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Totally found 1362600 items.

  • [专利] (WO2019185910) NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES
    (WO2019/185910) The present invention is directed towards the use of 2H-chromens and their derivatives of formula (I) and/or of formula (II) wherein R1 and R2 are independently from each other H or CM1-11 -alkyl or (CH2)n— OH with n being an integer from 1 to 6 or R1 and R2 together represent a keto group, and wherein R3, R4, R5, and R6 are independently from each other H or C1-6-alkyl or C1-6-alkoxy, and R7 is H or C1-6-alkyl, as antioxidants in PUFA-containing edible oils such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil for human consumption. The present invention is further directed towards these PUFA- containing edible oils comprising at least one compound of formula (I) and/or at least one compound of formula (II). The present invention is further directed to a method of preserving the shelf life of PUFAs and/or their esters in an edible oil comprising the step of adding at least one compound of formula (I) and/or at least one compound of formula (II) to said edible oil, as well as to a method of limiting the amount of oxidation of PUFAs and/or their esters in an edible oil which is exposed to air, comprising adding at least one compound of formula (I) and/or at least one compound of formula (II) to said edible oil, preferably in an amount of said compound of formula (I) and/or said compound of formula (II) ranging from 10 to 500 ppm, preferably ranging from 30 to 300 ppm, more preferably ranging from 100 to 250 ppm, based on the total amount of said edible oil.
  • [专利] (WO2019219153) Estimation of free water level and water-oil contact
    (WO2019/219153) This invention proposes a method for estimating the level of a Free Water Level (FWL) and Water-Oil Contact (OWC) based on finding two intersecting trends of the pressure gradient (1) for oil (non-wetting phase) and (2) water (wetting phase) in the oil interval based on the results of drilling only one exploration well, penetrating only the oil- saturated part of the reservoir and not penetrating the water-saturated part of the reservoir and OWC. The pressure gradient trend (1) for oil (the non-wetting phase) is determined based on the results of the formation tester (MWD) and (2) for water (the wetting phase) in the oil interval from the capillary pressure curve, set for the tank height based on petrophysical data and special laboratory tests of core taken from the oil- saturated zone. The point of intercepting the pressure gradient trends (1) for oil (non- wetting phase) and (2) for water (wetting phase) indicates the FWL in the tank and the WOC position.
  • [专利] (WO2019191370) Biologically enhanced oil recovery methods
    (WO2019/191370) Methods of enhancing oil recovery may include accessing a consortium of microorganisms in a geologic formation that includes oil. The methods may include delivering an aqueous material incorporating dissolved hydrogen to the consortium of microorganisms. The methods may include increasing production of gaseous materials by the consortium of microorganisms. The methods may also include recovering oil from the reservoir.
  • [专利] (WO2018102447) Food ingredients from stevia rebaudiana
    (WO2018/102447) The invention relates to a process for producing food ingredients from Stevia rebaudiana plant and their use in food products, beverages and other consumables. Obtained compositions are useful as flavors, sweeteners, antioxidants, and other functional ingredients.
  • [专利] (WO2019222222) Methods for microbial identification in clinical specimens by differential ribosomal rna probe hybridization
    (WO2019/222222) A method of identifying a target microbe in a specimen and including the steps of a) obtaining a specimen, b) lysing the specimen to release a plurality of rRNA molecules from one or more first target microbes in the specimen; c) contacting the specimen with a plurality of first oligonucleotide probe sets configured to selectively bind to rRNA molecules released from the target microbe thereby forming a plurality of first hybridized complexes, each first hybridized complex including one first capture probe and one first detector probe and one of the plurality of rRNA molecules, and d) analyzing the first hybridized complexes to identify a first target microbe in the specimen.
  • [专利] (WO201914310) Biological methods for preparing terpenes
    (WO2019/014310) The technology relates in part to biological methods for producing terpenes and to engineered cells and microorganisms capable of such production.
  • [专利] (WO202089942) A liquid injectable composition
    (WO2020/089942) A liquid injectable composition comprising (a) at least one surfactant; (b) at least one gel strength enhancer; (c) at least one solvent; (d) optionally release retarding agent(s); (e) optionally stabilizing agent(s); (f) optionally pharmaceutical excipient(s); and (g) active pharmaceutical ingredient(s) (API).& its use in treating a subject suffering from a disease or disorder.
  • [专利] (WO202036655) Methods of using genetic markers associated with endometriosis
    (WO2020/036655) Disclosed herein are methods of using genetic markers associated with endometriosis, for example via a computer-implemented program to predict risk of developing endometriosis, and methods of preventing or treating endometriosis or a symptom thereof. For example, the present disclosure provides a method of testing for endometriosis and treating a subject having at least one genetic mutation in at least one gene of UGT2B28, USP17L2 (alias DUB3), and METTL11B such that the subject is prevented from developing endometriosis or such that endometriosis in the subject is prevented from progressing. The treatment may be a surgical intervention, a hormone treatment, a pharmaceutical treating, or a combination thereof.
  • [专利] (WO202086885) Multivalent glycopeptides that tightly bind to carbohydrate-binding monoclonal antibody family pgt128
    (WO2020/086885) The invention relates to a glycopeptide that includes one or more modified amino acid residues having a sidechain comprising a monosaccharide or an oligosaccharide, wherein the glycopeptide binds specifically to a carbohydrate-binding monoclonal antibody from PGT128 family, preferably with an affinity of less than 100 nM. Immunogenic conjugates that include the glycopeptide, and pharmaceutical compositions that include the glycopeptide or the immunogenic conjugate are also disclosed. Various method of using the glycopeptides, immunogenic conjugates, and pharmaceutical compositions are disclosed, including inducing an immune response, inhibiting viral infection, treating a cancerous condition, and detecting a neutralizing antibody.
  • [专利] (WO202063370) 免疫组合物及其制备方法与应用
    (WO2020/063370) 本发明提供了一种免疫组合物及其制备方法与应用。 本发明通过原核表达体系或重组腺病毒体系高效表达VZV包膜gE糖蛋白及其gE鞭毛素融合蛋白。 将制得的重组gE蛋白、gE鞭毛素融合蛋白及重组腺病毒载体或其组合物免疫小鼠后可刺激机体产生高水平的gE和VZV特异性抗体滴度及gE和VZV特异性的细胞免疫,具有较好的免疫原性,可开发为新一代的改良型VZV疫苗。 不同于目前上市的减毒活疫苗,利用本发明开发的疫苗不会导致接种者有罹患带状疱疹的风险,并且本发明开发的疫苗比现有的含佐剂gE亚单位带状疱疹疫苗的副作用更低。
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