norge Corresponding cc: Designated or member state=NO Effective date of the event=2016-07-20 Event publication date=2017-02-20 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-20 Year of payment of annual fees=5 Corresponding cc: Designated or member state=NO MEMBER STATE LEGAL DETAILS FOR PL2814820 Actual or expected expiration date=2023-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=PL Corresponding appl: PL13712926 Application date in the designated or member state=2013-02-15 Application number in the designated or member state=2013PL-0712926 Corresponding cc: Designated or member state=PL Corresponding pat: PL2814820 Publication stage code in the designated or member state=T3 Publication date in the designated or member state=2017-01-31 Publication number in the designated or member state=PL2814820 Event publication date=2017-02-10 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-10 Year of payment of annual fees=5 Corresponding cc: Designated or member state=PL MEMBER STATE LEGAL DETAILS FOR PT Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=PT Event publication date=2017-02-15 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-15 Year of payment of annual fees=5 Corresponding cc: Designated or member state=PT MEMBER STATE LEGAL DETAILS FOR RO Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=RO Event publication date=2016-10-17 Event code=EP/REG Event code=RO/EPE Event indicator=Pos Event type=Event indicating In Force Reference to a national code Ep patent valid in romania Corresponding cc: Designated or member state=RO Event publication date=2017-02-10 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-10 Year of payment of annual fees=5 Corresponding cc: Designated or member state=RO MEMBER STATE LEGAL DETAILS FOR RS Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=RS Event publication date=2017-02-10 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-10 Year of payment of annual fees=5 Corresponding cc: Designated or member state=RS MEMBER STATE LEGAL DETAILS FOR SE Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=SE Event publication date=2016-11-08 Event code=EP/REG Event code=SE/TRGR Event indicator=Pos Event type=Event indicating In Force Event type=Entry into national phase Reference to a national code Translation of granted ep patent Europeiska patent som uppraetthalls i aendrad avfattning Corresponding cc: Designated or member state=SE Event publication date=2017-02-16 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-16 Year of payment of annual fees=5 Corresponding cc: Designated or member state=SE MEMBER STATE LEGAL DETAILS FOR SIEP2814820 Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=SI Corresponding appl: SI201330290 Application date in the designated or member state=2013-02-15 Application number in the designated or member state=2013SI-0030290 Corresponding cc: Designated or member state=SI Corresponding pat: SIEP2814820 Publication stage code in the designated or member state=T1 Publication date in the designated or member state=2016-10-28 Publication number in the designated or member state=SIEP2814820T Event publication date=2017-02-09 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-09 Year of payment of annual fees=5 Corresponding cc: Designated or member state=SI MEMBER STATE LEGAL DETAILS FOR SK Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=SK Corresponding appl: SKE 22236 Event publication date=2017-02-02 Event code=EP/REG Event code=SK/T3 Event indicator=Pos Event type=Event indicating In Force Reference to a national code Translation of european patent specification into slovakian Spristupnene preklady europskych spisov Corresponding cc: Designated or member state=SK Event publication date=2017-02-14 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-14 Year of payment of annual fees=5 Corresponding cc: Designated or member state=SK MEMBER STATE LEGAL DETAILS FOR SM Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=SM Event publication date=2016-12-12 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2016-12-12 Year of payment of annual fees=5 Corresponding cc: Designated or member state=SM MEMBER STATE LEGAL DETAILS FOR TR Actual or expected expiration date=2033-02-15 Legal state=ALIVE Status=GRANTED Corresponding cc: Designated or member state=TR Event publication date=2017-02-13 Event code=EP/PGFP Event indicator=Pos Event type=Event indicating In Force Event type=Payment or non-payment notifications Postgrant: annual fees paid to national office Annual fees payment date=2017-02-13 Year o(...)
最新评论
暂无评论。