Mussel digestive gland as a model tissue for assessing xenobiotics: An overview 机翻标题: 暂无翻译,请尝试点击翻译按钮。

来源
Science of the Total Environment
年/卷/期
2018 / 636 /
页码
220-229
ISSN号
0048-9697
作者单位
Univ Messina, Dept Chem Biol Pharmaceut & Environm Sci, Viale Ferdinando Stagno dAlcontres 31, I-98166 Sant Agata Di Messina, Italy;Univ Patras, Dept Biol, Fac Sci, Sect Anim Biol, Patras 26500, Greece;Univ Patras, Dept Biol, Fac Sci, Sect Anim Biol, Patras 26500, Greece;
作者
Faggio, Caterina;Tsarpali, Vasiliki;Dailianis, Stefanos;
摘要
Control strategies and routine biomonitoring programs arc commonly performed worldwide using sentinel marine invertebrates, such as mussels of the genus Mytilus, for assessing the "health status" of the aquatic environment. Those species can accumulate and tolerate xenobiotics at levels higher than those being present into the aquatic environment, thus providing accurate and reliable biological endpoints (e.g. physiological, behavioral, cellular, biochemical and molecular indices) that can be measured in their tissues. Taking under consideration the significance of bivalves for assessing the environmental hazard of xenobiotics being present into the water medium, as well as the key role of digestive gland as a target-tissue for the compounds ingested in the organism, the present study aimed to summarize available data on the effects of different categories of xenobiotic compounds, previously characterized as a potential threat for the marine ecosystems. In this context, different types of pharmaceuticals and personal care products (PPCPs), biocides, microplastics (MPs) and nanoparticles (NPs), currently investigated in mussels' digestive gland, using a battery of experimental approaches and analytical methods, as well as stress indices evaluation, are briefly described and further discussed in order to elucidate not only the presence and the toxic mode of action of xenobiotics, but also the important role of the digestive gland as a reliable target-tissue for investigating the effects of xenobiotics at cellular, biochemical, and molecular levels. (C) 2018 Elsevier B.V. All rights reserved.
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关键词/主题词
Biocides;Digestive gland;Mussels;Nanoparticles;Pharmaceuticals;Microplastics;
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