(NO20161561) A method of sealing a formation that includes drilling a wellbore through the formation while pumping a non-aqueous based wellbore fluid comprising a first sealing component into the wellbore, wherein the non-aqueous based wellbore fluid filters into the formation as a filtrate and substantially thickens is disclosed. The substantially thickening may result from adding a second sealing component to the wellbore fluid, whereby the first sealing component initiates a reaction of the second sealing component.
(NO20161559) A method of sealing a formation that includes drilling a wellbore through the formation while pumping a non-aqueous based wellbore fluid comprising an encapsulated first component into the wellbore, the non-aqueous based wellbore fluid forming a filter cake on the walls of the wellbore; and adding a second component to the wellbore fluid when fluid losses are registered during drilling, whereby the first and second components react to form a chemical sealing layer in the filter cake is disclosed.
(JP2017066404) PROBLEM TO BE SOLVED: To provide a polyolefin resin foamed sheet having improved thermal insulation performance while maintaining flexibility.SOLUTION: Provided is a polyolefin resin foamed sheet having a plurality of bubbles inside, wherein the 50% compressive strength is 120 kPa or less, the MD elongation rate is 400% or less, and the TD elongation rate is 200% or less.SELECTED DRAWING: None
(JP2017066401) PROBLEM TO BE SOLVED: To provide a wettability improver having excellent hydrophilicity imparting effect even when added in a small amount.SOLUTION: There is provided a wettability improver containing an ion binding salt represented by the following chemical formula (1), where R is a linear alkyl group having 12 to 14 carbon atoms which may be substituted, A is a linear or branched alkylene group having 2 to 4 carbon atoms, m is average addition molar number of AO and an integer of 2 to 50, (AO)contains at least 2 oxyalkylene groups and an alignment thereof may be a random type or a block type, n is a valence of Qand 1 or 2 and Qis a monovalent metal ion, a bivalent metal ion or a nitrogen-containing compound ion.SELECTED DRAWING: None
(JP2017066397) PROBLEM TO BE SOLVED: To provide a lipid derivative having a hydrophilic polymer bound thereto through an acetal linker, which can precisely regulate the hydrolysis rate in a weakly acidic environment in a living matter to eliminate the hydrophilic polymer from a lipid membrane structure.SOLUTION: Provided is a lipid derivative having a hydrophilic polymer bound thereto through a cyclic benzylidene acetal linker represented by a specific formula.SELECTED DRAWING: Figure 2
(WO201762252) An adhesive formulation including: (a) at least one polyol having an average functionality number of greater than 3 and a hydroxyl equivalent weight of from about 300 g/mol OH to about 3,000 g/mol OH; and (b) at least one tin catalyst compound; wherein the adhesive formulation exhibits a latency of greater than 10 minutes open time; and a process for preparing the adhesive formulation.
(WO201755395) The present invention generally relates to bispecific antigen binding molecules for activating T cells, more particularly bispecific antigen binding molecules for activating T cells targeting the Robo 4 receptor. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease. In addition, the invention also relates to antibodies that specifically bind to Robo 4.
FINNIS CHRISTOPHER JOHN ARTHUR;HAY JOANNA MARY;FRIIS ESBEN PETER;CAMERON JASON;SLEEP DARRELL
(US20170081389) Based on the three-dimensional structure of albumin, the inventors have designed variant polypeptides (muteins) which have one or more cysteine residues with a free thiol group (hereinafter referred to as “thio-albumin”). The variant polypeptide may be conjugated through the sulphur atom of the cysteine residue to a conjugation partner such as a bioactive compound.