(US9624458) A fibrous structure including filaments wherein the filaments comprise one or more filament-forming materials and one or more active agents that are releasable from the filament when exposed to conditions of intended use, the fibrous structure further having at least three regions. Methods of treating fabrics with a fibrous structure are also provided herein.
(US20150343113) The invention provides a polymeric medical sealant for use in mammals other than humans. The medical sealant is useful for application to the tonsils, adenoids or paranasal sinus, wherein the sealant performs at least one of the following functions, a) inhibit the colonization of bacteria, b) inhibit the binding of bacteria to tissue, c) reduction of tissue morbidity, d) hemostasis, e) coating and protection of tissue during healing, f) promotion of healing, and g) reduction of pain.
(US9371393) The present invention provides compositions and methods of use of humanized, chimeric or human Class I anti-CEA antibodies or fragments thereof, preferably comprising the light chain variable region CDR sequences SASSRVSYIH (SEQ ID NO:1); GTSTLAS (SEQ ID NO:2); and QQWSYNPPT (SEQ ID NO:3); and the heavy chain variable region CDR sequences DYYMS (SEQ ID NO:4); FIANKANGHTTDYSPSVKG (SEQ ID NO:5); and DMGIRWNFDV (SEQ ID NO:6). The Class I anti-CEA antibodies or fragments are useful for treating diseases, such as cancer, wherein the diseased cells express CEACAM5 and/or CEACAM6 antigens. The Class I anti-CEA antibodies or fragments are also of use for interfering with specific processes, such as metastasis, invasiveness and/or adhesion of cancer cells, or for enhancing sensitivity of cancer cells to cytotoxic agents and have favorable effects on the survival of subjects with cancer.
(JP3200648U) PROBLEM TO BE SOLVED: Not require a power source as a driving source, the manual operation and simple and generating bubbles can be a foam generator to provide the beverage. SOLUTION: Casing 8 in the large-diameter inlet 3, the diameter of the venturi passages 9, a negative pressure 10 and the enlarged portion 11 sequentially coaxially toward the downstream side is formed in communication with, the negative pressure chamber 10 diameter of the air flow path 12 radially outwardly from and in fluid communication with, the enlarged portion 11 and a larger diameter gradually toward a downstream is formed into a conical shape, a bottom surface facing the narrow flow paths a wide area of a collision wall 13 and, the enlarged portion 11 the bottom of the outer outlets 14 micro bubble generating device to form 2 is provided, the large-diameter inlet 3 a manually-operated pump for pumping the drink outlet 7 communicate with each other. SELECTED DRAWING: Fig. 2
(CR20170096) The present invention relates to combination therapies for treating a solid tumour in a subject. The combination therapies comprise (a) an antibody, or antigen-binding portion thereof, that specifically binds to CD40, and (b) a further immunotherapeutic agent with efficacy in the treatment of cancer, which agent is not an anti-CD40 antibody or antigen-binding fragment thereof. The invention also relates to a kits and methods of using such therapies. (From US2017226217 A1)