(US7807647) We claim: 1. A method for reducing tumor burden in a subject, wherein said method comprises: parenterally administering: an antigene oligonucleotide comprising SEQ ID NO:1438 to said subject wherein said subject exhibits symptoms of cancer, wherein said cancer is selected from prostate cancer, breast cancer, lymphoma, and leukemia. 2. The method of claim 1, wherein said administering results in a reduction in symptoms of cancer in said subject. 3. The method of claim 1, wherein said cancer is a prostate cancer. 4. The method of claim 1, wherein said subject is a non-human mammal. 5. The method of claim 1, wherein said subject is a human. 6. The method of claim 1, wherein said oligonucleotide is introduced to said subject at a dosage of between 1 mg to 100 mg per kg of body weight. 7. The method of claim 1, further comprising the step of administering a known chemotherapeutic agent to said subject. 8. The method of claim 7, wherein said known chemotherapeutic agent is docetaxel. 9. The method of claim 1, further comprising providing a drug delivery system for introducing said oligonucleotide to said subject. 10. The method of claim 9, wherein said drug delivery system comprises a liposome, said liposome selected from the group consisting of a neutral lipid and a lipid like compound. 11. The method of claim 9, wherein said drug delivery system comprises a liposome, said liposome comprising a cationic lipid. 12. The method of claim 1, wherein said cancer is selected from breast cancer, lymphoma, and leukemia. 13. The method of claim 1, wherein said cancer is selected from lymphoma.
(US7807647) LEGAL DETAILS FOR US2007213285 Actual or expected expiration date=2026-08-23 Legal state=ALIVE Status=GRANTED Event publication date=2005-09-22 Event code=US/APP Event indicator=Pos Event type=Examination events Application details Application country=US US11233312 Application date=2005-09-22 Standardized application number=2005US-11233312 Event publication date=2005-09-22 Event code=US/EXMR Event type=Administrative notifications USPTO Examiner Name Primary Examiner: EPPS -SMITH, JANET L Event publication date=2005-09-22 Event code=US/ART Event type=Administrative notifications USPTO Art Group ART=1633 Event publication date=2005-09-22 Event code=US/SMALL Event type=Administrative notifications Appl Has Filed a Verified Statement of Micro to Small Entity Status Business Entity Status: SMALL Event publication date=2005-09-22 Event code=US/AIA Event type=Administrative notifications First Inventor File Indicated: AIA=No Event publication date=2005-09-22 Event code=US/DK Event type=Examination events Attorney Docket Number Docket Nbr: 31899-28537/US Event publication date=2005-09-22 Event code=US/CUST Event type=Examination events Attorney/Agent Customer Number Customer Nbr: 758 Event publication date=2005-10-28 Event code=US/INCD Event type=Examination events Event type=OAO Notice Mailed--Application Incomplete--Filing Date Assigned Event publication date=2006-02-02 Event code=US/AS Event type=Change of name or address Event type=Reassignment Assignment Owner: PRONAI THERAPEUTICS, INC., MICHIGAN ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:SHEIKHNEJAD, GHOLAMREZA GOODWIN, NEAL OLSON, DAVID SIGNING DATES FROM 20060117 TO 20060124 REEL/FRAME:017526/0554 Event publication date=2006-02-02 Event code=US/AS Event type=Change of name or address Event type=Reassignment Assignment Owner: PRONAI THERAPEUTICS, INC., MICHIGAN ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:SHEIKHNEJAD, GHOLAMREZA GOODWIN, NEAL OLSON, DAVID REEL/FRAME:017526/0554 SIGNING DATES FROM 20060117 TO 20060124 Event publication date=2006-02-02 Event code=US/APE Event type=Corrections Preliminary amendments Event publication date=2006-06-20 Event code=US/IDS Event type=Examination events Event type=OAI Information Disclosure Statement Filed Event publication date=2006-12-08 Event code=US/APE Event type=Corrections Preliminary amendments Event publication date=2007-07-23 Event code=US/DOCK Event indicator=Pos Event type=Examination events Case Docketed to Examiner Event publication date=2007-08-17 Event code=US/CTNF Event type=Examination events Event type=OA Event type=OAO Non-Final Rejection Event publication date=2007-09-13 Event code=US/A1 Event type=Examination events Application published Publication country=US Publication number=US2007213285 Publication stage Code=A1 Publication date=2007-09-13 Standardized publication number=US20070213285 Event publication date=2007-09-13 Event code=US/PGPUBN Event indicator=Pos Event type=Examination events Event type=OAO PG-Pub Issue Notification Event publication date=2008-03-06 Event code=US/AINEA Event type=OAI Event type=Examination events Informal or Non-Responsive Amendment after Examiner Action Event publication date=2008-03-06 Event code=US/CTNFR Event type=Examination events Event type=OAI Response after Non-Final Action Event publication date=2008-03-06 Event code=US/136G Event type=OAO Request for Extension of Time - 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