Antimicrobial Dental Materials 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
US2011275675 A1 2011-11-10 [US20110275675] / 2011-11-10
申请号/申请日
2011US-13097100 / 2011-04-29
发明人
RIST KAI;SALZ ULRICH;RHEINBERGER VOLKER;
申请人
IVOCLAR VIVADENT;
主分类号
IPC分类号
A01N-043/40A01P-001/00C07D-401/06
摘要
(US20110275675) Dental material which contains an antimicrobial active ingredient according to general formula (I), in which R1=H, C1 to C3 alkylene residue; R2=a linear or branched C4 to C20 alkylene residue; R3=a C6 to C20 alkylene residue; and A−=Cl−, Br−, I−, F−, OH−, alkyl and aryl alcoholate, thiolate, NO3−, BO33−, PO43−, HPO42−, H2PO4−, alkyl and aryl phosphate, alkyl and aryl phosphonate, PF6−, TiF62−, BF4−, acetylacetonate, β-diketonate or anion of a β-keto ester.  The dental material is suitable in particular as tooth filling material, material for inlays or onlays, tooth cement, enamel/dentine adhesive, veneering material for crowns and bridges, or as material for false teeth.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2010EP-0162250 2010-05-07
主权利要求
(US20110275675) 1. Dental material comprising an antimicrobial active ingredient according to general formula (I),       in which R1=H, C1 to C3 alkylene residue;   R2=a linear or branched C4 to C20 alkylene residue;   R3=a C6 to C20 alkylene residue; and   A-=Cl-, Br-, I-, F-, OH-, alkyl and aryl alcoholate, thiolate, NO3-, BO33-, PO43-, HPO42-, H2PO4-, alkyl and aryl phosphate, alkyl and aryl phosphonate, PF6-, TiF62-, BF4-, acetylacetonate, beta -diketonate or anion of a beta -keto ester.00004 2. Dental material according to claim 1, which comprises an active ingredient according to formula (I), in which R1=H;   R2=a linear C8 alkyl residue;   R3=a linear C10 alkylene residue; and   A-=Cl-, alkyl phosphate, alkyl phosphonate. 3. Dental material according to claim 1, which comprises about 0.01-about 3.0 wt.-% of the active ingredient according to formula (I). 4. Dental material according to claim 1, which comprises about 0.05-about 1.5 wt.-% of the active ingredient according to formula (I). 5. Dental material according to claim 1, which comprises about 0.1-about 0.6 wt.-% of the active ingredient according to formula (I) 6. Dental material according to claim 1, which additionally comprises at least one polymerizable, ethylenically unsaturated monomer as binder and an initiator for the radical polymerization. 7. Dental material according to claim 1, which additionally comprises an organic and/or inorganic filler or a filler mixture. 8. Dental material according to claim 1, which comprises at least one monofunctional or polyfunctional (meth)acrylate or (meth)acryl amide or a mixture thereof as binder. 9. Dental material according to claim 1, which comprises a mixture of acidic and non-acidic monomers as binder. 10. Dental material according to claim 1, which additionally comprises a solvent. 11. Dental material according to claim 10, wherein the solvent comprises water, methanol, ethanol, phenoxyethanol, isopropanol, ethyl acetate, acetone or a mixture of two or more of the named solvents. 12. Dental material according to claim 1, which comprises about 0.01-about 3.0 wt.-%, active ingredient according to formula (I);   about 20 to about 95 wt.-% binder;   about 0.1 to about 5 wt.-% initiator; and optionally   0 to about 90 wt.-% filler; and optionally   0 to about 80 wt.-% solvent. 13. Dental material according to claim 1, which comprises about 0.05-about 1.5 wt.-% active ingredient according to formula (I);   about 30 to about 90 wt.-% binder,   about 0.3 to about 4.0 wt.-% initiator; and optionally   about 2 to about 85 wt.-% filler; and optionally   0 to about 60 wt.-% solvent. 14. Dental material according to claim 1, which comprises about 0.1-about 0.6 wt.-% active ingredient according to formula (I);   about 35 to about 80 wt.-% binder,   about 0.5 to about 3.5 wt.-% initiator; and optionally   about 10 to about 80 wt.-% filler; and optionally   0 to about 40 wt.-% solvent. 15. Process of using the dental material according to claim 1 as tooth filling material, material for inlays or onlays, tooth cement, veneering material for crowns and bridges, or as material for false teeth, materials for temporary restorations or as other materials for prosthetic, restorative and preventative dentistry. 16. Process of using the dental material according to claim 1 as enamel/dentine adhesive. 17. Process of using the dental material according to claim 1 as coating material for tooth fillings, restoration materials, dentures and natural teeth. 18. Process of using the dental material according to claim 1 to prevent tooth damage caused by Streptococcus mutans and/or lactobacilli. 19. Process of using the dental material according to claim 1 to prevent prosthesis incompatibilities caused by Candida albicans. 20. Process of using an active ingredient according to formula (I) to prepare a polymerizable dental material wherein formula (I) comprises       in which R1=H, C1 to C3 alkylene residue;   R2=a linear or branched C4 to C20 alkylene residue;   R3=a C6 to C20 alkylene residue; and   A-=Cl-, Br-, I-, F-, OH-, alkyl and aryl alcoholate, thiolate, NO3-, BO33-, PO43-, HPO42-, H2PO4-, alkyl and aryl phosphate, alkyl and aryl phosphonate, PF6-, TiF62-, BF4-, acetylacetonate, beta -diketonate or anion of a beta -keto ester.00005
