Meglumine for reducing or preventing the increase of triglyceride levels 机翻标题: 暂无翻译,请尝试点击翻译按钮。

公开号/公开日
EP3158995 A1 2017-04-26 [EP3158995] / 2017-04-26
申请号/申请日
2016EP-0195153 / 2013-08-08
发明人
TOBIA ANNETTE;
申请人
DYNAMIS THERAPEUTICS;
主分类号
IPC分类号
A61K-031/133A61K-045/06A61P-003/06
摘要
(EP3158995) The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.  The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
机翻摘要
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地址
代理人
代理机构
;
优先权号
2012US-61681241 2012-08-09 2013EP-0828183 2013-08-08 2013US-61770553 2013-02-28
主权利要求
(EP3158995) 1. Composition comprising an effective amount of meglumine or a salt thereof for reducing or preventing the increase of triglyceride levels, or reversing a physiological condition associated with high triglyceride levels in a subject in need thereof. 2. Composition according to claim 1, wherein the composition further comprises an acceptable carrier. 3. Composition according to claim 2, wherein the acceptable carrier is at least one selected from the group consisting of a liquid or solid filler, sugar, starch, cellulose or derivative thereof, powdered tragacanth, malt, gelatin, talc, oil, glycol, polyol, ester, agar, buffering agent, alginic acid, pyrogen-free water, isotonic saline, isotonic agent, Ringer's solution, ethyl alcohol, phosphate buffer solution, diluent, granulating agent, lubricant, binder, disintegrating agent, wetting agent, emulsifier, coloring agent, release agent, coating agent, sweetening agent, flavoring agent, perfuming agent, preservative, antioxidant, plasticizer, gelling agent, thickener, hardener, setting agent, suspending agent, surfactant, humectant, stabilizer, coating, antibacterial agent, antifungal agent, absorption delaying agent and lecithin. 4. Composition according to any of the preceding claims, wherein the composition is formulated for inhalational, oral, rectal, vaginal, parenteral, topical, transdermal, pulmonary, intranasal, buccal, ophthalmic, intrathecal, parenteral, intravenous, or another route of administration. 5. Composition according to any of the preceding claims, wherein the composition is formulated for injection. 6. Composition according to any of the preceding claims, wherein the composition is formulated for administration at a frequency selected from the group consisting of once a day, twice a day, three times a day, four times a day, once a week, twice a week, three times a week, four times a week, once a month, twice a month, and any combinations thereof. 7. Composition according to any of the preceding claims, wherein the composition is formulated for administration at a dosage ranging from about 1 ng/kg/application to about 100 g/kg/application. 8. Composition according to any of the preceding claims, wherein the composition is formulated for administration at a dosage ranging from about 1 ng/kg/application to about 100 mg/kg/application. 9. Composition according to any of the preceding claims, wherein the composition is a controlled-release formulation. 10. Composition according to any of the preceding claims, wherein the composition is combined with a medication for treating symptoms of diabetes. 11. Composition according to any of the preceding claims, wherein the subject is a mammal. 12. Composition according to any of the preceding claims, wherein the subject is a human.
法律状态
(EP3158995) LEGAL DETAILS FOR EP3158995  Actual or expected expiration date=2033-08-08    Legal state=ALIVE    Status=PENDING     Event publication date=2013-08-08  Event code=EP/APP  Event indicator=Pos  Event type=Examination events  Application details  Application country=EP EP16195153  Application date=2013-08-08  Standardized application number=2016EP-0195153     Event publication date=2017-04-26  Event code=EP/A1  Event type=Examination events  Application published with search report  Publication country=EP  Publication number=EP3158995  Publication stage Code=A1  Publication date=2017-04-26  Standardized publication number=EP3158995
专利类型码
A1
国别省市代码
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