源语言标题

(JP2016196513) 補​体​関連​障害​を​処置​する​ため​の​方法​および​組成​物

公开号/公开日

JP2016196513 A 2016-11-24 [JP2016196513] / 2016-11-24

申请号/申请日

2016JP-0166460 / 2016-08-29

发明人

RUSSELL P ROTHER;CAMILLE BEDROSIAN;STEPHEN P SQUINTO;REONARD BELL;

申请人

ALEXION PHARMACEUTICALS;

主分类号

IPC分类号

A61K-035/22A61K-035/28A61K-035/30A61K-035/34A61K-035/36A61K-035/407A61K-035/42A61K-035/44A61K-039/395A61K-045/00A61L-027/00A61P-007/04A61P-009/00A61P-009/12A61P-013/12A61P-037/02

摘要

(JP2016196513) PROBLEM TO BE SOLVED: To provide methods and compositions for treating complement-associated disorders.SOLUTION: The disclosure relates to, inter alia, compositions comprising an inhibitor of human complement, and to the use of the compositions in methods for treating or preventing complement-associated disorders.  In some embodiments, the inhibitor is chronically administered to patients.  In some embodiments, the inhibitor is administered to a patient in the amount and with a frequency to maintain systemic complement inhibition and prevent breakthrough.  In some embodiments, the compositions comprise an antibody or antigen-binding fragment thereof that binds to a human complement component C5 protein or fragments of the protein such as C5a or C5b.SELECTED DRAWING: None

机翻摘要

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地址

代理人

代理机构

;

优先权号

2008US-61198803 2008-11-10 2008US-61199562 2008-11-18 2008US-61199563 2008-11-18 2008US-61199569 2008-11-18 2008US-61199764 2008-11-19 2008US-61200634 2008-12-01 2008US-61200635 2008-12-01 2008US-61200640 2008-12-01 2009US-61181788 2009-05-28 2009US-61228

主权利要求

法律状态

(JP2016196513) LEGAL DETAILS FOR JP2016196513  Actual or expected expiration date=2029-11-10    Legal state=ALIVE    Status=PENDING     Event publication date=2016-08-29  Event code=JP/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=JP JP2016166460  Application date=2016-08-29  Standardized application number=2016JP-0166460     Event publication date=2016-08-31  Event code=JP/A621  Event indicator=Pos  Event type=Examination events  Written request for application examination  Effective date of the event=2016-08-29  JAPANESE INTERMEDIATE CODE: A621     Event publication date=2016-11-24  Event code=JP/A  Event indicator=Pos  Event type=Examination events  Published application  Publication country=JP  Publication number=JP2016196513  Publication stage Code=A  Publication date=2016-11-24  Standardized publication number=JP2016196513     Event publication date=2017-05-22  Event code=JP/A131  Event indicator=Neg  Event type=Examination events  Notification of reasons for refusal  Effective date of the event=2017-05-22  JAPANESE INTERMEDIATE CODE: A131     Event publication date=2017-07-14  Event code=JP/A601  Event type=Examination events  Written request for extension of term  Effective date of the event=2017-07-14  JAPANESE INTERMEDIATE CODE: A601

专利类型码

A

国别省市代码

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