法律状态
(US20110275675) LEGAL DETAILS FOR US2011275675  Actual or expected expiration date=2015-06-24    Legal state=DEAD    Status=LAPSED     Event publication date=2011-04-29  Event code=US/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=US US13097100  Application date=2011-04-29  Standardized application number=2011US-13097100     Event publication date=2011-04-29  Event code=US/EXMR  Event type=Administrative notifications  USPTO Examiner Name Primary Examiner: ROBERTS, LEZAH    Event publication date=2011-04-29  Event code=US/ART  Event type=Administrative notifications  USPTO Art Group  ART=1612     Event publication date=2011-04-29  Event code=US/ENT  Event type=Administrative notifications  Entity Status Set to Undiscounted Business Entity Status: UNDISCOUNTED    Event publication date=2011-04-29  Event code=US/AIA  Event type=Administrative notifications  First Inventor File Indicated:  AIA=No     Event publication date=2011-04-29  Event code=US/DK  Event type=Examination events  Attorney Docket Number Docket Nbr: 173P365    Event publication date=2011-04-29  Event code=US/CUST  Event type=Examination events  Attorney/Agent Customer Number Customer Nbr: 96448    Event publication date=2011-04-29  Event code=US/AS  Event type=Change of name or address  Event type=Reassignment  Assignment ASSIGNMENT OF ASSIGNORS INTEREST ASSIGNORS:RIST, KAI SALZ, ULRICH RHEINBERGER, VOLKER SIGNING DATESFROM 20110328 TO 20110331 REEL/FRAME:026198/0962     Event publication date=2011-04-29  Event code=US/IDS  Event type=Examination events  Event type=OAI  Information Disclosure Statement Filed    Event publication date=2011-05-17  Event code=US/APPFILEREC  Event type=Administrative notifications  Event type=OAO  Filing Receipt    Event publication date=2011-11-10  Event code=US/A1  Event type=Examination events  Application published  Publication country=US  Publication number=US2011275675  Publication stage Code=A1  Publication date=2011-11-10  Standardized publication number=US20110275675     Event publication date=2011-11-10  Event code=US/PGPUBN  Event indicator=Pos  Event type=Examination events  Event type=OAO  PG-Pub Issue Notification    Event publication date=2012-08-23  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=2012-09-24  Event code=US/RESTREQ  Event type=Examination events  Event type=Corrections  Event type=OAO  Restriction/Election Requirement    Event publication date=2012-10-10  Event code=US/ELC  Event type=Examination events  Event type=OAI  Response to Election / Restriction Filed    Event publication date=2013-01-26  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2013-05-30  Event code=US/CTNFR  Event type=Examination events  Event type=OAI  Response after Non-Final Action    Event publication date=2013-05-30  Event code=US/136G  Event type=OAO  Request for Extension of Time - Granted    Event publication date=2013-06-16  Event code=US/CTFR  Event type=Examination events  Event type=OA  Event type=OAO  Final Rejection    Event publication date=2013-07-29  Event code=US/INVSUM  Event type=Examination events  Event type=OAI  Event type=INT  Interview Summary- Applicant Initiated    Event publication date=2013-07-29  Event code=US/INVSUM  Event type=Examination events  Event type=OAI  Event type=INT  Interview Summary- Applicant Initiated    Event publication date=2013-09-20  Event code=US/RCEX  Event type=Examination events  Event type=RCE  Event type=OAI  Request for Continued Examination (RCE)    Event publication date=2013-10-04  Event code=US/DRCECAP  Event type=RCE  Event type=OAO  Disposal for a RCE / CPA / R129    Event publication date=2013-10-08  Event code=US/DOCK  Event indicator=Pos  Event type=Examination events  Case Docketed to Examiner    Event publication date=2014-12-15  Event code=US/CTNF  Event type=Examination events  Event type=OA  Event type=OAO  Non-Final Rejection    Event publication date=2015-06-24  Event code=US/ABNOA  Event indicator=Neg  Event type=Event indicating Not In Force  Event type=OAO  Abandoned -- Failure to Respond to an Office Action
专利类型码
A1
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